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Items where Author is "Laing, E"

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Article

Laing, Emma, Moller-Levet, Carla, Poh, Norman, Santhi, Nayantara, Archer, Simon and Dijk, Derk-Jan (2017) Title: Blood transcriptome based biomarkers for human circadian phase eLife. pp. 1-26.

Freire Martín, I, Thomas, CM, Laing, E, AbuOun, M, La Ragione, RM and Woodward, MJ (2016) Curing vector for IncI1 plasmids and its use to provide evidence for a metabolic burden of IncI1 CTX-M-1 plasmid pIFM3791 on Klebsiella pneumoniae Journal of Medical Microbiology, 65. pp. 611-618.

Matia-González, AM, Laing, EE and Gerber, AP (2015) Conserved mRNA-binding proteomes in eukaryotic organisms Nature Structural and Molecular Biology, 22 (12). pp. 1027-1033.

Laing, Emma, Johnston, Jonathan, Moller-Levet, Carla, Bucca, G, Smith, CP, Dijk, Derk-Jan and Archer, Simon (2015) Exploiting human and mouse transcriptomic data: Identification of circadian genes and pathways influencing health BioEssays, 37 (5). pp. 544-556.

Swiatek-Polatynska, MA, Bucca, G, Laing, E, Gubbens, J, Titgemeyer, F, Smith, CP, Rigali, S and van Wezel, GP (2015) Genome-Wide Analysis of In Vivo Binding of the Master Regulator DasR in Streptomyces coelicolor Identifies Novel Non-Canonical Targets PLOS ONE, 10 (4), ARTN e.

Rahman, T, Mahapatra, M, Laing, E and Jin, Y (2015) Evolutionary non-linear modelling for selecting vaccines against antigenically variable viruses BIOINFORMATICS, 31 (6). pp. 834-840.

Romero, DA, Hasan, AH, Lin, Y-F, Kime, L, Ruiz-Larrabeiti, O, Urem, M, Bucca, G, Mamanova, L, Laing, EE, van Wezel, GP, Smith, CP, Kaberdin, VR and McDowall, KJ (2014) A comparison of key aspects of gene regulation in Streptomyces coelicolor and Escherichia coli using nucleotide-resolution transcription maps produced in parallel by global and differential RNA sequencing MOLECULAR MICROBIOLOGY, 94 (5). pp. 963-987.

Wagley, S, Newcombe, J, Laing, E, Yusuf, E, Sambles, CM, Studholme, DJ, La Ragione, RM, Titball, RW and Champion, OL (2014) Differences in carbon source utilisation distinguish Campylobacter jejuni from Campylobacter coli. BMC Microbiology, 14.

Hasan, S, van der Veen, DR, Winsky-Sommerer, R, Hogben, A, Laing, EE, Koentgen, F, Dijk, DJ and Archer, SN (2014) A human sleep homeostasis phenotype in mice expressing a primate-specific PER3 variable-number tandem-repeat coding-region polymorphism. FASEB J.

Rico, S, Santamaría, RI, Yepes, A, Rodríguez, H, Laing, E, Bucca, G, Smith, CP and Díaz, M (2014) Deciphering the regulon of the Streptomyces coelicolor AbrC3, a positive response regulator of antibiotic production. Appl Environ Microbiol.

Archer, SN, Laing, EE, Möller-Levet, CS, van der Veen, DR, Bucca, G, Lazar, AS, Santhi, N, Slak, A, Kabiljo, R, von Schantz, M, Smith, CP and Dijk, DJ (2014) Mistimed sleep disrupts circadian regulation of the human transcriptome. Proc Natl Acad Sci U S A.

Möller-Levet, CS, Archer, SN, Bucca, G, Laing, EE, Slak, A, Kabiljo, R, Lo, JC, Santhi, N, von Schantz, M, Smith, CP and Dijk, DJ (2013) Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome. Proc Natl Acad Sci U S A, 110 (12). E1132-E1141.

Swiatek, MA, Gubbens, J, Bucca, G, Song, E, Yang, YH, Laing, E, Kim, BG, Smith, CP and van Wezel, GP (2013) The ROK-family regulator Rok7B7 pleiotropicaly affects xylose utilization, carbon catabolite repression and antibiotic production in Streptomyces coelicolor. J Bacteriol, 195 (6). pp. 1236-1248.

Salerno, P, Persson, J, Bucca, G, Laing, E, Ausmees, N, Smith, CP and Flärdh, K (2013) Identification of new developmentally regulated genes involved in Streptomyces coelicolor sporulation. BMC Microbiol, 13.

Thomas, SA, Jin, Y, Laing, E and Smith, CP (2013) Reconstructing regulatory networks in Streptomyces using evolutionary algorithms 2013 13th UK Workshop on Computational Intelligence, UKCI 2013. pp. 24-30.

Allenby, NE, Laing, E, Bucca, G, Kierzek, AM and Smith, CP (2012) Diverse control of metabolism and other cellular processes in Streptomyces coelicolor by the PhoP transcription factor: genome-wide identification of in vivo targets. Nucleic Acids Res.

Bonde, BK, Beste, DJV, Laing, E, Kierzek, AM and McFadden, J (2011) Differential Producibility Analysis (DPA) of Transcriptomic Data with Metabolic Networks: Deconstructing the Metabolic Response of M. tuberculosis PLOS COMPUTATIONAL BIOLOGY, 7 (6), ARTN e.

Lewis, RA, Shahi, SK, Laing, E, Bucca, G, Efthimiou, G, Bushell, M and Smith, CP (2011) Genome-wide transcriptomic analysis of the response to nitrogen limitation in Streptomyces coelicolor A3(2). BMC Res Notes, 4.

Lewis, RA, Laing, E, Allenby, N, Bucca, G, Brenner, V, Harrison, M, Kierzek, AM and Smith, CP (2010) Metabolic and evolutionary insights into the closely-related species Streptomyces coelicolor and Streptomyces lividans deduced from high-resolution comparative genomic hybridization. BMC Genomics, 11.

Laing, E and Smith, CP (2010) RankProdIt: A web-interactive Rank Products analysis tool. BMC Res Notes, 3.

Salerno, P, Larsson, J, Bucca, G, Laing, E, Smith, CP and Flardh, K (2009) One of the Two Genes Encoding Nucleoid-Associated HU Proteins in Streptomyces coelicolor Is Developmentally Regulated and Specifically Involved in Spore Maturation J BACTERIOL, 191 (21). pp. 6489-6500.

Sooriakumaran, P, Macanas-Pirard, P, Bucca, G, Henderson, A, Langley, SE, Laing, RW, Smith, CP, Laing, EE and Coley, HM (2009) A gene expression profiling approach assessing celecoxib in a randomized controlled trial in prostate cancer. Cancer Genomics Proteomics, 6 (2). pp. 93-99.

Bucca, G, Laing, E, Mersinias, V, Allenby, N, Hurd, D, Holdstock, J, Brenner, V, Harrison, M and Smith, CP (2009) Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: characterization of the HspR regulon GENOME BIOLOGY, 10 (1), ARTN R.

Bucca, G, Laing, E, Mersinias, V, Allenby, N, Hurd, D, Holdstock, J, Brenner, V, Harrison, M and Smith, CP (2009) Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: characterization of the HspR regulon GENOME BIOL, 10 (1), R5.

Laing, E, Sidhu, K and Hubbard, SJ (2008) Predicted transcription factor binding sites as predictors of operons in Escherichia coli and Streptomyces coelicolor BMC GENOMICS, 9, 79.

Laing, E, Sidhu, K and Hubbard, SJ (2008) Predicted transcription factor binding sites as predictors of operons in Escherichia coli and Streptomyces coelicolor BMC GENOMICS, 9, ARTN 7.

Hesketh, A, Bucca, G, Laing, E, Flett, F, Hotchkiss, G, Smith, CP and Chater, KF (2007) New pleiotropic effects of eliminating a rare tRNA from Streptomyces coelicolor, revealed by combined proteomic and transcriptomic analysis of liquid cultures BMC GENOMICS, 8, 261.

Hesketh, A, Bucca, G, Laing, E, Flett, F, Hotchkiss, G, Smith, CP and Chater, KF (2007) New pleiotropic effects of eliminating a rare tRNA from Streptomyces coelicolor, revealed by combined proteomic and transcriptomic analysis of liquid cultures BMC GENOMICS, 8, ARTN 2.

Noens, EE, Mersinias, V, Willemse, J, Traag, BA, Laing, E, Chater, KF, Smith, CP, Koerten, HK and van Wezel, GP (2007) Loss of the controlled localization of growth stage-specific cell-wall synthesis pleiotropically affects developmental gene expression in an ssgA mutant of Streptomyces coelicolor MOLECULAR MICROBIOLOGY, 64 (5). pp. 1244-1259.

Beste, DJV, Laing, E, Bonde, B, Avignone-Rossa, C, Bushell, ME and McFadden, JJ (2007) Transcriptomic analysis identifies growth rate modulation as a component of the adaptation of mycobacteria to survival inside the macrophage JOURNAL OF BACTERIOLOGY, 189 (11). pp. 3969-3976.

Beste, DJV, Laing, E, Bonde, B, Avignone-Rossa, C, Bushell, ME and McFadden, JJ (2007) Transcriptomic analysis identifies growth rate modulation as a component of the adaptation of mycobacteria to survival inside the macrophage J BACTERIOL, 189 (11). pp. 3969-3976.

Tellez, JO, Dobrzynski, H, Greener, ID, Graham, GM, Laing, E, Honjo, H, Hubbard, SJ, Boyett, MR and Billeter, R (2006) Differential expression of ion channel transcripts in atrial muscle and sinoatrial node in rabbit CIRCULATION RESEARCH, 99 (12). pp. 1384-1393.

Laing, E, Mersinias, V, Smith, CP and Hubbard, SJ (2006) Analysis of gene expression in operons of Streptomyces coelicolor GENOME BIOLOGY, 7 (6), ARTN R.

Book Section

Thomas, SA, jin, Y, Laing, E and Smith, CP (2016) Modeling Dynamic Gene Expression in Streptomyces Coelicolor: Comparing Single and Multi-Objective Setups In: Evolutionary Computation in Gene Regulatory Network Research. John Wiley & Sons. ISBN 1118911512

Conference or Workshop Item

Archer, SN, Laing, EE, Moller-Levet, CS, van der Veen, DR, Bucca, G, Lazar, AS, Lo, JCY, Santhi, N, Slak, A, Kabiljo, R, von Schantz, M, Smith, CP and Dijk, DJ (2014) Mistimed sleep disrupts the circadian regulation of the human transcriptome In: 22nd Congress of the European-Sleep-Research-Society, 2014-09-16 - 2014-09-20, Tallinn, ESTONIA.

Lordan, J, Karanjia, N, Bucca, G, Laing, E and Smith, C (2010) Prospective analysis of the gene expression signature of peri-metastasis 'halo' tissue following neo-adjuvant chemotherapy-induced tumour reduction of colorectal liver metastasis In: Electronic Poster of Distinction in Association-of-Surgeons-of-Great-Britain-and-Ireland-International-Surgical-Congress, 2010-04-14 - 2010-04-16, Liverpool, ENGLAND.

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