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The basis of differential responses to folic acid supplementation.

Cotlarciuc, I, Andrew, T, Dew, T, Clement, G, Gill, R, Surdulescu, G, Sherwood, R and Ahmadi, KR (2011) The basis of differential responses to folic acid supplementation. J Nutrigenet Nutrigenomics, 4 (2). pp. 99-109.

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Elevated levels of total homocysteine (tHcy) are associated with an increased risk of many common diseases. Supplementation with folic acid has been shown to significantly reduce tHcy levels. We used the classical twin model to partition the variability in changes in plasma tHcy levels through folic acid supplementation into genetic, environmental, and confounding epidemiological factors.

Item Type: Article
Divisions : Surrey research (other units)
Authors :
Cotlarciuc, I
Andrew, T
Dew, T
Clement, G
Gill, R
Surdulescu, G
Sherwood, R
Date : 2011
DOI : 10.1159/000327768
Uncontrolled Keywords : Aged, Aged, 80 and over, Female, Folic Acid, Genetic Predisposition to Disease, Homocysteine, Humans, Hyperhomocysteinemia, Methylenetetrahydrofolate Reductase (NADPH2), Middle Aged, Models, Genetic, Nutrigenomics, Polymorphism, Single Nucleotide, Twins, Dizygotic, Twins, Monozygotic, Vitamin B 12
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:48
Last Modified : 24 Jan 2020 17:41

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