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Inhaled nitric oxide therapy in adult cardiac surgery

Creagh-Brown, B.C. and Evans, T.W. (2009) Inhaled nitric oxide therapy in adult cardiac surgery In: Yearbook of Intensive Care and Emergency Medicine 2009. Springer New York, pp. 511-519. ISBN 978-0-387-92277-5

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Nitric oxide (NO) is a naturally-occurring free radical that exists as a colorless and odorless gas. In biological solutions, NO is highly diffusible both in water and through biological membranes, with a half-life measured in seconds. Prior to the recognition that NO was the same molecule as an endothelium-derived relaxing factor some 20 years ago it was considered to be mainly an environmental pollutant. However, NO is now recognized as an endogenously produced vasodilator that modulates vascular tone and, thereby, regulates systemic and pulmonary blood flow. It has also been found to have diverse roles throughout mammalian physiology, including neurotransmission and host defense.

Item Type: Book Section
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
Evans, T.W.
Date : 2009
DOI : 10.1007/978-0-387-92278-2_48
Related URLs :
Depositing User : Clive Harris
Date Deposited : 26 Mar 2019 11:22
Last Modified : 26 Mar 2019 11:22

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