University of Surrey

Test tubes in the lab Research in the ATI Dance Research

Non-PEG-derived polyethers as solid supports. 1. Synthesis, swelling studies, and functionalization

Cavalli, G, Steinke, JHG, Shooter, AG and Pears, DA (2003) Non-PEG-derived polyethers as solid supports. 1. Synthesis, swelling studies, and functionalization Journal of Combinatorial Chemistry, 5 (5). pp. 637-644.

[img] Text
Restricted to Repository staff only

Download (310kB)

Download (172kB)


Novel non-PEG derived polyether resins, coined SLURPS (superior liquid-uptake resins for polymer-supported synthesis), were synthesized by cationic polymerization of vinyl ethers. A functional resin was prepared with excellent control over loading levels. A sequence of synthetic transformations involving the introduction of a Wang linker followed by Mitsunobu functionalization chemistry and cleavage of the bound substrate proceeded quantitatively. These new polymers combine outstanding swelling performance in a wide range of solvents with high chemical stability and tunable loading levels up to 8.5 mmol/g. This combination of desirable features sets them apart from other polymer supports and, in particular, other polyether resins currently investigated for combinatorial chemistry.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Chemistry
Authors :
Cavalli, G
Steinke, JHG
Shooter, AG
Pears, DA
Date : September 2003
DOI : 10.1021/cc0200686
Additional Information : This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Combinatorial Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher.To access the final edited and published work see
Depositing User : Symplectic Elements
Date Deposited : 11 Sep 2013 08:01
Last Modified : 31 Oct 2017 15:12

Actions (login required)

View Item View Item


Downloads per month over past year

Information about this web site

© The University of Surrey, Guildford, Surrey, GU2 7XH, United Kingdom.
+44 (0)1483 300800