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Pathophysiology and treatment of neuropathic pain associated with syringomyelia.

Rusbridge, C and Jeffery, ND (2008) Pathophysiology and treatment of neuropathic pain associated with syringomyelia. Vet J, 175 (2). pp. 164-172.

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The pain behaviour expressed by dogs with syringomyelia suggests that they experience neuropathic pain, probably due to disordered neural processing in the damaged dorsal horn. As such it is likely that conventional analgesic medication will be ineffective. In this review, physiological and pathological pain processing through the dorsal horn is summarised and mechanisms by which syringomyelia could result in a persistent pain state are discussed. Finally, current knowledge regarding treatment of Chiari malformation and syringomyelia is reviewed and possible drugs which may give improved pain relief in affected dogs are discussed.

Item Type: Article
Divisions : Surrey research (other units)
Authors :
Jeffery, ND
Date : February 2008
DOI : 10.1016/j.tvjl.2006.12.007
Uncontrolled Keywords : Animals, Dog Diseases, Dogs, Pain, Pain Management, Syringomyelia
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:54
Last Modified : 24 Jan 2020 17:57

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