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Clark, C, Smuk, M, Cummins, S, Eldridge, S, Fahy, A, Lewis, David, Moore, Derek, Smith, N, Taylor, SJC and Stansfeld, SA (2017) An Olympic Legacy? Does the urban regeneration associated with the London 2012 Olympic Games impact on adolescent mental health? American Journal of Epidemiology.

Davies, GF, Greenhough, BJ, Hobson-West, P, Kirk, RGW, Applebee, K, Bellingan, LC, Berdoy, M, Buller, H, Cassaday, HJ, Davies, K, Diefenbacher, D, Druglitro, T, Escobar, MP, Friese, C, Herrmann, K, Hinterberger, A, Jarrett, WJ, Jayne, K, Johnson, AM, Johnson, ER, Konold, T, Leach, MC, Leonelli, S, Lewis, DI, Lilley, EJ, Longridge, ER, McLeod, CM, Miele, M, Nelson, NC, Ormandy, EH, Pallett, H, Poort, L, Pound, P, Ramsden, E, Roe, E, Scalway, H, Schrader, A, Scotton, CJ, Scudamore, CL, Smith, JA, Whitfield, L and Wolfensohn, Sarah (2016) Developing a Collaborative Agenda for Humanities and Social Scientific Research on Laboratory Animal Science and Welfare PLOS ONE, 11 (7), e0158791.

Wu, H, von Kamp, A, Leoncikas, V, Mori, W, Sahin, N, Gevorgyan, A, Linley, C, Grabowski, M, Mannan, AA, Stoy, N, Stewart, GR, Ward, LT, Lewis, DJM, Sroka, J, Matsuno, H, Klamt, S, Westerhoff, HV, McFadden, J, Plant, NJ and Kierzek, AM (2016) MUFINS: Multi-Formalism Interaction Network Simulator npj Systems Biology and Applications.

Ippolito, G, Lanini, S, Brouqui, P, Di Caro, A, Vairo, F, Abdulla, S, Fusco, FM, Krishna, S, Capobianchi, MR, Kyobe-Bosa, H, Lewis, DJM, Puro, V, Wolfel, R, Avsic-Zupanc, T, Dar, O, Mwaba, P, Bates, M, Heymann, D and Zumla, A (2015) Ebola: missed opportunities for Europe-Africa research LANCET INFECTIOUS DISEASES, 15 (11). pp. 1254-1255.

Ma, JK-C, Drossard, J, Lewis, D, Altmann, F, Boyle, J, Christou, P, Cole, T, Dale, P, van Dolleweerd, CJ, Isitt, V, Katinger, D, Lobedan, M, Mertens, H, Paul, MJ, Rademacher, T, Sack, M, Hundleby, PAC, Stiegler, G, Stoger, E, Twyman, RM, Vcelar, B and Fischer, R (2015) Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants PLANT BIOTECHNOLOGY JOURNAL, 13 (8). pp. 1106-1120.

Della Cioppa, G, Jonsdottir, I and Lewis, D (2015) Challenges in early clinical development of adjuvanted vaccines VACCINE, 33. B47-B51.

Struyf, F, Colau, B, Wheeler, CM, Naud, P, Garland, S, Quint, W, Chow, S-N, Salmeron, J, Lehtinen, M, Del Rosario-Raymundo, MR, Paavonen, J, Teixeira, JC, Julieta Germar, M, Peters, K, Skinner, SR, Limson, G, Castellsague, X, Poppe, WAJ, Ramjattan, B, Klein, TD, Schwarz, TF, Chatterjee, A, Tjalma, WAA, Diaz-Mitoma, F, Lewis, DJM, Harper, DM, Molijn, A, van Doorn, L-J, David, M-P and Dubin, G (2015) Post Hoc Analysis of the PATRICIA Randomized Trial of the Efficacy of Human Papillomavirus Type 16 (HPV-16)/HPV-18 AS04-Adjuvanted Vaccine against Incident and Persistent Infection with Nonvaccine Oncogenic HPV Types Using an Alternative Multiplex Type-Specific PCR Assay for HPV DNA CLINICAL AND VACCINE IMMUNOLOGY, 22 (2). pp. 235-244.

Lewis, DJM and Lythgoe, MP (2015) Application of "Systems Vaccinology" to Evaluate Inflammation and Reactogenicity of Adjuvanted Preventative Vaccines JOURNAL OF IMMUNOLOGY RESEARCH, ARTN 90940.

Smith, NR, Lewis, DJ, Fahy, A, Eldridge, S, Taylor, SJ, Moore, DG, Clark, C, Stansfeld, SA and Cummins, S (2015) Individual socio-demographic factors and perceptions of the environment as determinants of inequalities in adolescent physical and psychological health: the Olympic Regeneration in East London (ORiEL) study. BMC Public Health, 15.

Read, RC, Baxter, D, Chadwick, DR, Faust, SN, Finn, A, Gordon, SB, Heath, PT, Lewis, DJM, Pollard, AJ, Turner, DPJ, Bazaz, R, Ganguli, A, Havelock, T, Neal, KR, Okike, IO, Morales-Aza, B, Patel, K, Snape, MD, Williams, J, Gilchrist, S, Gray, SJ, Maiden, MCJ, Toneatto, D, Wang, H, McCarthy, M, Dull, PM and Borrow, R (2014) Effect of a quadrivalent meningococcal ACWY glycoconjugate or a serogroup B meningococcal vaccine on meningococcal carriage: an observer-blind, phase 3 randomised clinical trial LANCET, 384 (9960). pp. 2123-2131.

Lewis, DJM, Wang, Y, Huo, Z, Giemza, R, Babaahmady, K, Rahman, D, Shattock, RJ, Singh, M and Lehner, T (2014) Effect of Vaginal Immunization with HIVgp140 and HSP70 on HIV-1 Replication and Innate and T Cell Adaptive Immunity in Women JOURNAL OF VIROLOGY, 88 (20). pp. 11648-11657.

Kaufmann, SH, Juliana McElrath, M, Lewis, DJ and Del Giudice, G (2014) Challenges and responses in human vaccine development. Curr Opin Immunol, 28C. pp. 18-26.

Coggeshall, JD, Lewis, DD, Fitzpatrick, N, Conrad, BP, Swanson, KR, Kim, SE, Palm, LS, Tremolada, G and Pozzi, A (2014) Biomechanical Comparison of Two Implants for the Stabilization of Incomplete Ossification of the Humeral Condyle Lesions in Dogs VETERINARY SURGERY, 43 (1). pp. 58-65.

Gan, C, Mostafid, H, Khan, MS and Lewis, DJM (2013) BCG immunotherapy for bladder cancer-the effects of substrain differences NATURE REVIEWS UROLOGY, 10 (10). pp. 580-588.

Aggerbeck, H, Tingskov, PN, Joshi, P, Boyle, J, Lewis, DJM, Giemza, R, Hoff, ST and Andersen, P (2013) Randomised Clinical Trial Investigating the Specificity of a Novel Skin Test (C-Tb) for Diagnosis of M. tuberculosis Infection PLoS ONE, 8 (5).

Mastelic, B, Lewis, DJM, Golding, H, Gust, I, Sheets, R and Lambert, P-H (2013) Potential use of inflammation and early immunological event biomarkers in assessing vaccine safety BIOLOGICALS, 41 (2). pp. 115-124.

Kordbacheh, T, Tringham, J, Whyte, MB, Schulte, KM, Izatt, L and Lewis, D (2013) Extended family pedigree with hereditary phaeochromocytoma due to a MAX mutation: novel associations with Wilm’s tumour and other malignancies Endocrine Abstracts.

Edmund, GH, Lewis, DF and Howlin, BJ (2013) Modelling species selectivity in rat and human cytochrome P450 2D enzymes. PLoS One, 8 (5).

Pollard, AJ, Savulescu, J, Oxford, J, Hill, AVS, Levine, MM, Lewis, DJM, Read, RC, Graham, DY, Sun, W, Openshaw, P and Gordon, SB (2012) Human microbial challenge: the ultimate animal model LANCET INFECTIOUS DISEASES, 12 (12). pp. 903-905.

Katinger, D, Jeffs, S, Altmann, F, Cope, A, McKay, P, Almond, N, Sandstrom, E, Hejdeman, B, Biberfeld, G, Nilsson, C, Hallengard, D, Wahren, B, Lehner, T, Singh, M, Lewis, DJ, Lacey, C and Shattock, R (2012) CN54gp140: product characteristics, peclinical and clinical use - recombinant glycoprotein for HIV immunization RETROVIROLOGY, 9, ARTN P351.

Katinger, D, Wagner, A, Luque, I, Crespillo, S, Conejero-Lara, F, Roger, M, Martin, C, Mouz, N, Mourao, S, Farsang, A, Notka, F, Malcolm, K, Bosquet, N, Le Grand, R, Moog, C, Cope, A, Shattock, R, Lewis, DJ and El Habib, R (2012) Liposomal formulation of Gp41 derivate with adjuvant MPLA: vaccine design, immunogenicity in animals and safety in humans RETROVIROLOGY, 9, ARTN P354.

Smith, NR, Clark, C, Fahy, AE, Tharmaratnam, V, Lewis, DJ, Thompson, C, Renton, A, Moore, DG, Bhui, KS, Taylor, SJC, Eldridge, S, Petticrew, M, Greenhalgh, T, Stansfeld, SA and Cummins, S (2012) The Olympic Regeneration in East London (ORiEL) study: Protocol for a prospective controlled quasi-experiment to evaluate the impact of urban regeneration on young people and their families BMJ Open, 2 (4).

Kumar, N and Lewis, DJ (2012) Fever and rash in a returning traveller. BMJ, 344.

Vaca, M, Moncayo, AL, Cosgrove, CA, Chico, ME, Castello-Branco, LR, Lewis, DJ and Cooper, PJ (2012) A Single Dose of Oral BCG Moreau Fails to Boost Systemic IFN-γ Responses to Tuberculin in Children in the Rural Tropics: Evidence for a Barrier to Mucosal Immunization. J Trop Med, 2012.

Huo, Z, Bissett, SL, Giemza, R, Beddows, S, Oeser, C and Lewis, DJ (2012) Systemic and mucosal immune responses to sublingual or intramuscular human papilloma virus antigens in healthy female volunteers. PLoS One, 7 (3), e33736.

Zhang, T, Liu, LA, Lewis, DFV and Wei, D-Q (2011) Long-Range Effects of a Peripheral Mutation on the Enzymatic Activity of Cytochrome P450 1A2 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 51 (6). pp. 1336-1346.

Reina Ortiz, M, Schreiber, F, Benitez, S, Broncano, N, Chico, ME, Vaca, M, Alexander, N, Lewis, DJ, Dougan, G and Cooper, PJ (2011) Effects of Chronic Ascariasis and Trichuriasis on Cytokine Production and Gene Expression in Human Blood: A Cross-Sectional Study PLOS NEGLECTED TROPICAL DISEASES, 5 (6), ARTN e1157.

Lewis, DJ, Fraser, CA, Mahmoud, AN, Wiggins, RC, Woodrow, M, Cope, A, Cai, C, Giemza, R, Jeffs, SA and Manoussaka, M (2011) Phase I randomised clinical trial of an HIV-1(CN54), clade C, trimeric envelope vaccine candidate delivered vaginally. PLoS One, 6 (9).

Clark, SO, Kelly, DLF, Badell, E, Castello-Branco, LR, Aldwell, F, Winter, N, Lewis, DJM and Marsh, PD (2010) Oral delivery of BCG Moreau Rio de Janeiro gives equivalent protection against tuberculosis but with reduced pathology compared to parenteral BCG Danish vaccination VACCINE, 28 (43). pp. 7109-7116.

Lewis, DFV, Ito, Y and Lake, BG (2010) Quantitative structure-activity relationships (QSARs) for inhibitors and substrates of CYP2B enzymes: importance of compound lipophilicity in explanation of potency differences JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 25 (5). pp. 679-684.

Schreiber, F, Huo, Z, Giemza, R, Woodrow, M, Fenner, N, Stephens, Z, Dougan, G, Prideaux, S, Castello-Branco, LR and Lewis, DJ (2010) An investigation of clinical and immunological events following repeated aerodigestive tract challenge infections with live Mycobacterium bovis Bacille Calmette Guérin. Vaccine, 28 (33). pp. 5427-5431.

Lewis, DFV, Ito, Y, Eddershaw, PJ, Dickins, M and Goldfarb, PS (2010) An evaluation of ondansetron binding interactions with human cytochrome P450 enzymes CYP3A4 and CYP2D6 Drug Metabolism Letters, 4 (1). pp. 25-30.

Lewis, DFV and Ito, Y (2010) Human CYPs involved in drug metabolism: structures, substrates and binding affinities EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 6 (6). pp. 661-674.

Kirkby, KA, Wheeler, JL, Farese, JP, Ellison, GW, Bacon, NJ, Sereda, CW and Lewis, DD (2010) Vacuum-assisted wound closure: Clinical applications Compendium: Continuing Education For Veterinarians, 32 (3).

Kirkby, KA, Wheeler, JL, Farese, JP, Ellison, GW, Bacon, NJ, Sereda, CW and Lewis, DD (2010) Surgical views: Vacuum-assisted wound closure: clinical applications. Compend Contin Educ Vet, 32 (3). E1-E6.

Carr, I and Lewis, D (2010) Combating corruption through employment law and whistleblower protection Industrial Law Journal, 39 (1). pp. 52-81.

Kirkby, KA, Wheeler, JL, Farese, JP, Ellison, GW, Bacon, NJ, Sereda, CW and Lewis, DD (2009) Vacuum-Assisted Wound Closure: Application and Mechanism of Action COMPENDIUM-CONTINUING EDUCATION FOR VETERINARIANS, 31 (12). 568-+.

Kirkby, K, Wheeler, J, Farese, J, Ellison, G, Bacon, N, Sereda, C and Lewis, D (2009) Surgical views: Vacuum-assisted wound closure: application and mechanism of action. Compend Contin Educ Vet, 31 (12). E1-E7.

Domingos, MO, Andrade, RG, Barbaro, KC, Borges, MM, Lewis, DJ and New, RRC (2009) Influence of the A and B subunits of cholera toxin (CT) and Escherichia coli toxin (IT) on TNF-alpha release from macrophages TOXICON, 53 (5). pp. 570-577.

Lewis, DF, Ito, Y and Lake, BG (2009) Electronic and structural aspects of p450-mediated drug metabolism. Drug Metab Lett, 3 (2). pp. 87-100.

Launay, O, Sadorge, C, Jolly, N, Poirier, B, Bechet, S, van der Vliet, D, Seffer, V, Fenner, N, Dowling, K, Giemza, R, Johnson, J, Ndiaye, A, Vray, M, Sansonetti, P, Morand, P, Poyart, C, Lewis, D and Gougeon, M-L (2009) Safety and immunogenicity of SC599, an oral live attenuated Shigella dysenteriae type-1 vaccine in healthy volunteers: Results of a Phase 2, randomized, double-blind placebo-controlled trial VACCINE, 27 (8). pp. 1184-1191.

Lewis, DJM (2009) Unnecessary universal BCG in UK Efficacy of BCG: three quarters full or one quarter empty? BRITISH MEDICAL JOURNAL, 338, ARTN b635.

Lewis, DFV and Ito, Y (2009) Human P450s involved in drug metabolism and the use of structural modelling for understanding substrate selectivity and binding affinity XENOBIOTICA, 39 (8). pp. 625-635.

Badell, E, Nicolle, F, Clark, S, Majlessi, L, Boudou, F, Martino, A, Castello-Branco, L, Leclerc, C, Lewis, DJM, Marsh, PD, Gicquel, B and Winter, N (2009) Protection against tuberculosis induced by oral prime with Mycobacterium bovis BCG and intranasal subunit boost based on the vaccine candidate Ag85B-ESAT-6 does not correlate with circulating IFN-gamma producing T-cells VACCINE, 27 (1). pp. 28-37.

Lewis, DF, Ito, Y and Lake, BG (2009) Molecular modelling of CYP2F substrates: comparison of naphthalene metabolism by human, rat and mouse CYP2F subfamily enzymes. Drug Metabol Drug Interact, 24 (2-4). pp. 229-257.

Lewis, DJ, Lacey, CJ, Jeffs, S, Cole, T, Fraser, C, Wiggins, R, Woodrow, M, Cope, A, Cai, C, Giemza, E, Mahmhoud, A, Katinger, D, Cranage, M and Shattock, R (2009) P14-06. Phase 1 safety and immunogenicity randomised controlled trial of a vaginal gp140 vaccine Retrovirology, 6 (SUPPL.).

Lewis, DJ, Huo, Z, Barnett, S, Kromann, I, Giemza, R, Galiza, E, Woodrow, M, Thierry-Carstensen, B, Andersen, P and Novicki, D (2009) Transient facial nerve paralysis (Bell's palsy) following intranasal delivery of a genetically detoxified mutant of Escherichia coli heat labile toxin. PLoS One, 4 (9).

Lewis, DFV and Ito, Y (2008) Human cytochromes P450 in the metabolism of drugs: new molecular models of enzyme-substrate interactions EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 4 (9). pp. 1181-1186.

Lewis, DFV, Ito, Y and Goldfarb, PS (2008) Enzyme-substrate binding interaction energies and their application to the cytochrome P450 system CURRENT COMPUTER-AIDED DRUG DESIGN, 4 (2). pp. 111-122.

Sadorge, C, Ndiaye, A, Beveridge, N, Frazer, S, Giemza, R, Jolly, N, Johnson, J, Liddy, H, Cosgrove, CA, Allavena, P, Mantovani, A, Bechet, S, Fontaine-Thompson, A, Griffin, GE, Dupont, F, Sansonetti, PJ and Lewis, DJM (2008) Phase 1 clinical trial of live attenuated Shigella dysenteriae type-1 Delta icsA Delta ent Delta fep Delta stxA : HgR oral vaccine SC599 in healthy human adult volunteers VACCINE, 26 (7). pp. 978-987.

Ito, Y, Kondo, H, Goldfarb, PS and Lewis, DFV (2008) Analysis of CYP2D6 substrate interactions by computational methods JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 26 (6). pp. 947-956.

Pushparajah, DS, Umachandran, M, Nazir, T, Plant, KE, Plant, N, Lewis, DFV and Ioannides, C (2008) Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size TOXICOLOGY IN VITRO, 22 (1). pp. 128-145.

Fitzpatrick, N, Lewis, D and Cross, A (2008) A biomechanical comparison of external skeletal fixation and plating for the stabilization of ilial osteotomies in dogs VETERINARY AND COMPARATIVE ORTHOPAEDICS AND TRAUMATOLOGY, 21 (4). pp. 349-357.

Tseng, J-C, Don, M-J, Lewis, DFV, Wang, S-Y and Ueng, Y-F (2007) Inhibition of CYP1 by 7,8-dehydrorutaecarpine and its methoxylated derivatives JOURNAL OF FOOD AND DRUG ANALYSIS, 15 (4). pp. 480-487.

Khan, S, Chatfield, S, Stratford, R, Bedwell, J, Bentley, M, Sulsh, S, Giemza, R, Smith, S, Bongard, E, Cosgrove, CA, Johnson, J, Dougan, G, Griffin, GE, Makin, J and Lewis, DJM (2007) Ability of SP12 mutant of S. typhi to effectively induce antibody responses to the mucosal antigen enterotoxigenic E. coli heat labile toxin B subunit after oral delivery to humans VACCINE, 25 (21). pp. 4175-4182.

Wiseman, A and Lewis, DFV (2007) 57-isoform cytochromes P450 for bioconversions ENZYME AND MICROBIAL TECHNOLOGY, 40 (6). pp. 1469-1474.

Lewis, DFV, Lake, BG and Dickins, M (2007) Quantitative structure-activity relationships (QSARs) in inhibitors of various cytochromes P450: The importance of compound lipophilicity JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 22 (1). pp. 1-6.

Nong, A, Charest-Tardif, G, Tardif, R, Lewis, DFV, Sweeney, LM, Gargas, ML and Krishnan, K (2007) Physiologically based modeling of the inhalation pharmacokinetics of ethylbenzene in B6C3F1 mice JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 70 (21). pp. 1838-1848.

Lewis, DFV, Ito, Y and Goldfarb, PS (2006) Investigating human p450s involved in drug metabolism via homology with high-resolution p450 crystal structures of the CYP2C subfamily CURRENT DRUG METABOLISM, 7 (6). pp. 589-598.

Lewis, DFV, Lake, BG, Ito, Y and Dickins, M (2006) Lipophilicity relationships in inhibitors of CYP2C9 and CYP2C19 enzymes JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 21 (4). pp. 385-389.

Lewis, DFV and Dorne, J-LCM (2006) The astronomical pulse of global extinction events THESCIENTIFICWORLDJOURNAL, 6. pp. 718-726.

Cosgrove, CA, Castello-Branco, LRR, Hussell, T, Sexton, A, Giemza, R, Phillips, R, Williams, A, Griffin, GE, Dougan, G and Lewis, DJM (2006) Boosting of cellular immunity against Mycobacterium tuberculosis and modulation of skin cytokine responses in healthy human volunteers by Mycobacterium bovis BCG substrain moreau Rio de Janeiro oral vaccine INFECTION AND IMMUNITY, 74 (4). pp. 2449-2452.

Lewis, DFV, Lake, BG and Dickns, M (2006) Quantitative structure-activity relationships (QSARs) in CYP3A4 inhibitors: The importance of lipophilic character and hydrogen bonding JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 21 (2). pp. 127-132.

Lewis, DFV, Ito, Y and Lake, BG (2006) Metabolism of coumarin by human P450s: A molecular modelling study TOXICOLOGY IN VITRO, 20 (2). pp. 256-264.

Lewis, DFV, Ito, Y and Goldfarb, PS (2006) Structural modelling of the human drug-metabolizing cytochromes P450 CURRENT MEDICINAL CHEMISTRY, 13 (22). pp. 2645-2652.

Lewis, DF, Lake, BG, Ito, Y and Anzenbacher, P (2006) Quantitative structure-activity relationships (QSARs) within cytochromes P450 2B (CYP2B) subfamily enzymes: the importance of lipophilicity for binding and metabolism. Drug Metabol Drug Interact, 21 (3-4). pp. 213-231.

Huo, ZM, Sinha, R, McNeela, EA, Borrow, R, Giemza, R, Cosgrove, C, Heath, PT, Mills, KHG, Rappuoli, R, Griffin, GE and Lewis, DJM (2005) Induction of protective serum meningococcal bactericidal and diphtheria-neutralizing antibodies and mucosal immunoglobulin a in volunteers by nasal insufflations of the Neisseria meningitidis serogroup C polysaccharide-CRM197 conjugate vaccine mixed with chitosan INFECTION AND IMMUNITY, 73 (12). pp. 8256-8265.

Lewis, DFV, Ito, Y and Goldfarb, PS (2005) Cytochrome P450 structures and their substrate interactions DRUG DEVELOPMENT RESEARCH, 66 (1). pp. 19-24.

McNeela, EA, Jabbal-Gill, I, Illum, L, Pizza, M, Rappuoli, R, Podda, A, Lewis, DJM and Mills, KHG (2004) Intranasal immunization with genetically detoxified diphtheria toxin induces T cell responses in humans: enhancement of Th2 responses and toxin-neutralizing antibodies by formulation with chitosan VACCINE, 22 (8). pp. 909-914.

Ioannides, C and Lewis, DFV (2004) Cytochromes P450 in the bioactivation of chemicals CURRENT TOPICS IN MEDICINAL CHEMISTRY, 4 (16). pp. 1767-1788.

Lewis, DJ, Eiden, JE, Goilav, C, Langenberg, AG, Suggett, F and Griffin, GE (2003) Rapid and frequent induction of protective immunity exceeding UK recommendations for healthcare settings by MF59-adjuvated hepatitis B vaccine. Commun Dis Public Health, 6 (4). pp. 320-324.

Domingos, MO, Barbaro, KC, Tynan, W, Penny, J, Lewis, DJM and New, RRC (2003) Influence of sphingomyelin and TNF-alpha release on lethality and local inflammatory reaction induced by Loxosceles gaucho spider venom in mice TOXICON, 42 (5). pp. 471-479.

Domingos, MO, Tynan, W, Barbaro, KC, Penny, J, Lewis, DJM and New, RRC (2003) Effect of Loxosceles gaucho venom on cell morphology and behaviour in vitro in the presence and absence of sphingomyelin TOXICON, 42 (4). pp. 439-445.

Simmons, CP, Clare, S, Ghaem-Maghami, M, Uren, TK, Rankin, J, Huett, A, Goldin, R, Lewis, DJ, MacDonald, TT, Strugnell, RA, Frankel, G and Dougan, G (2003) Central role for B lymphocytes and CD4(+) T cells in immunity to infection by the attaching and effacing pathogen Citrobacter rodentium INFECTION AND IMMUNITY, 71 (9). pp. 5077-5086.

Ghaem-Maghami, S, Ratti, G, Ghaem-Maghami, M, Comanducci, M, Hay, PE, Bailey, RL, Mabey, DCW, Whittle, HC, Ward, ME and Lewis, DJM (2003) Mucosal and systemic immune responses to plasmid protein pgp3 in patients with genital and ocular Chlamydia trachomatis infection CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 132 (3). pp. 436-442.

Tagliabue, A, Cesaroni, MP and Lewis, DJM (2003) Novel human vaccine strategies and the 5th Framework Programme: pushing the envelope VACCINE, 21. S121-S127.

Mills, KHG, Cosgrove, C, McNeela, EA, Sexton, A, Giemza, R, Jabbal-Gill, I, Church, A, Lin, W, Illum, L, Podda, A, Rappuoli, R, Pizza, M, Griffin, GE and Lewis, DJM (2003) Protective levels of diphtheria-neutralizing antibody induced in healthy volunteers by unilateral priming-boosting intranasal immunization associated with restricted ipsilateral mucosal secretory immunoglobulin a INFECTION AND IMMUNITY, 71 (2). pp. 726-732.

Lewis, DFV, Ioannides, C and Parke, DV (2003) A quantitative structure-activity relationship (QSAR) study of mutagenicity in several series of organic chemicals likely to be activated by cytochrome P450 enzymes TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS. pp. 187-193.

Lewis, DJ and Hayward, CM (2003) Stimulation of mucosal immunity. Methods Mol Med, 87. pp. 245-254.

Hindle, Z, Chatfield, SN, Phillimore, J, Bentley, M, Johnson, J, Cosgrove, CA, Ghaem-Maghami, M, Sexton, A, Khan, M, Brennan, FR, Everest, P, Wu, T, Pickard, D, Holden, DW, Dougan, G, Griffin, GE, House, D, Santangelo, JD, Khan, SA, Shea, JE, Feldman, RG and Lewis, DJ (2002) Characterization of Salmonella enterica derivatives harboring defined aroC and Salmonella pathogenicity island 2 type III secretion system (ssaV) mutations by immunization of healthy volunteers. Infect Immun, 70 (7). pp. 3457-3467.

Skene, DJ, Papagiannidou, E, Hashemi, E, Snelling, J, Lewis, DFV, Fernandez, M and Ioannides, C (2001) Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices JOURNAL OF PINEAL RESEARCH, 31 (4). pp. 333-342.

Goncalves, NS, Ghaem-Maghami, M, Monteleone, G, Frankel, G, Dougan, G, Lewis, DJM, Simmons, CP and MacDonald, TT (2001) Critical role for tumor necrosis factor alpha in controlling the number of lumenal pathogenic bacteria and immunopathology in infectious colitis INFECTION AND IMMUNITY, 69 (11). pp. 6651-6659.

Ghaem-Maghami, M, Simmons, CP, Daniell, S, Pizza, M, Lewis, D, Frankel, G and Dougan, G (2001) Intimin-specific immune responses prevent bacterial colonization by the attaching-effacing pathogen Citrobacter rodentium INFECTION AND IMMUNITY, 69 (9). pp. 5597-5605.

Lewis, DFV, Ioannides, C, Parke, DV and Schulte-Hermann, R (2000) Quantitative structure-activity relationships in a series of endogenous and synthetic steroids exhibiting induction of CYP3A activity and hepatomegaly associated with increased DNA synthesis JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 74 (4). pp. 179-185.

Whitty, CJM, Macallan, DC and Lewis, DJM (2000) Use of BCG vaccination LANCET, 356 (9241). pp. 1609-1610.

Tubridy, N, Wells, C, Lewis, D and Schon, F (2000) Unsuccessful treatment with cidofovir and cytarabine in progressive multifocal leukoencephalopathy associated with dermatomyositis JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 93 (7). pp. 374-375.

Douce, G, Giannelli, V, Pizza, M, Lewis, D, Everest, P, Rappuoli, R and Dougan, G (1999) Genetically detoxified mutants of heat-labile toxin from Escherichia coli are able to act as oral adjuvants INFECTION AND IMMUNITY, 67 (9). pp. 4400-4406.

Ghaem-Maghami, S and Lewis, DJM (1999) Chlamydia trachomatis: the role of cellular and humoral immune mechanisms in the development of blindness CURRENT OPINION IN INFECTIOUS DISEASES, 12 (3). pp. 229-233.

Hayward, CMM, O'Gaora, P, Young, DB, Griffin, GE, Thole, J, Hirst, TR, Castello-Branco, LRR and Lewis, DJM (1999) Construction and murine immunogenicity of recombinant Bacille Calmette Guerin vaccines expressing the B subunit of Escherichia coli heat labile enterotoxin VACCINE, 17 (9-10). pp. 1272-1281.

Lewis, DFV, Ioannides, C and Parke, DV (1998) Cytochromes P450 and species differences in xenobiotic metabolism and activation of carcinogen ENVIRONMENTAL HEALTH PERSPECTIVES, 106 (10). pp. 633-641.

Ortigao-deo-Sampaio, MB, Shattock, RJ, Hayes, P, Griffin, GE, Linhares-de-Carvalho, MI, de Leon, AP, Lewis, DJM and Castello-Branco, RR (1998) Increase in plasma viral load after oral cholera immunization of HIV-infected subjects AIDS, 12 (14). F145-F150.

Douds, AC, Lewis, DJM, Lim, AG, Maxwell, JD and Poulton, TA (1998) Serum IgA antibodies to human gut luminal aspirates and human liver in alcoholic liver disease ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 22 (7). pp. 1383-1388.

Lewis, DFV, Ioannides, C and Parke, DV (1998) A combined COMPACT and HazardExpert study of 40 chemicals for which information on mutagenicity and carcinogenicity is known, including the results of human epidemiological studies HUMAN & EXPERIMENTAL TOXICOLOGY, 17 (10). pp. 577-586.

Fielder, M and Lewis, DJ (1998) Vaccination against bacterial gut infections. Curr Opin Infect Dis, 11 (5). pp. 591-596.

Lewis, DFV, Ioannides, C and Parke, DV (1998) Further evaluation of COMPACT, the molecular orbital approach for the prospective safety evaluation of chemicals MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 412 (1). pp. 41-54.

Lewis, DFV, Ioannides, C and Parke, DV (1998) An improved and updated version of the compact procedure for the evaluation of P450-mediated chemical activation DRUG METABOLISM REVIEWS, 30 (4). pp. 709-737.

GhaemMaghami, S, Bailey, RL, Mabey, DCW, Hay, PE, Mahdi, OSM, Joof, HM, Whittle, HC, Ward, ME and Lewis, DJM (1997) Characterization of B-cell responses to Chlamydia trachomatis antigens in humans with trachoma INFECTION AND IMMUNITY, 65 (12). pp. 4958-4964.

Cheung, YL, Lewis, DFV, Ridd, TI, Gray, TJB and Ioannides, C (1997) Diaminonaphthalenes and related aminocompounds: Mutagenicity, CYP1A induction and interaction with the Ah receptor TOXICOLOGY, 118 (2-3). pp. 115-127.

Lewis, DFV, Brantom, PG, Ioannides, C, Walker, R and Parke, DV (1997) Nitrosamine carcinogenesis: Rodent assays, quantitative structure-activity relationships, and human risk assessment DRUG METABOLISM REVIEWS, 29 (4). pp. 1055-1078.

Lewis, DFV, Ioannides, C and Parke, DV (1996) COMPACT and molecular structure in toxicity assessment: A prospective evaluation of 30 chemicals currently being tested for rodent carcinogenicity by the NCI/NTP ENVIRONMENTAL HEALTH PERSPECTIVES, 104. pp. 1011-1016.

CastelloBranco, LRR, Lewis, DJM, OrtigaodeSampaio, MB and Griffin, GE (1996) Gastrointestinal immune responses in HIV infected subjects MEMORIAS DO INSTITUTO OSWALDO CRUZ, 91 (3). pp. 363-366.

Howell, NK, Yeboah, NA and Lewis, DFV (1995) Studies on the electrostatic interactions of lysozyme with alpha-lactalbumin and beta-lactoglobulin INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 30 (6). pp. 813-824.

Ioannides, C, Lewis, DF and Parke, DV (1993) Computer modelling in predicting carcinogenicity. Eur J Cancer Prev, 2 (3). pp. 275-282.

McKirdy, HC, Lowndes, R, Swift, GL, Davies, HA, Lewis, D and Rhodes, J (1992) The oesophagus and chest pain. Lancet, 339 (8800). pp. 1049-1050.

Parke, AL, Ioannides, C, Lewis, DFV and Parke, DV (1991) Molecular pathology of drug-disease interactions in chronic autoimmune inflammatory diseases Inflammopharmacology, 1 (1). pp. 3-36.

Parke, DV, Ioannides, C, Lewis, DF and Obrebska-Parke, MJ (1990) Current problems in the evaluation of chemical safety. Pol J Occup Med, 3 (1). pp. 15-41.

Ioannides, C, Lewis, DF, Trinick, J, Neville, S, Sertkaya, NN, Kajbaf, M and Gorrod, JW (1989) A rationale for the non-mutagenicity of 2- and 3-aminobiphenyls. Carcinogenesis, 10 (8). pp. 1403-1407.

Lewis, DF, Ioannides, C and Parke, DV (1987) Structural requirements for substrates of cytochromes P-450 and P-448. Chem Biol Interact, 64 (1-2). pp. 39-60.

Conference or Workshop Item

Lehner, T, Lewis, D, Wang, Y, Huo, Z, Giemza, R, Babaahmady, K, Rahman, D, Shattock, R and Singh, M (2014) The effect of vaginal immunization in women with HIVgp140 and HSP70 on HIV-1 replication, innate and T cell adaptive immunity In: 16th Annual International Meeting of the Institute-of-Human-Virology (IHV), 2014-09-14 - 2014-09-14, Univ Maryland Sch Med, Baltimore, MD.

Cope, AV, Moog, C, Shattock, RJ, Chawda, MM, Czyzewska-Khan, J, Kat, P, Venables, S, Yan, C, Williams, M, Cobb, K, Singh, M, Oehlmann, W, Elamin, A, Katinger, D, Wagner, A, Joshi, P and Lewis, DJM (2014) A Phase I Clinical Trial with a Novel gp41 HIV Vaccine (EN41-FPA2) in Healthy Female Volunteers: A Mucosal Prime and Intramuscular Boost Regimen In: Symposium on HIV Research for Prevention (HIV R4P), 2014-10-28 - 2014-10-31, Cape Town, SOUTH AFRICA.


Lewis, David Francis Victor (1981) Molecular Orbital Calculations in the Study of Cancer and Chemotherapy Doctoral thesis, University of Surrey.

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