Optical palpation: Optical coherence tomography-based tactile imaging using a compliant sensor

Kennedy, K.M., Es'haghian, S., Chin, L., McLaughlin, R.A., Sampson, David and Kennedy, B.F. (2014) Optical palpation: Optical coherence tomography-based tactile imaging using a compliant sensor Optics Letters, 39 (10). pp. 3014-3017.

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Abstract

We present optical palpation, a tactile imaging technique for mapping micrometer- to millimeter-scale mechanical variations in soft tissue. In optical palpation, a stress sensor consisting of translucent, compliant silicone with known stress-strain behavior is placed on the tissue surface and a compressive load is applied. Optical coherence tomography (OCT) is used to measure the local strain in the sensor, from which the local stress at the sample surface is calculated and mapped onto an image. We present results in tissue-mimicking phantoms, demonstrating the detection of a feature embedded 4.7 mm below the sample surface, well beyond the depth range of OCT. We demonstrate the use of optical palpation to delineate the boundary of a region of tumor in freshly excised human breast tissue, validated against histopathology.

Item Type:	Article
Divisions :	Faculty of Engineering and Physical Sciences Faculty of Health and Medical Sciences
Authors :	Name Email ORCID Kennedy, K.M. Es'haghian, S. Chin, L. McLaughlin, R.A. Sampson, David d.sampson@surrey.ac.uk Kennedy, B.F.
Date :	2014
DOI :	10.1364/OL.39.003014
Uncontrolled Keywords :	Imaging techniques, Optical tomography, Sensors, Silicones, Compressive loads, Human breast tissue, Mechanical variations, Millimeter-scale, Sample surface, Stress-strain behaviors, Tissue mimicking phantom, Tissue surface, Tissue, Breast Neoplasms, compressive strength, device failure analysis, devices, elastography, equipment design, female, hardness, human, manometry, mechanical stress, optical coherence tomography, palpation, pathophysiology, tensile strength, touch, transducer, Young modulus, Breast Neoplasms, Compressive Strength, Elastic Modulus, Elasticity Imaging Techniques, Equipment Design, Equipment Failure Analysis, Female, Hardness, Humans, Manometry, Palpation, Stress, Mechanical, Tensile Strength, Tomography, Optical Coherence, Touch, Transducers
Depositing User :	Maria Rodriguez-Marquez
Date Deposited :	05 Jun 2018 09:06
Last Modified :	19 Sep 2018 11:32
URI:	http://epubs.surrey.ac.uk/id/eprint/846796

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