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Clinical diagnostics for homocysteine: a rogue amino acid?

Newton, LA, Sandhu, K, Livingstone, C, Leslie, R and Davis, J (2010) Clinical diagnostics for homocysteine: a rogue amino acid? Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare, 10 (4). pp. 489-500.

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Homocysteine has gathered considerable interest in recent years after being implicated in the pathogenesis of various clinical conditions. It has been an elusive target with many conflicting studies casting some confusion over its significance, and much more needs to be done to ascertain its pathophysiological role--especially with respect to regimes aimed at lowering its plasma concentration. Central to this is the development of robust analytical strategies for its determination. This review summarizes the clinical relevance of homocysteine as a diagnostic marker of disease and explores and critically assesses the detection methods that have been developed.

Item Type: Article
Subjects : Biosciences
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
Newton, LA
Sandhu, K
Livingstone, C
Leslie, R
Davis, J
Date : May 2010
DOI : 10.1586/erm.10.19
Uncontrolled Keywords : Animals, Avitaminosis, Cardiovascular Diseases, Female, Folic Acid, Homocysteine, Humans, Mental Disorders, Molecular Structure, Neurodegenerative Diseases, Oxidation-Reduction, Pathology, Molecular, Pregnancy, Pregnancy Complications
Related URLs :
Additional Information : Item not available from this repository
Depositing User : Symplectic Elements
Date Deposited : 15 Sep 2016 13:20
Last Modified : 31 Oct 2017 18:43

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