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The Critical Care Safety Study: The incidence and nature of adverse events and serious medical errors in intensive care

Rothschild, J.M., Landrigan, C.P., Cronin, J.W., Kaushal, R., Lockley, S.W., Burdick, E., Stone, P.H., Lilly, C.M., Katz, J.T., Czeisler, C.A. and Bates, D.W. (2005) The Critical Care Safety Study: The incidence and nature of adverse events and serious medical errors in intensive care Critical Care Medicine, 33 (8). pp. 1694-1700.

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Objective: Critically ill patients require high-intensity care and may be at especially high risk of iatrogenic injury because they are severely ill. We sought to study the incidence and nature of adverse events and serious errors in the critical care setting. Design: We conducted a prospective 1-year observational study. Incidents were collected with use of a multifaceted approach including direct continuous observation. Two physicians independently assessed incident type, severity, and preventability as well as systems-related and individual performance failures. Setting: Academic, tertiary-care urban hospital. Patients Medical intensive care unit and coronary care unit patients. Interventions: None. Measurements and Main Results: The primary outcomes of interest were the incidence and rates of adverse events and serious errors per 1000 patient-days. A total of 391 patients with 420 unit admissions were studied during 1490 patient-days. We found 120 adverse events in 79 patients (20.2%), including 66 (55%) nonpreventable and 54 (45%) preventable adverse events as well as 223 serious errors. The rates per 1000 patient-days for all adverse events, preventable adverse events, and serious errors were 80.5, 36.2, and 149.7, respectively. Among adverse events, 13% (16/120) were life-threatening or fatal; and among serious errors, 11% (24/223) were potentially life-threatening. Most serious medical errors occurred during the ordering or execution of treatments, especially medications (61%; 170/277). Performance level failures were most commonly slips and lapses (53%; 148/ 277), rather than rule-based or knowledge-based mistakes. Conclusions: Adverse events and serious errors involving critically ill patients were common and often potentially life-threatening. Although many types of errors were identified, failure to carry out intended treatment correctly was the leading category. Copyright © 2005 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins.

Item Type: Article
Authors :
Rothschild, J.M.
Landrigan, C.P.
Cronin, J.W.
Kaushal, R.
Burdick, E.
Stone, P.H.
Lilly, C.M.
Katz, J.T.
Czeisler, C.A.
Bates, D.W.
Date : 2005
DOI : 10.1097/01.CCM.0000171609.91035.BD
Uncontrolled Keywords : Adverse events, Critical care, Human factors, Intensive care unit, Medical errors, Patient safety, antibiotic agent, fentanyl, furosemide, heparin, imipenem, lorazepam, midazolam, tacrolimus, acute kidney failure, adult, aged, article, breathing disorder, cellulitis, critical illness, deep vein thrombosis, dehydration, disease severity, fatality, female, hospital admission, human, iatrogenic disease, ileus, incidence, intensive care, major clinical study, male, medical error, outcomes research, priority journal, prospective study, rash, side effect, tonic clonic seizure
Depositing User : Clive Harris
Date Deposited : 17 Jun 2020 01:59
Last Modified : 17 Jun 2020 01:59

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