Fabrication and Optimization of Fiber-Based Lithium Sensor: A Step towards Wearable Sensors for Lithium Drug Monitoring in Interstitial Fluid
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Sweilam, Mona N., Varcoe, John R. and Crean, Carol (2018) Fabrication and Optimization of Fiber-Based Lithium Sensor: A Step towards Wearable Sensors for Lithium Drug Monitoring in Interstitial Fluid ACS Sensors, 3 (9). pp. 1802-1810.
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Fabrication and Optimization of Fiber-Based Lithium Sensor REVISED MANUSCRIPT.docx - Accepted version Manuscript Download (1MB) |
Official URL: https://doi.org/10.1021/acssensors.8b00528
Abstract
A miniaturized, flexible fiber-based lithium sensor was fabricated from low-cost cotton using a simple, repeatable dip-coating technique. This lithium sensor is highly suited for ready-to-use wearable applications and can be used directly without the preconditioning steps normally required with traditional ion-selective electrodes. The sensor has a stable, rapid and accurate response over a wide Li+ concentration range that spans over the clinically effective and the toxic concentration limits for lithium in human serum. The sensor is selective to Li+ in human plasma even in the presence of a high concentration of Na+ ions. This novel sensor concept represents a significant advance in wearable sensor technology which will target lithium drug monitoring from under the skin.
| Item Type: | Article | ||||||||||||
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| Divisions : | Faculty of Engineering and Physical Sciences > Chemistry | ||||||||||||
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| Date : | 10 August 2018 | ||||||||||||
| Funders : | Engineering and Physical Sciences Research Council (EPSRC) | ||||||||||||
| DOI : | 10.1021/acssensors.8b00528 | ||||||||||||
| Grant Title : | High Spec Raman Spectrometer Regional Facility | ||||||||||||
| Copyright Disclaimer : | Copyright © 2018 American Chemical Society | ||||||||||||
| Uncontrolled Keywords : | Electrochemical analysis; Wearable sensor; Ion-selective electrode; Fiber; Conductive cotton; Lithium sensor; Non-invasive monitoring | ||||||||||||
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| Depositing User : | Clive Harris | ||||||||||||
| Date Deposited : | 13 Aug 2018 01:08 | ||||||||||||
| Last Modified : | 11 Aug 2019 02:08 | ||||||||||||
| URI: | http://epubs.surrey.ac.uk/id/eprint/848900 |
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