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Items where Author is "Stewart, G"

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Article

Butler, Rachel E., Smith, Alex A., Mendum, Tom A., Chandran, Aneesh, Wu, Huihai, Lefrançois, Louise, Chambers, Mark, Soldati, Thierry and Stewart, Graham R. (2020) Mycobacterium bovis uses the ESX-1 Type VII secretion system to escape predation by the soil-dwelling amoeba Dictyostelium discoideum The ISME Journal.

Mendum, Tom A., Chandran, Aneesh, Williams, Kerstin, Vordermeier, H. Martin, Villarreal-Ramos, Bernardo, Wu, H., Singh, Albel, Smith, Alex A., Butler, Rachel E., Prasad, Aravind, Bharti, Neeraj, Banerjee, Ruma, Kasibhatla, Sunitha M., Bhatt, Apoorva, Stewart, Graham R. and McFadden, Johnjoe (2019) Transposon libraries identify novel Mycobacterium bovis BCG genes involved in the dynamic interactions required for BCG to persist during in vivo passage in cattle BMC Genomics, 20, 431. pp. 1-13.

Taylor, G. Michael, Murphy, Eileen M., Mendum, Thomas, Pike, Alistair W.G, Linscott, Bethan, Wu, Huihai, O'Grady, Justin, Richardson, Hollian, O'Donovan, Edmond, Troy, Carmelita and Stewart, Graham (2018) Leprosy at the edge of Europe—Biomolecular, isotopic and osteoarchaeological findings from medieval Ireland PLOS One.

Mendum, Thomas, Taylor, G Michael, Donoghue, Helen D, Wu, Huihai, Szalontai, Csaba, Marcsik, Antónia, Molnár, Erika, Pálfi, György and Stewart, Graham (2018) The Genome Sequence of a SNP Type 3K strain of Mycobacterium leprae isolated from a 7th Century Hungarian case of Lepromatous Leprosy. International Journal of Osteoarchaeology, 28 (4). pp. 439-447.

Schuenemann, Verena J, Avanzi, Charlotte, Krause-Kyora, Ben, Seitz, Alexander, Herbig, Alexander, Inskip, Sarah, Bonazzi, Marion, Reiter, Ella, Urban, Christian, Pedersen, Dorthe Dangvard, Taylor, G Michael, Singh, Pushpendra, Stewart, Graham, Veleminsky, Petr, Likovsky, Jakub, Marcsik, Antonia, Molnar, Erika, Palfi, Gyorgy, Mariotti, Valentina, Riga, Alessandro, Belcastro, M Giovanna, Boldsen, Jesper L, Nebel, Almut, Mays, Simon, Donoghue, Helen D, Zakrzewski, Sonia, Benjak, Andrej, Nieselt, Kay, Cole, Stewart T and Krause, Johannes (2018) Ancient Mycobacterium leprae genomes reveal a high diversity of Mycobacterium leprae in medieval Europe PLOS Pathogens, 14 (5), e1006997.

Bucca, Giselda, Pothi, Radhika, Hesketh, Andrew, Moller-Levet, Carla, Hodgson, David A, Laing, Emma, Stewart, Graham and Smith, Colin (2018) Translational control plays an important role in the adaptive heat-shock response of Streptomyces coelicolor. Nucleic Acids Research, 46 (11). pp. 5692-5703.

Butler, Rachel, Krishnan, N, Garcia-Jimenez, W, Francis, R, Martyn, A, Mendum, T, Felemban, Shaza, Locker, Nicolas, Salguero Bodes, J, Robertson, B and Stewart, Graham (2017) Susceptibility of M. tuberculosis-infected host cells to phospho-MLKL driven necroptosis is dependent on cell type and presence of TNFα Virulence, 8 (8). pp. 1820-1832.

Riitho, Victor, Walters, Adam A., Somavarapu, Satyanarayana, Lamp, Benjamin, Rümenapf, Till, Krey, Thomas, Rey, Felix A., Oviedo-Orta, Ernesto, Stewart, Graham R., Locker, Nicolas, Steinbach, Falko and Graham, Simon (2017) Design and evaluation of the immunogenicity and efficacy of a biomimetic particulate formulation of viral antigens Scientific Reports, 7, 13743.

Donoghue, H, Taylor, G, Stewart, Graham, Lee, O, Wu, H, Besra, G and Minnikin, D (2017) Positive Diagnosis of Ancient Leprosy and Tuberculosis Using Ancient DNA and Lipid Biomarkers Diversity, 9 (4), 46.

Inskip, S, Taylor, G, Anderson, S and Stewart, Graham (2017) Leprosy in pre-Norman Suffolk, UK: biomolecular and geochemical analysis of the woman from Hoxne Journal of Medical Microbiology, 66. pp. 1640-1649.

Mokhtar, H, Biffar, L, Somavarapu, S, Frossard, J-P, Mcgowan, Sarah, Pedrera, M, Strong, R, Edwards, JC, Garcia-Durán, M, Rodriguez, MJ, Stewart, Graham, Steinbach, Falko and Graham, Simon (2017) Evaluation of hydrophobic chitosan-based particulate formulations of porcine reproductive and respiratory syndrome virus vaccine candidate T cell antigens Veterinary Microbiology, 209. pp. 66-74.

Wu, Huihai, von Kamp, A, Leoncikas, Vytautas, Mori, W, Sahin, N, Gevorgyan, A, Linley, C, Grabowski, M, Mannan, AA, Stoy, Nicholas, Stewart, Graham, Ward, LT, Lewis, David, Sroka, J, Matsuno, H, Klamt, S, Westerhoff, HV, McFadden, Johnjoe, Plant, NJ and Kierzek, Andrzej (2016) MUFINS: Multi-Formalism Interaction Network Simulator NPJ Systems Biology and Applications, 2, 16032.

Walters, AA, Somavarapu, S, Riitho, V, Stewart, GR, Charleston, B, Steinbach, F and Graham, SP (2015) Assessment of the enhancement of PLGA nanoparticle uptake by dendritic cells through the addition of natural receptor ligands and monoclonal antibody VACCINE, 33 (48). pp. 6588-6595.

Hollingworth, R, Skalka, GL, Stewart, GS, Hislop, AD, Blackbourn, DJ and Grand, RJ (2015) Activation of DNA Damage Response Pathways during Lytic Replication of KSHV VIRUSES-BASEL, 7 (6). pp. 2908-2927.

Inskip, SA, Taylor, GM, Zakrzewski, SR, Mays, SA, Pike, AWG, Llewellyn, G, Williams, CM, Lee, OY-C, Wu, HHT, Minnikin, DE, Besra, GS and Stewart, GR (2015) Osteological, Biomolecular and Geochemical Examination of an Early Anglo-Saxon Case of Lepromatous Leprosy PLOS ONE, 10 (5), ARTN e.

Mendum, TA, Wu, H, Kierzek, AM and Stewart, GR (2015) Lipid metabolism and Type VII secretion systems dominate the genome scale virulence profile of Mycobacterium tuberculosis in human dendritic cells BMC Genomics, 16, ARTN 3.

Francis, RJ, Butler, RE and Stewart, GR (2014) Mycobacterium tuberculosis ESAT-6 is a leukocidin causing Ca2+ influx, necrosis and neutrophil extracellular trap formation CELL DEATH & DISEASE, 5.

Mendum, TA, Schuenemann, VJ, Roffey, S, Taylor, GM, Wu, H, Singh, P, Tucker, K, Hinds, J, Cole, ST, Kierzek, AM, Nieselt, K, Krause, J and Stewart, GR (2014) Mycobacterium leprae genomes from a British medieval leprosy hospital: Towards understanding an ancient epidemic BMC Genomics, 15 (1).

Mendum, TA, Schuenemann, VJ, Roffey, S, Taylor, GM, Wu, H, Singh, P, Tucker, K, Hinds, J, Cole, ST, Kierzek, AM, Nieselt, K, Krause, J and Stewart, GR (2014) Mycobacterium leprae genomes from a British medieval leprosy hospital: towards understanding an ancient epidemic BMC GENOMICS, 15, ARTN 2.

Taylor, GM, Tucker, K, Butler, R, Pike, AW, Lewis, J, Roffey, S, Marter, P, Lee, OY, Wu, HH, Minnikin, DE, Besra, GS, Singh, P, Cole, ST and Stewart, GR (2013) Detection and strain typing of ancient Mycobacterium leprae from a medieval leprosy hospital. PLoS One, 8 (4).

Schuenemann, VJ, Bos, KI, Krause, J, Singh, P, Benjak, A, Busso, P, Cole, ST, Mendum, TA, Wu, H, Stewart, GR, Taylor, GM, Krause-Kyora, B, Nebel, A, Jäger, G, Herbig, A, Nieselt, K, Economou, C, Boldsen, JL, Kjellström, A, Bauer, P, Lee, OY-C, Wu, HHT, Minnikin, DE, Besra, GS, Tucker, K, Roffey, S and Sow, SO (2013) Genome-wide comparison of medieval and modern Mycobacterium leprae Science, 341 (6142). pp. 179-183.

Snelgrove, RJ, Cornere, MM, Edwards, L, Dagg, B, Keeble, J, Rodgers, A, Lyonga, DE, Stewart, GR, Young, DB, Walker, B and Hussell, T (2012) OX40 ligand fusion protein delivered simultaneously with the BCG vaccine provides superior protection against murine Mycobacterium tuberculosis infection. Journal of Infectious Diseases, 205 (6). pp. 975-983.

Butler, RE, Brodin, P, Jang, J, Jang, MS, Robertson, BD, Gicquel, B and Stewart, GR (2012) The balance of apoptotic and necrotic cell death in Mycobacterium tuberculosis infected macrophages is not dependent on bacterial virulence. PLoS One, 7 (10).

Estorninho, M, Smith, H, Thole, J, Harders-Westerveen, J, Kierzek, A, Butler, RE, Neyrolles, O and Stewart, GR (2010) ClgR regulation of chaperone and protease systems is essential for Mycobacterium tuberculosis parasitism of the macrophage Microbiology, 156 (11). pp. 3445-3455.

Brodin, P, Poquet, Y, Levillain, F, Peguillet, I, Larrouy-Maumus, G, Gilleron, M, Ewann, F, Christophe, T, Fenistein, D, Jang, J, Jang, M-S, Park, S-J, Rauzier, J, Carralot, J-P, Shrimpton, R, Genovesio, A, Gonzalo-Asensio, JA, Puzo, G, Martin, C, Brosch, R, Stewart, GR, Gicquel, B and Neyrolles, O (2010) High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling PLOS PATHOGENS, 6 (9), ARTN e.

Butler, RE, Cihlarova, V and Stewart, GR (2010) Effective generation of reactive oxygen species in the mycobacterial phagosome requires K plus efflux from the bacterium CELLULAR MICROBIOLOGY, 12 (8). pp. 1186-1193.

Wilkinson, KA, Newton, SM, Stewart, GR, Martineau, AR, Patel, J, Sullivan, SM, Herrmann, J-L, Neyrolles, O, Young, DB and Wilkinson, RJ (2009) Genetic determination of the effect of post-translational modification on the innate immune response to the 19 kDa lipoprotein of Mycobacterium tuberculosis BMC MICROBIOLOGY, 9, ARTN 9.

Beste, DJ, Espasa, M, Bonde, B, Kierzek, AM, Stewart, GR and McFadden, J (2009) The genetic requirements for fast and slow growth in mycobacteria. PLoS One, 4 (4), e5349. - - -.

Beste, DJ, Espasa, M, Bonde, B, Kierzek, AM, Stewart, GR and McFadden, J (2009) The genetic requirements for fast and slow growth in mycobacteria. PLoS One, 4 (4), e5349. - - -.

Elkadri, RAS, Grobler, A-K, Bermudez-Fajardo, A, Puolakkainen, M, Stewart, G and Oviedo-Orta, E (2009) Effects of recombinant vectors expressing Chlamydia pneumoniae's major outer membrane protein (MOMP) on humoral and T cell-mediated immunity. JOURNAL OF IMMUNOLOGY, 182.

Henao-Tamayo, M, Junqueira-Kipnis, AP, Ordway, D, Gonzales-Juaffero, M, Stewart, GR, Young, DB, Wilkinson, RJ, Basaraba, RJ and Orme, IM (2007) A mutant of Mycobacterium tuberculosis lacking the 19-kDa lipoprotein Rv3763 is highly attenuated in vivo but retains potent vaccinogenic properties VACCINE, 25 (41). pp. 7153-7159.

Beste, DJV, Hooper, T, Stewart, G, Bonde, B, Avignone-Rossa, C, Bushell, M, Wheeler, P, Klamt, S, Kierzek, AM and McFadden, J (2007) GSMN-TB: a web-based genome scale network model of Mycobacterium tuberculosis metabolism GENOME BIOLOGY, 8 (5), ARTN r.

Newton, SM, Smith, RJ, Wilkinson, KA, Nicol, MP, Garton, NJ, Staples, KJ, Stewart, GR, Wain, JR, Martineau, AR, Fandrich, S, Smallie, T, Foxwell, B, Al-Obaidi, A, Shafi, J, Rajakumar, K, Kampmann, B, Andrew, PW, Ziegler-Heitbrock, L, Barer, MR and Wilkinson, RJ (2006) A deletion defining a common Asian lineage of Mycobacterium tuberculosis associates with immune subversion PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103 (42). pp. 15594-15598.

Humphreys, IR, Stewart, GR, Turner, DJ, Patel, J, Karamanou, D, Snelgrove, RJ and Young, DB (2006) A role for dendritic cells in the dissemination of mycobacterial infection MICROBES AND INFECTION, 8 (5). pp. 1339-1346.

Pitarque, S, Herrmann, JL, Duteyrat, JL, Jackson, M, Stewart, GR, Lecointe, F, Payre, B, Schwartz, O, Young, DB, Marchal, G, Lagrange, PH, Puzo, G, Gicquel, B, Nigou, J and Neyrolles, O (2005) Deciphering the molecular bases of Mycobacterium tuberculosis binding to the lectin DC-SIGN reveals an underestimated complexity BIOCHEMICAL JOURNAL, 392. pp. 615-624.

Stewart, GR, Patel, J, Robertson, BD, Rae, A and Young, DB (2005) Mycobacterial mutants with defective control of phagosomal acidification PLOS PATHOGENS, 1 (3), ARTN e. pp. 269-278.

Stewart, GR, Wilkinson, KA, Newton, SA, Sullivan, SA, Neyrolles, O, Wain, JR, Patel, J, Pool, KL, Young, DB and Wilkinson, RJ (2005) Effect of deletion or overexpression of the 19-kilodalton lipoprotein Rv3763 on the innate response to Mycobacterium tuberculosis INFECTION AND IMMUNITY, 73 (10). pp. 6831-6837.

Murphy, HN, Stewart, GR, Mischenko, VV, Apt, AS, Harris, R, McAlister, MSB, Driscoll, PC, Young, DB and Robertson, BD (2005) The OtsAB pathway is essential for trehalose biosynthesis in Mycobacterium tuberculosis JOURNAL OF BIOLOGICAL CHEMISTRY, 280 (15). pp. 14524-14529.

Wilkinson, KA, Stewart, GR, Newton, SM, Vordermeier, HM, Wain, JR, Murphy, HN, Horner, K, Young, DB and Wilkinson, RJ (2005) Infection biology of a novel alpha-crystallin of Mycobacterium tuberculosis: Acr2 JOURNAL OF IMMUNOLOGY, 174 (7). pp. 4237-4243.

Stewart, GR, Newton, SM, Wilkinson, KA, Humphreys, IR, Murphy, HN, Robertson, BD, Wilkinson, RJ and Young, DB (2005) The stress-responsive chaperone alpha-crystallin 2 is required for pathogenesis of Mycobacterium tuberculosis MOLECULAR MICROBIOLOGY, 55 (4). pp. 1127-1137.

Blokpoel, MCJ, Murphy, HN, O'Toole, R, Wiles, S, Runn, ESC, Stewart, GR, Young, DB and Robertson, BD (2005) Tetracycline-inducible gene regulation in mycobacteria NUCLEIC ACIDS RESEARCH, 33 (2), ARTN e22.

Stewart, GR and Young, DB (2004) Heat-shock proteins and the host-pathogen interaction during bacterial infection CURRENT OPINION IN IMMUNOLOGY, 16 (4). pp. 506-510.

Stewart, GR, Robertson, BD and Young, DB (2004) Analysis of the function of mycobacterial DnaJ proteins by overexpression and microarray profiling TUBERCULOSIS, 84 (3-4). pp. 180-187.

Papatheodorou, I, Sergot, M, Randall, M, Stewart, GR and Robertson, BD (2004) Visualization of microarray results to assist interpretation TUBERCULOSIS, 84 (3-4). pp. 275-281.

Taylor, GM, Stewart, GR, Cooke, M, Chaplin, S, Ladva, S, Kirkup, J, Palmer, S and Young, DB (2003) Koch's Bacillus - a look at the first isolate of Mycobacterium tuberculosis from a modern perspective MICROBIOLOGY-SGM, 149. pp. 3213-3220.

Stewart, GR, Robertson, BD and Young, DB (2003) Tuberculosis: A problem with persistence NATURE REVIEWS MICROBIOLOGY, 1 (2). pp. 97-105.

Stewart, GR, Wernisch, L, Stabler, R, Mangan, JA, Hinds, J, Laing, KG, Young, DB and Butcher, PD (2002) Dissection of the heat-shock response in Myobacterium tuberculosis using mutants and microarrays MICROBIOLOGY-SGM, 148. pp. 3129-3138.

Stewart, GR, Wermisch, L, Stabler, R, Mangan, JA, Hinds, J, Laing, KG, Butcher, PD and Young, DB (2002) The heat shock response of Mycobacterium tuberculosis: linking gene expression, immunology and pathogenesis COMPARATIVE AND FUNCTIONAL GENOMICS, 3 (4). pp. 348-351.

Bhatt, A, Stewart, GR and Kieser, T (2002) Transposition of Tn4560 of Streptomyces fradiae in Mycobacterium smegmatis FEMS MICROBIOLOGY LETTERS, 206 (2). pp. 241-246.

Young, DB and Stewart, GR (2002) Tuberculosis vaccines BRITISH MEDICAL BULLETIN, 62. pp. 73-86.

Stewart, GR, Snewin, VA, Walzl, G, Hussell, T, Tormay, P, O'Gaora, P, Goyal, M, Betts, J, Brown, IN and Young, DB (2001) Overexpression of heat-shock proteins reduces survival of Mycobacterium tuberculosis in the chronic phase of infection. Nat Med, 7 (6). pp. 732-737.

Stewart, GR, Perry, RN and Wright, DJ (2001) Occurrence of dopamine in Panagrellus redivivus and Meloidogyne incognita NEMATOLOGY, 3. pp. 843-848.

Dussurget, O, Stewart, G, Neyrolles, O, Pescher, P, Young, D and Marchal, G (2001) Role of Mycobacterium tuberculosis copper-zinc superoxide dismutase INFECTION AND IMMUNITY, 69 (1). pp. 529-533.

Yeremeev, VV, Stewart, GR, Neyrolles, O, Skrabal, K, Avdienko, VG, Apt, AS and Young, DB (2000) Deletion of the 19kDa antigen does not alter the protective efficacy of BCG TUBERCLE AND LUNG DISEASE, 80 (6). pp. 243-247.

Stewart, GR, Ehrt, S, Riley, LW, Dale, JW and McFadden, J (2000) Deletion of the putative antioxidant noxR1 does not alter the virulence of Mycobacterium tuberculosis H37Rv TUBERCLE AND LUNG DISEASE, 80 (4-5). pp. 237-242.

Stewart, GR, Boussinesq, M, Coulson, T, Elson, L, Nutman, T and Bradley, JE (1999) Onchocerciasis modulates the immune response to mycobacterial antigens CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 117 (3). pp. 517-523.

Bradley, JE, Atogho, BM, Elson, L, Stewart, GR and Boussinesq, M (1998) A cocktail of recombinant Onchocerca volvulus antigens for serologic diagnosis with the potential to predict the endemicity of onchocerciasis infection AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 59 (6). pp. 877-882.

Stewart, GR, Zhu, YH, Parredes, W, Tree, TIM, Guderian, R and Bradley, JE (1997) Novel cuticular collagen Ovcol-1 of Onchocerca volvulus is preferentially recognized by immunoglobulin G3 from putatively immune individuals INFECTION AND IMMUNITY, 65 (1). pp. 164-170.

Conference or Workshop Item

Fisher, RA, Rowan, A, Stares, M, Webster-Smith, MF, Lewis, R, Kilbum, LS, Nicol, D, Stewart, G, Michael, A, Vasudev, N, Hazen, S, Turalijic, S, Pickering, LM, Gore, ME, Snowdon, C, Bliss, JM, Swanton, C and Larkin, JMG (2014) A-PREDICT: A phase II study of axitinib in patients with metastatic renal cell cancer unsuitable for nephrectomy (CRUKE/11/061) In: 50th Annual Meeting of the American-Society-of-Clinical-Oncology, 2014-05-30 - 2014-06-03, Chicago, IL.

Minnikin, DE, Taylor, GM, Stewart, GR, Mendum, TA, Roffey, S, Tucker, K, Lee, OY-C, Wu, HHT, Besra, GS and Cole, ST (2014) Defining the origins and spread of leprosy using molecular biomarkers In: 83rd Annual Meeting of the American-Association-of-Physical-Anthropologists, 2014-04-08 - 2014-04-12, Calgary, CANADA.

El-Kadri, R, Bermudez-Fajardo, A, Stewart, G, Puolakkainen, M and Oviedo-Orta, E (2010) Anti-inflammatory and atheroprotectiveeffects of Chlamyiphia pneumoniaerecombinant MOMP In: Annual Congress of the British-Society-for-Immunology, 2010-12-06 - 2010-12-10, Liverpool, ENGLAND.

El Kadri, R, Bermudez-Fajardo, A, Puolakkainen, M, Stewart, G and Oviedo-Orta, E (2010) Anti-inflammatory and atheroprotective effects of Chlamydia pneumoniae recombinant MOMP

El Kadri, R, Bermudez-Fajardo, A, Puolakkainen, M, Stewart, G and Oviedo-Orta, E (2010) Effect of immunisation with C. pneumoniae rMOMP on atherosclerosis development

Stark, A, Bermudez-Fajardo, A, El Kadri, R, Stewart, G and Oviedo-Orta, E (2010) Study of the immunomodulatory properties of the major outer membrane protein (MOMP) of Chlamydophila pneumoniae in the context of atherosclerosis

Ciaramella, A, Cavone, A, Santucci, MB, Garg, SK, Sanarico, N, Bocchino, M, Galati, D, Martino, A, Auricchio, G, D'Orazio, M, Stewart, GR, Neyrolles, O, Young, DB, Colizzi, V and Fraziano, M (2004) Induction of apoptosis and release of interleukin-1 beta by cell wall-associated 19-kDa lipoprotein during the course of mycobacterial infection In: European Congress for Immunology, 2004-06-08 - 2004-06-12, Rhodes, GREECE.

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