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Molecular Analysis in Factor XI Deficiency.

Johnson, KM and McVey, JH (1999) Molecular Analysis in Factor XI Deficiency. In: UNSPECIFIED UNSPECIFIED, pp. 211-221.

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Factor XI (FXI) is the zymogen precursor of an active serine protease that participates in the contact phase of coagulation. Synthesized in the liver, it circulates in the plasma in a noncovalent complex with high molecular weight kininogen (1) at a normal concentration of 5 μg/mL. (For clinical purposes, the normal range is defined as 50-150 U/dL) (2). FXI circulates as a homodimeric glycoprotein with a mass of 160 kDa.

Item Type: Book Section
Divisions : Surrey research (other units)
Authors :
Johnson, KM
Date : 1999
DOI : 10.1385/1-59259-248-1:211
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:58
Last Modified : 23 Jan 2020 15:51

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