University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Genetic epidemiology of induced CYP3A4 activity.

Rahmioglu, N, Heaton, J, Clement, G, Gill, R, Surdulescu, G, Zlobecka, K, Hodgkiss, D, Ma, Y, Hider, RC, Smith, NW and Ahmadi, KR (2011) Genetic epidemiology of induced CYP3A4 activity. Pharmacogenet Genomics, 21 (10). pp. 642-651.

Full text not available from this repository.


The cytochrome P450 3A4 (CYP3A4) enzyme is implicated in the metabolism of more than 50% of all prescribed medications and its activity - including induced or inhibited activity - is deemed to be a crucial determinant of interindividual variability in drug disposition, poor therapeutic efficacy, and adverse response to medication.

Item Type: Article
Divisions : Surrey research (other units)
Authors :
Rahmioglu, N
Heaton, J
Clement, G
Gill, R
Surdulescu, G
Zlobecka, K
Hodgkiss, D
Ma, Y
Hider, RC
Smith, NW
Date : October 2011
DOI : 10.1097/FPC.0b013e3283498ecf
Uncontrolled Keywords : Aged, Aged, 80 and over, Alcohol Drinking, Biomarkers, Pharmacological, Body Mass Index, Cytochrome P-450 CYP3A, Female, Humans, Hypericum, Middle Aged, Models, Genetic, Plant Extracts, Questionnaires, Quinidine, Quinine, Smoking
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:48
Last Modified : 24 Jan 2020 17:41

Actions (login required)

View Item View Item


Downloads per month over past year

Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800