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The New Designer Drug Wave: A Clinical, Toxicological, and Legal Analysis

Abbott, R., M.D., J.D., and Smith, DE (2015) The New Designer Drug Wave: A Clinical, Toxicological, and Legal Analysis Journal of Psychoactive Drugs, 47 (5). pp. 368-371.

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This article reviews clinical, toxicological, and legal issues related to designer drug abuse, with a focus on synthetic cathinones (bath salts). Synthetic cathinones are amphetamine-type central nervous system (CNS) stimulants that produce similar effects to amphetamine. Like amphetamine, synthetic cathinones can also result in neurological and cardiovascular side-effects consistent with sympathomimetic toxicity. The differential for a patient presenting with the signs and symptoms of synthetic cathinone toxicity is broad, and laboratory testing for synthetic cathinones is of limited value in acute management. If a diagnosis of cathinone-induced delirium is suspected, treatment efforts should focus on controlling agitation and then treating medical complications such as metabolic acidosis. Physicians should be aware of these new drugs, not only to optimally treat patients, but also to raise awareness of the dangers of designer drug use through patient counseling and community outreach programs. © Taylor & Francis Group, LLC.

Item Type: Article
Subjects : Law
Divisions : Surrey research (other units)
Authors : Abbott, R., M.D., J.D., and Smith, DE
Date : 18 November 2015
DOI : 10.1080/02791072.2015.1094591
Copyright Disclaimer : Copyright © Taylor & Francis Group, LLC
Uncontrolled Keywords : amphetamine, bath salts, psychoactive, stimulants, toxicity, 3,4 methylenedioxymethamphetamine, amphetamine, cathinone, designer drug, alkaloid, amphetamine derivative, central stimulant agent, designer drug, behavior assessment, catatonia, clinical assessment, cross reaction, drug abuse, fever, human, hyperthermia, immunoassay, legal aspect, metabolic acidosis, patient counseling, public health, Review, rhabdomyolysis, toxicology, chemically induced, delirium, drug legislation, synthesis, Alkaloids, Amphetamines, Central Nervous System Stimulants, Delirium, Designer Drugs, Humans, Legislation, Drug
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Depositing User : Symplectic Elements
Date Deposited : 16 May 2017 15:37
Last Modified : 24 Jan 2020 15:07

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