African swine fever and classical swine fever: a review of the pathogenesis.

Gómez-Villamandos, JC, Carrasco, L, Bautista, MJ, Sierra, MA, Quezada, M, Hervas, J, Chacón, MDEL, Ruiz-Villamor, E, Salguero, FJ, Sónchez-Cordón, PJ et al, Romanini, S, Núñez, A, Mekonen, T, Méndez, A and Jover, A (2003) African swine fever and classical swine fever: a review of the pathogenesis. Dtsch Tierarztl Wochenschr, 110 (4). pp. 165-169.

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Abstract

This paper describes major pathogenetic mechanisms of African and Classical Swine Fever virus infections. The interactions between both viruses and the monocyte-macrophage-system result in the release of mediator molecules, which are important for the further progression of the diseases. The causes of the thrombocytopenia and the mechanisms of the haemorrhages, which are characteristic in both infections, are described. Apoptotic cell death is regarded as the predominant cause of lymphopenia in both virus infections.

Item Type:	Article
Divisions :	Surrey research (other units)
Authors :	Gómez-Villamandos, JC, Carrasco, L, Bautista, MJ, Sierra, MA, Quezada, M, Hervas, J, Chacón, MDEL, Ruiz-Villamor, E, Salguero, FJ, Sónchez-Cordón, PJ, Romanini, S, Núñez, A, Mekonen, T, Méndez, A and Jover, A
Date :	April 2003
Uncontrolled Keywords :	African Swine Fever, African Swine Fever Virus, Animals, Apoptosis, Classical Swine Fever, Classical swine fever virus, Cytokines, Macrophages, Monocytes, Swine
Related URLs :	Author
Depositing User :	Symplectic Elements
Date Deposited :	17 May 2017 10:08
Last Modified :	24 Jan 2020 18:33
URI:	http://epubs.surrey.ac.uk/id/eprint/826568

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