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Diaphoresis and abdominal pain caused by extra-adrenal paraganglionomas

Lee, L, Sung, WI, Akhtar, MM and Whyte, MB (2012) Diaphoresis and abdominal pain caused by extra-adrenal paraganglionomas [Report]

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A 63-year-old lady presented with suprapelvic pain, weight loss and night sweats. On examination, she was noted to be hypertensive with a distended abdomen. Imaging (CT) revealed a 9.5 cm retroperitoneal mass with a high degree of vascularity and necrotic centre. The patient’s urinary and plasma catecholamines were significantly raised and subsequent radio-isotope scan suggested the tumour was likely to be of a neuroendocrine nature. A diagnosis of a malignant paraganglioma was made. Malignant paragangliomas derive from sympathetic tissue and secrete catecholamines. Diagnostic uncertainty might lead to biopsy of tumour but this carries a high-risk of catecholamine-induced complications such as hypertensive crisis, cardiac arrhythmias and cardiac ischaemia and must be avoided.

Item Type: Report
Subjects : Nutrition
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine > Department of Nutritional Sciences
Authors :
Lee, L
Sung, WI
Akhtar, MM
Whyte, MB
Date : 3 July 2012
DOI : 10.1136/bcr.01.2012.5649
Copyright Disclaimer : Copyright © 2016 by the BMJ Publishing Group Ltd. All rights reserved.
Depositing User : Symplectic Elements
Date Deposited : 19 Oct 2016 08:03
Last Modified : 31 Oct 2017 18:48

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