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Refractive index tomography of turbid media by bifocal optical coherence refractometry

Zvyagin, A.V., Silva, K.K.M.B.D., Alexandrov, S.A., Hillman, T.R., Armstrong, J.J., Tsuzuki, T. and Sampson, David (2003) Refractive index tomography of turbid media by bifocal optical coherence refractometry Optics Express, 11 (25). pp. 3503-3517.

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We demonstrate tomographic imaging of the refractive index of turbid media using bifocal optical coherence refractometry (BOCR). The technique, which is a variant of optical coherence tomography, is based on the measurement of the optical pathlength difference between two foci simultaneously present in a medium of interest. We describe a new method to axially shift the bifocal optical pathlength that avoids the need to physically relocate the objective lens or the sample during an axial scan, and present an experimental realization based on an adaptive liquid-crystal lens. We present experimental results, including video clips, which demonstrate refractive index tomography of a range of turbid liquid phantoms, as well as of human skin in vivo.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences
Faculty of Health and Medical Sciences
Authors :
Zvyagin, A.V.
Silva, K.K.M.B.D.
Alexandrov, S.A.
Hillman, T.R.
Armstrong, J.J.
Tsuzuki, T.
Date : 2003
DOI : 10.1364/OE.11.003503
Uncontrolled Keywords : Diffraction gratings, Lenses, Liquid crystals, Optical fibers, Refraction, Refractive index, Skin, Tissue, Confocal microscopy, Optical coherence tomography, Turbid media, Tomography
Depositing User : Maria Rodriguez-Marquez
Date Deposited : 12 Jun 2018 10:08
Last Modified : 06 Jul 2019 05:25

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