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Measuring and using light in the melanopsin age

Lucas, R.J., Peirson, S.N., Berson, D.M., Brown, T.M., Cooper, H.M., Czeisler, C.A., Figueiro, M.G., Gamlin, P.D., Lockley, S.W., O'Hagan, J.B. , Price, L.L.A., Provencio, I., Skene, D.J. and Brainard, G.C. (2014) Measuring and using light in the melanopsin age Trends in Neurosciences, 37 (1). pp. 1-9.

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Light is a potent stimulus for regulating circadian, hormonal, and behavioral systems. In addition, light therapy is effective for certain affective disorders, sleep problems, and circadian rhythm disruption. These biological and behavioral effects of light are influenced by a distinct photoreceptor in the eye, melanopsin-containing intrinsically photosensitive retinal ganglion cells (ipRGCs), in addition to conventional rods and cones. We summarize the neurophysiology of this newly described sensory pathway and consider implications for the measurement, production, and application of light. A new light-measurement strategy taking account of the complex photoreceptive inputs to these non-visual responses is proposed for use by researchers, and simple suggestions for artificial/architectural lighting are provided for regulatory authorities, lighting manufacturers, designers, and engineers. © 2013 Elsevier Ltd.

Item Type: Article
Authors :
Lucas, R.J.
Peirson, S.N.
Berson, D.M.
Brown, T.M.
Cooper, H.M.
Czeisler, C.A.
Figueiro, M.G.
Gamlin, P.D.
O'Hagan, J.B.
Price, L.L.A.
Provencio, I.
Skene, D.J.
Brainard, G.C.
Date : 2014
DOI : 10.1016/j.tins.2013.10.004
Uncontrolled Keywords : cone opsin, melanopsin, scotopsin, melanopsin, evoked visual response, human, illumination, light, nonhuman, photoreceptor, phototransduction, priority journal, pupil reflex, retina ganglion cell, review, spectral sensitivity, stimulus response, vision, animal, circadian rhythm, metabolism, photoreceptor cell, phototherapy, physiology, trends, Animals, Circadian Rhythm, Humans, Photoreceptor Cells, Phototherapy, Retinal Ganglion Cells, Rod Opsins
Depositing User : Clive Harris
Date Deposited : 17 Jun 2020 01:23
Last Modified : 17 Jun 2020 01:23

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