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Structural and functional characterisation of cardiac fibroblasts.

Camelliti, P, Borg, TK and Kohl, P (2005) Structural and functional characterisation of cardiac fibroblasts. Cardiovasc Res, 65 (1). pp. 40-51.

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Cardiac fibroblasts form one of the largest cell populations, in terms of cell numbers, in the heart. They contribute to structural, biochemical, mechanical and electrical properties of the myocardium. Nonetheless, they are often disregarded by in vivo and in vitro studies into cardiac function. This review summarizes our understanding of fibroblast origin and identity, their structural organization and role in myocardial architecture, as well as functional aspects related to cell signalling and electro-mechanical function in the heart.

Item Type: Article
Divisions : Surrey research (other units)
Authors :
Borg, TK
Kohl, P
Date : 1 January 2005
DOI : 10.1016/j.cardiores.2004.08.020
Uncontrolled Keywords : Animals, Electrophysiology, Fibroblasts, Gap Junctions, Humans, Myocardial Contraction, Myocardium, Signal Transduction
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 10:00
Last Modified : 24 Jan 2020 18:15

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