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A review of optical coherence elastography: Fundamentals, techniques and prospects

Kennedy, B.F., Kennedy, K.M. and Sampson, David (2014) A review of optical coherence elastography: Fundamentals, techniques and prospects IEEE Journal on Selected Topics in Quantum Electronics, 20 (2).

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In optical coherence elastography, images are formed by mapping a mechanical property of tissue. Such images, known as elastograms, are formed on the microscale, intermediate between that of cells and whole organs. Optical coherence elastography holds great promise for detecting and monitoring the altered mechanical properties that accompany many clinical conditions and pathologies, particularly in cancer, cardiovascular disease and eye disease. In this review, we first consider how the mechanical properties of tissue are linked with tissue function and pathology. We then describe currently prominent optical coherence elastography techniques, with emphasis on the methods of mechanical loading and displacement estimation. We highlight the sensitivity to microstrain deformations at tens of micrometer resolution. Throughout, optical coherence elastography is considered in the context of other elastography methods, mainly ultrasound elastography and magnetic resonance elastography. This context serves to highlight its advantages, early stage of development of applications, and strong prospects for future impact.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences
Faculty of Health and Medical Sciences
Authors :
Kennedy, B.F.
Kennedy, K.M.
Date : 2014
DOI : 10.1109/JSTQE.2013.2291445
Uncontrolled Keywords : elastography, mechanical properties, optical coherence elastography, optical coherence tomography, Tissue mechanics, Cardio-vascular disease, Clinical conditions, Displacement estimation, Elastography, Magnetic resonance elastography, Optical coherence elastography, Tissue mechanics, Ultrasound elastography, Degrees of freedom (mechanics), Diseases, Magnetic resonance, Mechanical properties, Medical imaging, Optical tomography, Pathology, Tissue, Biomechanics
Depositing User : Maria Rodriguez-Marquez
Date Deposited : 05 Jun 2018 08:58
Last Modified : 19 Sep 2018 11:32

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