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Number of items: 46.

Fisher, C, Coleman, T and Plant, N (2011) Cross-species characterisation of intestinal drug transporters

Gee, RH, Plant, NJ, Johnston, JD and Plant, KE (2011) Differential sensitivity to toxicity of statins: A comparison of liver and muscle cell lines

Villela, I, Heidenreich, B, Cheema, M, di Martino, T, Samson, LD and Meira, LB (2011) Dissecting the mechanism of DNA damage induced photoreceptor cell death TOXICOLOGY, 290 (2-3). p. 143.

Yimthaing, S, Plant, N and Plant, K (2011) Regulation of nuclear import pathways by vitamin D signalling: Potential biological implications

Gee, RH, Plant, NJ, Johnston, JD and Plant, KE (2010) The effects of time of treatment on statin muscle toxicity: Preliminary characterization of a human muscle cell line In: 2010 Annual Spring Meeting of the British-Toxicological-Society, 2010-03-28 - 2010-03-31, Herriot Watt Univ, Edinburgh, ENGLAND.

Konsue, N and Ioannides, C (2010) Modulation of carcinogen-metabolising cytochromes P450 in human liver by the chemopreventive phytochemical phenethyl isothiocyanate, a constituent of cruciferous vegetables TOXICOLOGY, 268 (3). pp. 184-190.

Sanat, F, Howe, K, Coleman, T, Thumser, A and Plant, N (2009) Impact of transporter-mediated uptake on statin-induced gene expression in human Huh7 cells In: Annual Congress of the British-Toxicological-Society, 2009-03-22 - 2009-03-25, Univ Warwick, Coventry, ENGLAND.

Fisher, C, Coleman, T and Plant, N (2009) Phylogenetic analysis of the ATP-binding cassette super-family: Implications for the development of multiple drug resistance phenotype In: Annual Congress of the British-Toxicological-Society, 2009-03-22 - 2009-03-25, Univ Warwick, Coventry, ENGLAND.

Plant, N (2008) Can systems toxicology identify common biomarkers of non-genotoxic carcinogenesis? TOXICOLOGY, 254 (3). pp. 164-169.

Cheema, MS, Gibson, GG, Plant, N and Plant, KE (2008) The human karyopherin alpha 2 promoter is responsive to oxidative stress In: Annual Congress of the British-Toxicological-Society, 2008-04-06 - 2008-04-09, Univ Surrey, Guildford, ENGLAND.

Hanlon, N, Coldham, N, Sauer, MJ and Ioannides, C (2008) Up-regulation of the CYP1 family in rat and human liver by the aliphatic isothiocyanates erucin and sulforaphane TOXICOLOGY, 252 (1-3). pp. 92-98.

Shen, T, Zhu, Q-X, Yang, S, Wu, C-H, Zhang, H-F, Zhou, C-F and Zhang, X-J (2008) Trichloroethylene induced cutaneous irritation in BALB/c hairless mice: Histopathological changes and oxidative damage TOXICOLOGY, 248 (2-3). pp. 113-120.

Konsue, N and Ioannides, C (2007) Chemoprevention effect of phenethyl isothiocyanate In: Annual Congress of the British-Toxicological-Society, 2007-04-15 - 2007-04-18, Univ Surrey, Guildford, ENGLAND.

Huebner, Y, Mulhall, H, Hoettges, KF, Kass, GEN, Ogin, SL and Hughes, MP (2007) Dielectrophoresis: A new in vitro approach to measure drug-induced cytotoxicity In: Annual Congress of the British-Toxicological-Society, 2007-04-15 - 2007-04-18, Univ Surrey, Guildford, ENGLAND.

Umachandran, M and Ioannides, C (2007) Interactions between polycyclic aromatic hydrocarbons in precision-cut rat lung slices In: Annual Congress of the British-Toxicological-Society, 2007-04-15 - 2007-04-18, Univ Surrey, Guildford, ENGLAND.

Arya, N, Ioannides, C, Kuhnert, N, Kirkpatrick, J and Stevenson, D (2007) Metabolism of 2-amino-3-methylimidazol [4,5,f]quinoline by precision-cut rat liver slices In: Annual Congress of the British-Toxicological-Society, 2007-04-15 - 2007-04-18, Univ Surrey, Guildford, ENGLAND.

Cheema, MS, Plant, NJ, Gibson, GG and Plant, KE (2007) Response of nuclear import factor encoding genes to xenobiotics: Analysis of the human karyopherin alpha 2 promoter In: Annual Congress of the British-Toxicological-Society, 2007-04-15 - 2007-04-18, Univ Surrey, Guildford, ENGLAND.

Pushparajah, DS, Umachandran, M, Plant, KE, Plant, N and Ioannides, C (2007) Evaluation of the precision-cut liver and lung slice systems for the study of induction of CYP1, epoxide hydrolase and glutathione S-transferase activities TOXICOLOGY, 231 (1). pp. 68-80.

Plant, K, Thumser, A and Plant, N (2006) Evolution of the fatty acid-binding protein family: An ordered increase in gene number, correlating to more refined mechanisms of lipid processing In: Joint Congress of the British-Toxicology-Society/29th Annual Meeting of the United-Kingdom-Environmental-Mutagen-Society, 2006-03-19 - 2006-03-22, Univ Warwick, Coventry, ENGLAND.

Plant, K, Brown, R, Anderson, E, Toms, N, Simecek, N, Lyon, J and Plant, N (2006) Modulation of Six1 expression by the anti-mania agents lithium chloride and sodium valproate In: Joint Congress of the British-Toxicology-Society/29th Annual Meeting of the United-Kingdom-Environmental-Mutagen-Society, 2006-03-19 - 2006-03-22, Univ Warwick, Coventry, ENGLAND.

Umachandran, M and Ioannides, C (2006) Stability of cytochromes P450 and phase II conjugation systems in precision-cut rat lung slices cultured up to 72h TOXICOLOGY, 224 (1-2). pp. 14-21.

Hanlon, N, Howarth, JA, Hinton, RH, Taylor, A and Price, SC (2006) Does the size of zinc oxide particles affect their cutaneous toxicity? In: Autumn Meeting of the British-Toxicology-Society, 2005-09-19 - 2005-09-20, Univ Bath, Bath, ENGLAND.

Plant, N (2004) Interaction networks: coordinating responses to xenobiotic exposure TOXICOLOGY, 202 (1-2). pp. 21-32.

Phillips, A, Bullock, T and Plant, N (2003) Sodium valproate induces apoptosis in the rat hepatoma cell line, FaO TOXICOLOGY, 192 (2-3). pp. 219-227.

Sivapathasundaram, S, Magnisali, P, Coldham, NG, Howells, LC, Sauer, MJ and Ioannides, C (2003) Cytochrome P450 expression and testosterone metabolism in the liver of deer TOXICOLOGY, 187 (1). pp. 49-65.

Gibson, GG, El-Sankary, W and Plant, NJ (2002) Receptor-dependent regulation of the CYP3A4 gene TOXICOLOGY, 181, PII S0300-. pp. 199-202.

Bombail, V, El-Sankary, W, Gibson, GG and Plant, N (2002) Induction of CYP3A4 gene expression by glucocorticoids occurs by a PXR-independent, as well as a PXR dependent, mechanism TOXICOLOGY, 178 (1). pp. 73-74.

Coulson, M, Gibson, GG, Plant, N, Hammond, T and Graham, M (2002) The role of a liver-testis axis in the development of Leydig cell hyperplasia TOXICOLOGY, 178 (1). pp. 51-52.

Crunkhorn, SE, Plant, N, Gibson, GG, Lord, P and Kramer, K (2001) Differential gene expression in xenobiotic-induced liver growth in rats TOXICOLOGY, 168 (1). pp. 102-103.

Swales, KE, Plant, N, Gibson, G and Ayrton, A (2001) Investigation of host cell effects on xenobiotic induction of CYP3A TOXICOLOGY, 168 (1). pp. 128-129.

Bombail, V, Plant, N and Gibson, G (2001) Mapping of protein-DNA interactions in the CYP3A4 proximal promoter TOXICOLOGY, 168 (1). pp. 129-130.

Coulson, MD, Gibson, GG, Plant, N, Hammond, T and Graham, M (2001) The role of liver-testis axis in the development of Leydig cell hyperplasia TOXICOLOGY, 168 (1). pp. 82-83.

Walton, K, Coombs, MM, Walker, R and Ioannides, C (2001) The metabolism and bioactivation of agaritine and of other mushroom hydrazines by whole mushroom homogenate and by mushroom tyrosinase TOXICOLOGY, 161 (3). pp. 165-177.

Hashemi, E, Till, C and Ioannides, C (2000) Stability of cytochrome P450 proteins in cultured precision-cut rat liver slices TOXICOLOGY, 149 (2-3). pp. 51-61.

Rockett, JC, Swales, KE, Esdaile, DJ and Gibson, GG (2000) Use of suppression-PCR subtractive hybridisation to identify genes that demonstrate altered expression in male rat and guinea pig livers following exposure to Wy-14,643, a peroxisome proliferator and non-genotoxic hepatocarcinogen TOXICOLOGY, 144 (1-3). pp. 13-29.

Marczylo, T and Ioannides, C (1999) Evidence for the presence of a microsomal NADH-dependent enzyme system that can bioactivate aromatic amines in the liver of rats and mice TOXICOLOGY, 134 (2-3). pp. 127-141.

Irizar, A and Ioannides, C (1998) Marked inhibition of hepatic cytochrome P450 activity in cholesterol-induced atherosclerosis in rabbits TOXICOLOGY, 126 (3). pp. 179-193.

Cheung, YL, Lewis, DFV, Ridd, TI, Gray, TJB and Ioannides, C (1997) Diaminonaphthalenes and related aminocompounds: Mutagenicity, CYP1A induction and interaction with the Ah receptor TOXICOLOGY, 118 (2-3). pp. 115-127.

BOYD, GW, COOMBS, MM and IOANNIDES, C (1995) CYP1 INDUCTION, BINDING TO THE HEPATIC AROMATIC HYDROCARBON RECEPTOR AND MUTAGENICITY OF A SERIES OF 11-ALKOXY CYCLOPENTA[A]PHENANTHREN-17-ONES - A STRUCTURE-ACTIVITY RELATIONSHIP TOXICOLOGY, 95 (1-3). pp. 27-35.

CHEUNG, YL, GRAY, TJB and IOANNIDES, C (1993) MUTAGENICITY OF CHRYSENE, ITS METHYL AND BENZO DERIVATIVES, AND THEIR INTERACTIONS WITH CYTOCHROMES-P-450 AND THE AH-RECEPTOR - RELEVANCE TO THEIR CARCINOGENIC POTENCY TOXICOLOGY, 81 (1). pp. 69-86.

LEIST, M, AYRTON, AD and IOANNIDES, C (1992) A CYTOSOLIC OXYGENASE ACTIVITY INVOLVED IN THE BIOACTIVATION OF 2-AMINOFLUORENE TOXICOLOGY, 71 (1-2). pp. 7-20.

LEWIS, DFV, IOANNIDES, C and PARKE, DV (1990) A RETROSPECTIVE STUDY OF THE MOLECULAR TOXICOLOGY OF BENOXAPROFEN TOXICOLOGY, 65 (1-2). pp. 33-47.

AYRTON, AD, MCFARLANE, M, WALKER, R, NEVILLE, S, COOMBS, MM and IOANNIDES, C (1990) INDUCTION OF THE P-450-I FAMILY OF PROTEINS BY POLYCYCLIC AROMATIC-HYDROCARBONS - POSSIBLE RELATIONSHIP TO THEIR CARCINOGENICITY TOXICOLOGY, 60 (1-2). pp. 173-186.

RODRIGUES, AD, WADDELL, PR, AHSING, E, MORRIS, BA, WOLF, CR and IOANNIDES, C (1988) INDUCTION OF THE RAT HEPATIC-MICROSOMAL MIXED-FUNCTION OXIDASES BY 3-IMIDAZOLE-CONTAINING ANTIFUNGAL AGENTS - SELECTIVITY FOR THE CYTOCHROME-P-450IIB AND CYTOCHROME-P-450III FAMILIES OF CYTOCHROMES-P-450 TOXICOLOGY, 50 (3). pp. 283-301.

LUM, PY, WALKER, S and IOANNIDES, C (1985) FETAL AND NEONATAL DEVELOPMENT OF CYTOCHROME-P-450 AND CYTOCHROME-P-448 CATALYZED MIXED-FUNCTION OXIDASES IN THE RAT - INDUCTION BY 3-METHYLCHOLANTHRENE TOXICOLOGY, 35 (4). pp. 307-317.

IOANNIDES, C, HALL, DE, MULDER, DE, STEELE, CM, SPICKETT, J, DELAFORGE, M and PARKE, DV (1983) A COMPARISON OF THE PROTECTIVE EFFECTS OF N-ACETYLCYSTEINE AND S-CARBOXYMETHYLCYSTEINE AGAINST PARACETAMOL-INDUCED HEPATOTOXICITY TOXICOLOGY, 28 (4). pp. 313-321.

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