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Measurement of melatonin and 6-sulphatoxymelatonin.

Middleton, B (2006) Measurement of melatonin and 6-sulphatoxymelatonin. Methods Mol Biol, 324. pp. 235-254.

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Melatonin and its major metabolite, 6-sulphatoxymelatonin, can routinely be measured by RIA or ELISA. Plasma, serum or saliva samples maybe used for melatonin measurement and urine for the metabolite. Melatonin is a hormone produced by the pineal gland witha clear circadian rhythm giving low levels by day and a peak during the night in normally entrained individuals. The timing of sample collection for measurement is therefore crucial. Melatonin levels are primarily assessed to determine the timing of an individual's internal body clock and therefore indicate any misalignment to the 24 h day.

Item Type: Article
Divisions : Surrey research (other units)
Authors :
Date : 2006
DOI : 10.1385/1-59259-986-9:235
Uncontrolled Keywords : Animals, Enzyme-Linked Immunosorbent Assay, Humans, Melatonin, Radioimmunoassay, Reagent Kits, Diagnostic, Saliva
Related URLs :
Depositing User : Symplectic Elements
Date Deposited : 17 May 2017 09:06
Last Modified : 24 Jan 2020 16:02

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