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Items where Author is "Nicklin, S"

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Article

Ma, J, Duffy, MR, Deng, L, Dakin, RS, Uil, T, Custers, J, Kelly, SM, McVey, JH, Nicklin, SA and Baker, AH (2015) Manipulating Adenovirus Hexon Hypervariable Loops Dictates Immune Neutralisation and Coagulation Factor X-dependent Cell Interaction In Vitro and In Vivo PLOS PATHOGENS, 11 (2), ARTN e.

Alba, R, Bradshaw, AC, Coughlan, L, Denby, L, McDonald, RA, Waddington, SN, Buckley, SM, Greig, JA, Parker, AL, Miller, AM, Wang, H, Lieber, A, van Rooijen, N, McVey, JH, Nicklin, SA and Baker, AH (2010) Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors. Blood, 116 (15). pp. 2656-2664.

Greig, JA, Buckley, SMK, Waddington, SN, Parker, AL, Bhella, D, Pink, R, Rahim, AA, Morita, T, Nicklin, SA, McVey, JH and Baker, AH (2009) Erratum: "Influence of coagulation factor X on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors" (Molecular Theraphy (2009) 10.1038/mt.2009.152) Molecular Therapy, 17 (10).

Greig, JA, Buckley, SMK, Waddington, SN, Parker, AL, Bhella, D, Pink, R, Rahim, AA, Morita, T, Nicklin, SA, McVey, JH and Baker, AH (2009) Influence of Coagulation Factor X on In Vitro and In Vivo Gene Delivery by Adenovirus (Ad) 5, Ad35, and Chimeric Ad5/Ad35 Vectors MOLECULAR THERAPY, 17 (10). pp. 1683-1691.

Alba, R, Bradshaw, AC, Parker, AL, Bhella, D, Waddington, SN, Nicklin, SA, van Rooijen, N, Custers, J, Goudsmit, J, Barouch, DH, Mcvey, JH and Baker, AH (2009) Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer BLOOD, 114 (5). pp. 965-971.

Lenaerts, L, McVey, JH, Baker, AH, Denby, L, Nicklin, S, Verbeken, E and Naesens, L (2009) Mouse adenovirus type 1 and human adenovirus type 5 differ in endothelial cell tropism and liver targeting. J Gene Med, 11 (2). pp. 119-127.

Parker, AL, Waddington, SN, Buckley, SM, Custers, J, Havenga, MJ, van Rooijen, N, Goudsmit, J, McVey, JH, Nicklin, SA and Baker, AH (2009) Effect of neutralizing sera on factor x-mediated adenovirus serotype 5 gene transfer. J Virol, 83 (1). pp. 479-483.

White, K, Buening, H, Kritz, A, Janicki, H, McVey, J, Perabo, L, Murphy, G, Odenthal, M, Work, LM, Hallek, M, Nicklin, SA and Baker, AH (2008) Engineering adeno-associated virus 2 vectors for targeted gene delivery to atherosclerotic lesions GENE THERAPY, 15 (6). pp. 443-451.

Waddington, SN, McVey, JH, Bhella, D, Parker, AL, Barker, K, Atoda, H, Pink, R, Buckley, SMK, Greig, JA, Denby, L, Custers, J, Morita, T, Francischetti, IMB, Monteiro, RQ, Barouch, DH, van Rooijen, N, Napoli, C, Hlavenga, MJE, Nicklin, SA and Baker, AH (2008) Adenovirus serotype 5 hexon mediates liver gene transfer CELL, 132 (3). pp. 397-409.

Denby, L, Work, LM, Von Seggern, DJ, Wu, E, Mcvey, JH, Nicklin, SA and Baker, AH (2007) Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p MOLECULAR THERAPY, 15 (9). pp. 1647-1654.

Waddington, SN, Parker, AL, Havenga, M, Nicklin, SA, Buckley, SMK, Mcvey, JH and Baker, AH (2007) Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: Fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5 JOURNAL OF VIROLOGY, 81 (17). pp. 9568-9571.

Kritz, AB, Nicol, CG, Dishart, KL, Nelson, R, Holbeck, S, Von Seggern, DJ, Work, LM, McVey, JH, Nicklin, SA and Baker, AH (2007) Adenovirus 5 fibers mutated at the putative HSPG-binding site show restricted retargeting with targeting peptides in the HI loop MOLECULAR THERAPY, 15 (4). pp. 741-749.

Parker, AL, McVey, JH, Doctor, JH, Lopez-Franco, O, Waddington, SN, Havenga, MJE, Nicklin, SA and Baker, AH (2007) Influence of coagulation factor zymogens on the infectivity of adenoviruses pseudotyped with fibers from subgroup D JOURNAL OF VIROLOGY, 81 (7). pp. 3627-3631.

Kritz, AB, Nicol, CG, Dishart, KL, Nelson, R, Holbeck, S, Von Seggern, DJ, Work, LM, McVey, JH, Nicklin, SA and Baker, AH (2007) Adenovirus 5 fibers mutated at the putative HSPG-binding site show restricted retargeting with targeting peptides in the HI loop. Mol Ther, 15 (4). pp. 741-749.

Parker, AL, Waddington, SN, Nicol, CG, Shayakhmetov, DM, Buckley, SM, Denby, L, Kemball-Cook, G, Ni, S, Lieber, A, McVey, JH, Nicklin, SA and Baker, AH (2006) Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes BLOOD, 108 (8). pp. 2554-2561.

Parker, AL, Nicol, CG, Waddington, SN, Buckley, SM, Shayakhmetov, DM, Ni, SH, Lieber, A, McVey, JH, Denby, L, Nicklin, SA and Baker, AH (2006) Hepatic Tropism of Adenoviral Type 5 Vectors Can Be Mediated by Multiple Coagulation Factors MOLECULAR THERAPY, 13. S143-S143.

Conference or Workshop Item

Greig, JA, Buckley, SMK, Waddington, SN, Parker, AL, Bhella, D, Pink, R, Morita, T, Custers, J, Goudsmit, J, Nicklin, SA, McVey, JH and Baker, AH (2009) Influence of Factor X on In Vitro and In Vivo Gene Delivery by Ad5 and Ad35 Vectors In: 12th Annual Meeting of the American Society of Gene Therapy, 2009-05-27 - 2009-05-30, San Diego, CA.

Greig, JA, McVey, JH, Waddington, SN, Parker, AL, Buckley, SMK, Havenga, MJE, Nicklin, SA and Baker, AH (2008) Factor X enhances binding and transduction of human cancer cell lines by adenovirus (Ad) serotype 5 vectors but not by Ad35 In: 5th Annual Conference of the British-Society-for-Gene-Therapy, 2008-04-07 - 2008-04-09, Edinburgh, SCOTLAND.

Waddington, SN, Mcvey, JH, Bhella, D, Parker, AL, Barker, K, Atoda, K, Pink, R, Buckley, SMK, Greig, JA, Denby, L, Custers, J, Morita, T, Francischetti, IMB, Monteiro, RQ, Barouch, DH, van Rooijen, N, Napoli, C, Havenga, M, Nicklin, SA and Baker, AH (2008) A critical role for the adenovirus serotype 5 hexon in liver gene transfer In: 5th Annual Conference of the British-Society-for-Gene-Therapy, 2008-04-07 - 2008-04-09, Edinburgh, SCOTLAND.

Parker, AL, McVey, JH, Waddington, SN, Buckley, SMK, Francischetti, IMB, Monteiro, RQ, Nicklin, SA and Baker, AH (2008) An exosite within the human FX serine protease domain mediates cell transduction of AD5: FX complexes In: 5th Annual Conference of the British-Society-for-Gene-Therapy, 2008-04-07 - 2008-04-09, Edinburgh, SCOTLAND.

White, K, Buening, H, McVey, J, Murphy, G, Work, L, Hallek, M, Nicklin, S and Baker, A (2007) Development and characterisation of viral vectors targeted to atherosclerotic plaques In: Annual Scientific Conference of the British-Cardiovascular-Society, 2007-06-04 - 2007-06-07, Glasgow, SCOTLAND.

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