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Developmental outcomes of 3,4-methylenedioxymethamphetamine (ecstasy)-exposed infants in the UK.

Singer, LT, Moore, DG, Min, MO, Goodwin, J, Turner, JJ, Fulton, S and Parrott, AC (2015) Developmental outcomes of 3,4-methylenedioxymethamphetamine (ecstasy)-exposed infants in the UK. Hum Psychopharmacol, 30 (4). pp. 290-294.

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OBJECTIVE: This paper aims to review findings from a longitudinal study of prenatal methylenedioxymethamphetamine (MDMA, "ecstasy") on infant development. METHODS: In a prospective, longitudinal cohort design, we followed 28 MDMA-exposed and 68 non-MDMA-exposed infants from birth to 2 years of age. Women recruited voluntarily into a study of recreational drug use during pregnancy were interviewed to obtain type, frequency, and amount of recreational drug use. Their children were followed for a 2-year period after birth. A large number of drug and environmental covariates were controlled. Infants were seen at 1, 4, 12, 18, and 24 months using standardized normative tests of mental and motor development. RESULTS: There were no differences between MDMA-exposed and non-MDMA-exposed infants at birth except that MDMA-exposed infants were more likely to be male. Motor delays were evident in MDMA infants at each age and amount of MDMA exposure predicted motor deficits at 12 months in a dose-dependent fashion. CONCLUSIONS: Prenatal MDMA exposure is related to fine and gross motor delays in the first 2 years of life. Follow-up studies are needed to determine long-term effects.

Item Type: Article
Divisions : Surrey research (other units)
Authors :
Singer, LT
Min, MO
Goodwin, J
Turner, JJ
Fulton, S
Parrott, AC
Date : July 2015
DOI : 10.1002/hup.2459
Uncontrolled Keywords : MDMA, ecstasy, infant development, methylenedioxymethamphetamine, motor, prenatal, Adult, Age Factors, Child Development, Developmental Disabilities, Female, Great Britain, Hallucinogens, Humans, Infant, Infant, Newborn, Male, N-Methyl-3,4-methylenedioxyamphetamine, Pregnancy, Prenatal Exposure Delayed Effects
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:34
Last Modified : 24 Jan 2020 19:35

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