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High-sensitivity anastigmatic imaging needle for optical coherence tomography

Scolaro, L., Lorenser, D., McLaughlin, R.A., Quirk, B.C., Kirk, R.W. and Sampson, D.D. (2012) High-sensitivity anastigmatic imaging needle for optical coherence tomography Optics Letters, 37 (24). pp. 5247-5249.

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We present a high-optical-quality imaging needle for optical coherence tomography (OCT) that achieves sensitivity and resolution comparable to conventional free-space OCT sample arms. The side-viewing needle design utilizes total internal reflection from an angle-polished fiber tip, encased in a glass microcapillary. Fusion of the capillary to the fiber provides a robust, optical-quality output window. The needle's focusing optics are based on an astigmatism-free design, which exploits the "focal shift" phenomenon for focused Gaussian beams to achieve equal working distances (WDs) for both axes. We present a fabricated needle with a WD ratio of 0.98 for imaging in an aqueous environment. Our needle achieves the highest sensitivity of currently reported OCT imaging needles (112 dB), and we demonstrate its performance by superficial imaging of human skin and 3D volumetric imaging within a biological sample.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences
Faculty of Health and Medical Sciences
Authors :
Scolaro, L.
Lorenser, D.
McLaughlin, R.A.
Quirk, B.C.
Kirk, R.W.
Date : 2012
DOI : 10.1364/OL.37.005247
Uncontrolled Keywords : Aqueous environment, Biological samples, Fiber tip, Focal shifts, Focused Gaussian beam, Focusing optics, High-sensitivity, Human skin, Micro-capillaries, OCT imaging, Output window, Total internal reflections, Volumetric Imaging, Working distances, Gaussian beams, Needles, Refractive index, Optical tomography, article, artifact, equipment, equipment design, equipment failure, image enhancement, needle, optical coherence tomography, optical instrumentation, reproducibility, sensitivity and specificity, Artifacts, Equipment Design, Equipment Failure Analysis, Image Enhancement, Lenses, Needles, Reproducibility of Results, Sensitivity and Specificity, Tomography, Optical Coherence
Depositing User : Maria Rodriguez-Marquez
Date Deposited : 05 Jun 2018 15:15
Last Modified : 19 Sep 2018 11:32

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