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Introduction to special issue on Polyphenols and Health

Oteiza, Patricia I. and Heiss, Christian (2018) Introduction to special issue on Polyphenols and Health Archives of Biochemistry and Biophysics, 652. pp. 1-2.

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The understanding of the beneficial effects of plant bioactives on human health is of critical interest considering the already observed and proven benefits for some of them, i.e. fiber and control of glycemia, stanols mitigating hypercholesterolemia. In the field of polyphenols, and as discussed in the introductory review [1], research has grown exponentially in the last 25 years, at a faster rate than for other bioactives. Although there is a significant lack of information on major aspects of the relevance of dietary polyphenols on human health, the field has advanced significantly. Thus, there is considerably more information on the absorption, distribution, metabolism, and excretion (ADME) of polyphenols in healthy humans [2]. In particular, it is important to consider that humans can have major differences in metabolizing capacity given individual differences in intestinal microbiota and in the genes involved in ADME [2,3]. Characterization of polyphenol metabolism in different species (e.g. humans [2,3] and rats [4] is relevant for the evaluation of how the extensive experimental research originated in rodents can be extrapolated to the actions of individual polyphenols in humans.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
Oteiza, Patricia I.
Date : 31 May 2018
DOI : 10.1016/
Copyright Disclaimer : © 2018 Published by Elsevier Inc.
Depositing User : Clive Harris
Date Deposited : 29 Aug 2018 11:02
Last Modified : 31 Oct 2019 15:41

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