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The UPBEAT depression and coronary heart disease programme: Using the UK medical research council framework to design a nurse-led complex intervention for use in primary care

Barley, Elizabeth A., Haddad, Mark, Simmonds, Rosemary, Fortune, Zoe, Walters, Paul, Murray, Joanna, Rose, Diana and Tylee, Andre (2012) The UPBEAT depression and coronary heart disease programme: Using the UK medical research council framework to design a nurse-led complex intervention for use in primary care BMC FAMILY PRACTICE, 13, 119.

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Background: Depression is common in coronary heart disease (CHD) and increases the incidence of coronary symptoms and death in CHD patients. Interventions feasible for use in primary care are needed to improve both mood and cardiac outcomes. The UPBEAT-UK programme of research has been funded by the NHS National Institute for Health Research (NIHR) to explore the relationship between CHD and depression and to develop a new intervention for use in primary care. Methods. Using the Medical Research Council (MRC) guidelines for developing and evaluating complex interventions, we conducted a systematic review and qualitative research to develop a primary care-based nurse-led intervention to improve mood and cardiac outcomes in patients with CHD and depression. Iterative literature review was used to synthesise our empirical work and to identify evidence and theory to inform the intervention. Results: We developed a primary care-based nurse-led personalised care intervention which utilises elements of case management to promote self management. Following biopsychosocial assessment, a personalised care plan is devised. Nurses trained in behaviour change techniques facilitate patients to address the problems important to them. Identification and utilisation of existing resources is promoted. Nurse time is conserved through telephone follow up. Conclusions: Application of the MRC framework for complex interventions has allowed us to develop an evidence based intervention informed by patient and clinician preferences and established theory. The feasibility and acceptability of this intervention is now being tested further in an exploratory trial. © 2012 Barley et al.; licensee BioMed Central Ltd.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Health Sciences
Authors :
Barley, Elizabeth
Haddad, Mark
Simmonds, Rosemary
Fortune, Zoe
Walters, Paul
Murray, Joanna
Rose, Diana
Tylee, Andre
Date : 12 December 2012
DOI : 10.1186/1471-2296-13-119
Copyright Disclaimer : © 2012 Barley et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Uncontrolled Keywords : Complex intervention, Coronary heart disease, Depression, Personalised care, Primary care, aged, article, case management, cohort analysis, coronary artery disease, depression, female, general practice, health care delivery, health personnel attitude, human, male, methodology, middle aged, nursing practice, patient care, patient care planning, patient education, primary health care, program development, psychological aspect, self care, United Kingdom, very elderly, Aged, Aged, 80 and over, Attitude of Health Personnel, Case Management, Cohort Studies, Coronary Disease, Delivery of Health Care, Depression, Female, General Practice, Great Britain, Health Services Accessibility, Humans, Male, Middle Aged, Nurse's Practice Patterns, Patient Care Planning, Patient Education as Topic, Patient-Centered Care, Primary Health Care, Program Development, Self Care
Depositing User : Diane Maxfield
Date Deposited : 19 Jul 2019 15:01
Last Modified : 19 Jul 2019 15:01

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