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DynAMITe: A prototype large area CMOS APS for breast cancer diagnosis using x-ray diffraction measurements

Konstantinidis, A, Anaxagoras, T, Esposito, M, Allinson, N and Speller, R (2012) DynAMITe: A prototype large area CMOS APS for breast cancer diagnosis using x-ray diffraction measurements Progress in Biomedical Optics and Imaging - Proceedings of SPIE, 8313.

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X-ray diffraction studies are used to identify specific materials. Several laboratory-based x-ray diffraction studies were made for breast cancer diagnosis. Ideally a large area, low noise, linear and wide dynamic range digital x-ray detector is required to perform x-ray diffraction measurements. Recently, digital detectors based on Complementary Metal-Oxide- Semiconductor (CMOS) Active Pixel Sensor (APS) technology have been used in x-ray diffraction studies. Two APS detectors, namely Vanilla and Large Area Sensor (LAS), were developed by the Multidimensional Integrated Intelligent Imaging (MI-3) consortium to cover a range of scientific applications including x-ray diffraction. The MI-3 Plus consortium developed a novel large area APS, named as Dynamically Adjustable Medical Imaging Technology (DynAMITe), to combine the key characteristics of Vanilla and LAS with a number of extra features. The active area (12.8 × 13.1 cm 2) of DynaMITe offers the ability of angle dispersive x-ray diffraction (ADXRD). The current study demonstrates the feasibility of using DynaMITe for breast cancer diagnosis by identifying six breast-equivalent plastics. Further work will be done to optimize the system in order to perform ADXRD for identification of suspicious areas of breast tissue following a conventional mammogram taken with the same sensor. © 2012 Copyright Society of Photo-Optical Instrumentation Engineers (SPIE).

Item Type: Article
Divisions : Surrey research (other units)
Authors :
Anaxagoras, T
Allinson, N
Speller, R
Date : 4 May 2012
DOI : 10.1117/12.911541
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 12:25
Last Modified : 24 Jan 2020 22:13

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