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Lux vs. wavelength in light treatment of seasonal affective disorder

Anderson, J.L., Glod, C.A., Dai, J., Cao, Y. and Lockley, S.W. (2009) Lux vs. wavelength in light treatment of seasonal affective disorder Acta Psychiatrica Scandinavica, 120 (3). pp. 203-212.

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Objective: Published dosing guidelines for treatment of Seasonal Affective Disorder (SAD) refer to photopic lux, which is not appropriate for short-wavelength light. Short wavelengths are most potent for many non-visual responses to light. If SAD therapy were similarly mediated, standards utilizing lux risk overestimating necessary dose. We investigated antidepressant responses to light using two light-emitting diode (LED) sources, each emitting substantial short-wavelength light, but <2500 lux. Method: A randomized, double-blind trial investigated 3-week 45 min\day out-patient treatment with blue-appearing (goLITE®) or blue-enriched white-appearing light in 18 moderately-depressed adults (12F, 49.1 ± 9.5 years). Equivalent numbers of photons within the short-wavelength range were emitted, but the white source emitted twice as many photons overall and seven-fold more lux. Results: Depression ratings (SIGH-ADS; decrease averaged 82% (SD = 17%) from baseline (P < 0.0001) in both white- and blue-light groups. Both sources were well tolerated. Conclusion: Short-wavelength LED light sources may be effective in SAD treatment at fewer lux than traditional fluorescent sources. © 2009 Blackwell Munksgaard.

Item Type: Article
Authors :
Anderson, J.L.
Glod, C.A.
Dai, J.
Cao, Y.
Date : 2009
DOI : 10.1111/j.1600-0447.2009.01345.x
Uncontrolled Keywords : Melanopsin, Phototherapy, Seasonal affective disorder, adult, article, blue light, clinical article, clinical trial, controlled clinical trial, controlled study, double blind procedure, female, human, hyperactivity, light emitting diode, male, photon, phototherapy, priority journal, randomized controlled trial, remission, safety, seasonal affective disorder, treatment outcome, treatment response, white light, Adolescent, Adult, Circadian Rhythm, Diagnostic and Statistical Manual of Mental Disorders, Double-Blind Method, Female, Humans, Male, Middle Aged, Photons, Phototherapy, Seasonal Affective Disorder, Young Adult
Depositing User : Clive Harris
Date Deposited : 17 Jun 2020 01:49
Last Modified : 17 Jun 2020 01:49

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