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Killing two birds with one stone: a case of GIST and supervening CML

Mehta, VR, Khan, U, Hoang, U and Rachshtut, M (2015) Killing two birds with one stone: a case of GIST and supervening CML BMJ Case Reports.

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A 50-year-old patient who presented with abdominal pain was found to have a suspicious 8×6×9 cm mass in the left upper abdomen on imaging. A complete surgical resection of the mass was performed subsequently and pathology revealed a gastrointestinal stromal tumour. The patient was started on adjuvant Imatinib following the resection. Four years later, reimaging demonstrated no evidence of disease and adjuvant therapy was discontinued. Nine months following discontinuation of Imatinib, routine blood work revealed marked leucocytosis. Further work up including peripheral smear and bone marrow biopsy showed findings consistent with chronic myelogenous leucaemia. Imatinib was restarted and the patient's white cell counts returned to normal range within a month.

Item Type: Article
Subjects : Medical Science
Divisions : Surrey research (other units)
Authors :
Mehta, VR
Khan, U
Rachshtut, M
Date : 14 October 2015
DOI : 10.1136/bcr-2015-211698
Copyright Disclaimer : Copyright © 2015 by the BMJ Publishing Group Ltd. All rights reserved
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:47
Last Modified : 24 Jan 2020 20:03

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