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Primary Hyperparathyroidism

Bacon, NJ (2013) Primary Hyperparathyroidism In: Small Animal Soft Tissue Surgery. UNSPECIFIED, pp. 1-16. ISBN 9781118997505

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© 2013 John Wiley & Sons, Ltd.The parathyroid glands in dogs and cats are tan-colored ovoid structures closely associated with each thyroid gland. Parathyroid hormone (PTH) release is controlled by calcium receptors on the chief cells in the parathyroid glands in response to hypocalcemia. PTH has a short half-life (3-5 min) in serum and so a steady rate of secretion is necessary to maintain serum PTH concentrations. Natural variations in PTH concentration occur in healthy dogs. Exploratory surgery with parathyroidectomy in dogs with primary hyperparathyroidism serves as both a diagnostic test and definitive therapy. Surgery should be advocated to reduce the risk of urolithiasis and urinary tract infection, as well as improving the clinical signs seen with hypercalcemia such as polydipsia, polyuria, weakness, and decreased appetite. Surgical excision alone is the most widely performed treatment for primary hyperparathyroidism and a cure rate of 94% is reported if all autonomously functioning parathyroid tissue is removed.

Item Type: Book Section
Divisions : Surrey research (other units)
Authors :
Date : 4 January 2013
DOI : 10.1002/9781118997505.ch1
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:31
Last Modified : 23 Jan 2020 16:05

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