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Items where Author is "Umpleby, M"

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Article

Umpleby, Margot, Shojaee-Moradie, F, Fielding, Barbara, Li, X, Marino, A, Alsini, N, Isherwood, Cheryl, Jackson, N, Ahmad, A, Stolinski, M, Lovegrove, JA, Johnsen, Sigurd, Mendis, Agampodi, Wright, John, Wilinska, ME, Hovorka, R, Bell, JD, Thomas, EL, Frost, GS and Griffin, Bruce (2017) Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets Clinical Science.

Steenson, Simon, Umpleby, Margot, Lovegrove, JA, Jackson, KG and Fielding, Barbara (2017) Role of the enterocyte in fructose-induced hypertriglyceridaemia Nutrients, 9 (4), 349.

Shojaee-Moradie, F, Cuthbertson, DJ, Barrett, M, Jackson, NC, Herring, R, Thomas, EL, Bell, J, Kemp, GJ, Wright, J and Umpleby, M (2016) Exercise training reduces liver fat and increases rates of VLDL clearance, but not VLDL production in NAFLD Journal of Clinical Endocrinology and Metabolism.

Dobson, R, Burgess, MI, Sprung, VS, Irwin, A, Hamer, M, Jones, J, Daousi, C, Adams, V, Kemp, GJ, Shojaee-Moradie, F, Umpleby, M and Cuthbertson, DJ (2016) Metabolically healthy and unhealthy obesity: differential effects on myocardial function according to metabolic syndrome, rather than obesity INTERNATIONAL JOURNAL OF OBESITY, 40 (1). pp. 153-161.

Sam, AH, Sleeth, ML, Thomas, EL, Ismail, NA, Daud, NM, Chambers, E, Shojaee-Moradie, F, Umpleby, M, Goldstone, AP, Le Roux, CW, Bech, P, Busbridge, M, Laurie, R, Cuthbertson, DJ, Buckley, A, Ghatei, MA, Bloom, SR, Frost, GS, Bell, JD and Murphy, KG (2015) Circulating Pancreatic Polypeptide Concentrations Predict Visceral and Liver Fat Content JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 100 (3). pp. 1048-1052.

Sibbons, C, Boyle, L, Burdge, GC, Umpleby, M, Lilycrop, KA, Hartwick, CA, Lanham-New, S, Hart, K and Fielding, BA (2015) Evaluation of fatty acid status in children of different nationalities PROCEEDINGS OF THE NUTRITION SOCIETY, 74 (OCE1). E94-E94.

Cuthbertson, DJ, Weickert, MO, Lythgoe, D, Sprung, VS, Dobson, R, Shoajee-Moradie, F, Umpleby, M, Pfeiffer, AFH, Thomas, EL, Bell, JD, Jones, H and Kemp, GJ (2014) External validation of the fatty liver index and lipid accumulation product indices, using H-1-magnetic resonance spectroscopy, to identify hepatic steatosis in healthy controls and obese, insulin-resistant individuals EUROPEAN JOURNAL OF ENDOCRINOLOGY, 171 (5). pp. 561-569.

Birzniece, V, Umpleby, MA, Poljak, A, Handelsman, DJ and Ho, KK (2013) Oral low-dose testosterone administration induces whole-body protein anabolism in postmenopausal women: a novel liver-targeted therapy. Eur J Endocrinol, 169 (3). pp. 321-327.

Bhatia, L, Scorletti, E, Shojaee-Moradie, F, Umpleby, M, Fletcher, A, Bateman, A, Curzen, NP, Clough, GF, Calder, P and Byrne, CD (2013) Peripheral and hepatic insulin resistance are key determinants of progression of non-alcoholic fatty liver disease severity independent of body fat percentage DIABETIC MEDICINE, 30. p. 60.

Elleri, D, Allen, JM, Biagioni, M, Kumareswaran, K, Leelarathna, L, Caldwell, K, Nodale, M, Wilinska, ME, Haidar, A, Calhoun, P, Kollman, C, Umpleby, MA, Acerini, CL, Dunger, DB and Hovorka, R (2012) Efficacy and safety of reduced prandial boluses during closed-loop insulin delivery in adolescents with type 1 diabetes DIABETOLOGIA, 55. S86-S87.

Das, S, Umpleby, M and Shahmanesh, M (2012) Antiretroviral therapy can be associated with increase in LDL apolipoprotein-B residence time without increase in LDL-apo-B oxidation and glycation HIV MEDICINE, 13. p. 50.

Ahmad, A, Isherwood, C, Fielding, BA, Bell, JD, Thomas, EL, Frost, G, Shojaee-Moradie, F, Umpleby, M and Griffin, BA (2012) Individuals with moderately raised liver fat show a greater increase in liver fat in response to a high sugar diet PROCEEDINGS OF THE NUTRITION SOCIETY, 71 (OCE2). E31-E31.

Ahmad, A, Isherwood, C, Bell, JD, Thomas, EL, Frost, G, Umpleby, M and Griffin, BA (2011) Impact of liver fat on the response of plasma triacylglycerol to diets high and low in extrinsic sugars PROCEEDINGS OF THE NUTRITION SOCIETY, 70 (OCE6). E364-E364.

Birzniece, V, Meinhardt, UJ, Umpleby, MA, Handelsman, DJ and Ho, KKY (2011) Interaction between testosterone and growth hormone on whole-body protein anabolism occurs in the liver Journal of Clinical Endocrinology and Metabolism, 96 (4). pp. 1060-1067.

Holt, HB, Wild, SH, Wareham, N, Ekelund, U, Umpleby, M, Shojaee-Moradie, F, Holt, RIG, Phillips, DI and Byrne, CD (2007) Differential effects of fatness, fitness and physical activity energy expenditure on whole-body, liver and fat insulin sensitivity DIABETOLOGIA, 50 (8). pp. 1698-1706.

Holt, HB, Wild, SH, Postle, AD, Zhang, J, Koster, G, Umpleby, M, Shojaee-Moradie, F, Dewbury, K, Wood, PJ, Phillips, DI and Byrne, CD (2007) Cortisol clearance and associations with insulin sensitivity, body fat and fatty liver in middle-aged men DIABETOLOGIA, 50 (5). pp. 1024-1032.

Giannoulis, MG, Sonksen, PH, Umpleby, M, Breen, L, Pentecost, C, Whyte, M, McMillan, CV, Bradley, C and Martin, FC (2006) The effects of growth hormone and/or testosterone in healthy elderly men: a randomized controlled trial The Journal of Clinical Endocrinology & Metabolism, 91 (2). pp. 477-484.

Amin, R, Williams, RM, Frystyk, J, Umpleby, M, Matthews, D, Orskov, H, Dalton, RN and Dunger, DB (2005) Increasing urine albumin excretion is associated with growth hormone hypersecretion and reduced clearance of insulin in adolescents and young adults with type 1 diabetes: The Oxford Regional Prospective Study CLINICAL ENDOCRINOLOGY, 62 (2). pp. 137-144.

Yuen, K, Frystyk, J, Umpleby, M, Fryklund, L and Dunger, D (2004) Changes in free rather than total insulin-like growth factor-I enhance insulin sensitivity and suppress endogenous peak growth hormone (GH) release following short-term low-dose GH administration in young healthy adults JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 89 (8). pp. 3956-3964.

Hordern, VM, Wright, JE, Umpleby, M, Jacobsen, L, Draeger, E and Russell-Jones, DL (2002) Stable isotope studies show differences in effect of insulin detemir and NPH insulin on hepatic glucose output and peripheral glucose uptake after subcutaneous administration in subjects with type1 diabetes DIABETES, 51. A292-A292.

Williams, RM, Amin, R, Shojaee-Moradie, F, Umpleby, M, Ong, KK, Acerini, CL and Dunger, DB (2002) The effects of the specific growth hormone antagonist Pegvisomant on the GH/IGF-I axis and insulin sensitivity in adolescents with TIDM DIABETES, 51. A117-A117.

Wolthers, T, Hoffman, DM, Nugent, AG, Duncan, MW, Umpleby, M and Ho, KKY (2001) Oral estrogen antagonizes the metabolic actions of growth hormone in growth hormone-deficient women AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 281 (6). E1191-E1196.

Shojaee-Moradie, F, Carroll, PV, Chassin, LJ, Gowrie, IJ, Jackson, NC, Jones, RH, Tudor, RS, Umpleby, MA and Hovorka, R (2001) Partitioning glucose Transport/Distribution, disposal. and endogenous production during IVGTT DIABETES, 50. A281-A282.

Hordern, V, Wright, J, Umpleby, M, Jacobsen, L and Russell-Jones, D (2001) Stable isotope studies show effect of insulin detemir and NPH on hepatic glucose output and peripheral glucose uptake after subcutaneous administration in healthy subjects DIABETES, 50. A504-A505.

Carroll, PV, Umpleby, M, Alexander, EL, Egel, VA, Callison, KV, Sonksen, PH and Russell-Jones, DL (1998) Recombinant human insulin-like growth factor-I (rhIGF-I) therapy in adults with type 1 diabetes mellitus: effects on IGFs, IGF-binding proteins, glucose levels and insulin treatment CLINICAL ENDOCRINOLOGY, 49 (6). pp. 739-746.

Joseph, SE, Heaton, N, Potter, D, Pernet, A, Umpleby, M and Amiel, SA (1998) Renal glucose production compensates for the liver during the anhepatic phase of liver transplantation. DIABETOLOGIA, 41. A68-A68.

Carroll, PV, Umpleby, M, Ward, GS, Imuere, S, Alexander, E, Dunger, D, Sonksen, PH and RussellJones, DL (1997) rhIGF-I administration reduces insulin requirements, decreases growth hormone secretion, and improves the lipid profile in adults with IDDM DIABETES, 46 (9). pp. 1453-1458.

Carroll, P, Christ, E, Gowrie, I, Jackson, N, Hovorka, R, Albany, E, Bowes, S, Umpleby, M, Sonksen, P and RussellJones, D (1997) Daily rhIGF-I augments the anabolic effect of insulin in adults with IDDM. DIABETES, 46. p. 945.

Salomon, F, Umpleby, M, Cuneo, RC and Sonksen, PH (1997) Protein, fat and glucose metabolism during treatment with recombinant human growth hormone in adults with growth hormone deficiency. Short-and long-term effects ENDOCRINOLOGY AND METABOLISM, 4 (2). pp. 121-128.

Bowes, SB, Umpleby, M, Cummings, MH, Jackson, NC, Carroll, PV, Lowy, C, Sonksen, PH and RussellJones, DL (1997) The effect of recombinant human growth hormone on glucose and leucine metabolism in Cushing's syndrome JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 82 (1). pp. 243-246.

Bowes, SB, Umpleby, M, Cummings, MH, Jackson, NC, Carroll, PV, Lowy, C, Sönksen, PH and Russell-Jones, DL (1997) The effect of recombinant human growth hormone on glucose and leucine metabolism in Cushing's syndrome. J Clin Endocrinol Metab, 82 (1). pp. 243-246.

RussellJones, DL and Umpleby, M (1996) Protein anabolic action of insulin, growth hormone and insulin-like growth factor I EUROPEAN JOURNAL OF ENDOCRINOLOGY, 135 (6). pp. 631-642.

Watts, GF, Cummings, MH, Umpleby, M, Quiney, JR, Naoumova, R, Thompsom, GR and Sonksen, PH (1995) Simvastatin decreases the hepatic secretion of very-low-density lipoprotein apolipoprotein B-100 in heterozygous familial hypercholesterolaemia: Pathophysiological and therapeutic implications (vol 25, pg 559, 1995) EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 25 (12). p. 980.

Conference or Workshop Item

Umpleby, M, Shojaee-Moradie, F, Fielding, B, Li, X, Isherwood, C, Jackson, N, Wilinska, G, Hovorka, R, Bell, J, Thomas, EL, Wright, J, Frost, GS and Griffin, B (2015) A DIET LOW IN SUGAR REDUCES THE PRODUCTION OF ATHEROGENIC LIPOPROTEINS IN MEN WITH HIGH LIVER FAT In: 83rd Congress of the European-Atherosclerosis-Society (EAS), 2015-03-22 - 2015-03-25, Glasgow, SCOTLAND.

Bhatia, LS, Scorletti, E, Shojaee-Moradie, F, Umpleby, M, Clough, GF, Curzen, NP, Calder, PC and Byrne, CD (2014) High-dose n-3 fatty acid treatment in non-alcoholic fatty liver disease is independently associated with reduced hepatic steatosis and improved hepatic insulin sensitivity

Herring, R, Shojaee-Moradie, F, Umpleby, M, Jackson, N, Jones, R, Derk-Jan, D, Knight, R and Russell-Jones, D (2014) Subcutaneous insulin detemir compared with NPH insulin increases brain potential responses with similar systemic metabolic effects in people with Type 1 diabetes

Hakim, O, Shojaee-Moradie, F, Hart, K, Berry, J, Eastell, R, Gossiel, F, Hannon, R, Umpleby, M, Griffin, B and Lanham-New, S (2011) Evidence of a link between poor bone health, low vitamin D status and CVD risk in caucasian and asian women In: 3rd Joint Meeting of the European-Calcified-Tissue-Society/International-Bone-and-Mineral-Society, 2011-05-07 - 2011-05-11, Athens, GREECE.

Das, S, Shahmansh, M and Umpleby, M (2011) Antiretroviral therapy can be associated with increase in LDL apolipoprotein-B residence time without increase in LDL-apo-B oxidation and glycation

Shojaee-Moradie, F, Backhouse, K, Sarac, I, Stoliniski, M, Robertson, D, Bell, JD, Thomas, EL, Russell-Jones, D and Umpleby, M (2010) Fatty acid oxidation rate is higher in obese women than obese men In: 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD), 2010-09-20 - 2010-09-24, Stockholm, SWEDEN.

Zachariah, S, Sheldon, B, Shojaee-Moradie, E, Jackson, N, Backhouse, K, Johnsen, S, Umpleby, M and Russell-Jones, D (2010) Mechanism for the differential effect of the long-acting insulin analog detemir on weight in patients with type 1 diabetes In: 46th Annual Meeting of the European-Association-for-the- Study-of-Diabetes (EASD), 2010-09-20 - 2010-09-24, Stockholm, SWEDEN.

Li, X, Stolinski, M, Jackson, NC and Umpleby, MA (2010) A NOVEL METHOD FOR THE MEASUREMENT OF PRE beta HDL AND alpha HDL KINETICS WITH STABLE ISOTOPIC LABELLING TECHNIQUES In: 78th Congress of the European-Atherosclerosis-Society, 2010-06-20 - 2010-06-23, Hamburg, GERMANY.

Li, X, Stolinski, M, Jackson, N and Umpleby, M (2009) Pre beta and alpha HDL kinetics measured by a stable isotopic and two step electrophoresis technique In: 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, 2009-09-30 - 2009-10-02, Vienna, AUSTRIA.

Potocka, E, Hovorka, R, Baughman, R, Umpleby, M, Diaz, M, Chen, R, Cassidy, J, Boss, A and Richardson, P (2009) Technosphere insulin suppresses endogenous glucose production earlier than a rapid-acting analogue (lispro) and an inhaled insulin (Exubera (R)) In: 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, 2009-09-30 - 2009-10-02, Vienna, AUSTRIA.

Sarac, I, Backhouse, K, Shojaee-Moradie, F, Robertson, D, Stolinski, M and Umpleby, M (2009) The effect of rimonabant on resting energy expenditure, insulin sensitivity, plasma lipids and adipokines concentrations In: Meeting of the British-Pharmacological-Society, Clinical Pharmacology Section, 2008-12-16 - 2008-12-18, Brighton, ENGLAND.

Potocka, E, Hovorka, R, Baughman, RA, Umpleby, M, Diaz, MLM, Chen, R, Boss, AH and Richardson, PC (2009) AFRESA (TM) Suppresses Endogenous Glucose Production Earlier Than a Rapid-Acting Analog (Lispro) and Inhaled Exubera (R) In: 69th Annual Meeting of the American-Diabetes-Association, 2009-06-05 - 2009-06-09, New Orleans, LA.

Shahmanesh, M, Das, S and Umpleby, M (2009) Pre-treatment alterations in lipoprotein metabolism predict changes in blood lipids after antiretroviral therapy In: 11th International Workshop on AdverseDrug Reactions and Co-Morbidities in HIV, 2009-10-26 - 2009-10-28, Philadelphia, PA.

Li, X, Stolinski, M, Shojaee-Moradie, F, Jackson, N and Umpleby, M (2008) DEVELOPMENT OF A METHOD TO MEASURE HIGH DENSITY LIPOPROTEIN KINETICS USING STABLE ISOTOPES

Byrne, CDT, Holt, HB, Wild, SH, Wareham, N, Ekelund, U, Umpleby, M, Shojaee-Moradie, E, Holt, RIG and Phillips, DI (2007) Differential impact of fatness, fitness and physical activity energy expenditure on whole body, liver and fat insulin sensitivity In: 43rd Annual Meeting of the European-Association-for-the-Study-of-Diabetes, 2007-09-18 - 2007-09-21, Amsterdam, NETHERLANDS.

Stolinski, M, Li, X, Lo, A, Shojaee-Moradie, F, Alam, S, Wheeler, B, Pentecost, C, Jackson, N, Jefferson, W and Umpleby, M (2006) A supervised exercise programme increases HDL ApoA-1 production rate in type 2 diabetes In: 42nd Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), 2006-09-14 - 2006-09-17, Copenhagen, DENMARK.

Sharma, R, Tigas, S, Rauchhaus, M, Poole-Wilson, PP, Coats, AJ, Umpleby, M, Carroll, PV and Anker, SD (2005) Substrate metabolism in patients with chronic heart failure with and without cachexia In: 78th Annual Scientific Session of the American-Heart-Association, 2005-11-13 - 2005-11-16, Dallas, TX.

Shahmanesh, M, Das, S, Shojaee-Moradie, F, Stolinski, M, Jefferson, W, Jackson, N, Gilleran, G, Crabtree, NJ, Nightingale, P, Cramb, R and Umpleby, M (2004) The reduction in serum adiponectin levels in HIV patients correlates with apolipoprotein-B clearance In: 6th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 2004-10-25 - 2004-10-28, Washington, DC.

Umpleby, M, Shojaee-Moradie, F, Das, S, Stolinski, M, Jefferson, W, Jackson, N, Cramb, R and Shahmanesh, M (2004) Adiponectin levels are reduced in HIV infection and after treatment and correlate with VLDL and IDL apolipoprotein B fractional catabolic rate In: 40th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, 2004-09-05 - 2004-09-09, Munich, GERMANY.

Whyte, M, Jackson, N, Shojaee-moradie, F, Beale, R, Treacher, D, Carroll, P, Jones, RH and Umpleby, M (2004) The effect of insulin therapy on glucose production rate, glucose uptake, lipolysis and proteolysis in non-surgical ICU patients In: 40th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, 2004-09-05 - 2004-09-09, Munich, Germany.

Das, S, Stolinski, M, Jefferson, W, Jackson, N, Gilleran, G, O'Connor, M, Cramb, R, Umpleby, M and Shahmanesh, M (2003) Effects of HIV infection, antiviral treatment and body fat changes on V-LDL-apolipoprotein-B metabolism In: 5th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 2003-07-08 - 2003-07-11, Paris, FRANCE.

Das, S, Stolinski, M, Jefferson, W, Jackson, N, Gilleran, G, O'Connor, M, Cramb, R, Shahmanesh, M and Umpleby, M (2003) The relationship between fat distribution and VLDL and IDL metabolism in HIV-infected adults In: 5th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, 2003-07-08 - 2003-07-11, Paris, FRANCE.

Williams, R, Amin, R, Shojaee-Moradie, F, Umpleby, M, Acerini, C and Dunger, D (2003) Effects of the specific growth hormone receptor antagonist Pegvisomant on insulin sensitivity & lipid metabolism in adolescents with T1DM In: 63rd Scientific Sessions of the American-Diabetes-Association, 2003-06-13 - 2003-06-17, NEW ORLEANS, LOUISIANA.

Hordern, V, Wright, J, Umpleby, M, Jacobsen, L and Russell-Jones, D (2003) Stable isotope studies show differences in effect of lnsulin detemir and NPH on hepatic glucose output after subcutaneous administration in subjects with type 2 diabetes mellitus In: 63rd Scientific Sessions of the American-Diabetes-Association, 2003-06-13 - 2003-06-17, NEW ORLEANS, LOUISIANA.

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