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Ioannides, C and Konsue, N (2015) A principal mechanism for the cancer chemopreventive activity of phenethyl isothiocyanate is modulation of carcinogen metabolism DRUG METABOLISM REVIEWS, 47 (3). pp. 356-373.

Abdull Razis, AF, Konsue, N and Ioannides, C (2015) Inhibitory effect of phenethyl isothiocyanate against benzo[a] pyrene-induced rise in CYP1A1 mRNA and apoprotein levels as its chemopreventive properties. Asian Pac J Cancer Prev, 16 (7). pp. 2679-2683.

Papagiannidou, E, Skene, DJ and Ioannides, C (2014) Potential drug interactions with melatonin PHYSIOLOGY & BEHAVIOR, 131. pp. 17-24.

Di Bello, MG, Masini, E, Ioannides, C, Ndisang, JF, Raspanti, S, Bani Sacchi, T and Mannaioni, PF (2013) Erratum: Histamine release from rat mast cells induced by the metabolic activation of drugs of abuse into free radicals (Inflammation Research (1998) 47 (122-130) DOI 10.1007/s000110050299) Inflammation Research, 62 (2).

Lake, BG, Vickers, AEM and Ioannides, C (2013) Preface Xenobiotica, 43 (1).

Lake, BG, Dorne, JL and Ioannides, C (2012) David francis victor lewis (1949-2012). Xenobiotica, 42 (8).

Abdull Razis, AF, De Nicola, GR, Pagnotta, E, Iori, R and Ioannides, C (2012) Erratum to: A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase. Eur J Nutr.

Ioannides, C (2012) Up-regulation of cytochrome P450 and phase II enzymes by xenobiotics in precision-cut tissue slices. Xenobiotica.

Abdull Razis, AF, De Nicola, GR, Pagnotta, E, Iori, R and Ioannides, C (2012) A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase. Eur J Nutr.

Abdull Razis, AF, Bagatta, M, De Nicola, GR, Iori, R, Plant, N and Ioannides, C (2012) Characterization of the Temporal Induction of Hepatic Xenobiotic-Metabolizing Enzymes by Glucosinolates and Isothiocyanates: Requirement for at Least a 6 h Exposure To Elicit Complete Induction Profile. J Agric Food Chem, 60 (22). pp. 5556-5564.

Abdull Razis, AF, Hanlon, N, Soltys, E, Krizova, V, Iori, R, Plant, KE, Plant, N and Ioannides, C (2012) The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor. Archives of Toxicology, 86 (10). pp. 1505-1514.

Abdull Razis, AF, Konsue, N, Dervetzoglou, M, Plant, KE, Plant, N and Ioannides, C (2011) Phenethyl isothiocyanate, a naturally occurring phytochemical, is an antagonist of the aryl hydrocarbon receptor. Mol Nutr Food Res.

Khan, J, Jalal, JA, Ioannides, C and Moselhy, SS (2011) Impact of aqueous doash extract on urinary mutagenicity in rats exposed to heterocyclic amines. Toxicol Ind Health.

Cooke, BR, Bligh, SW, Cybulski, ZR, Ioannides, C and Hall, M (2011) Debrisoquine Metabolism and CYP2D Expression in Marmoset Liver Microsomes. Drug Metab Dispos.

Abdull Razis, AF, De Nicola, GR, Pagnotta, E, Iori, R and Ioannides, C (2011) 4-Methylsulfanyl-3-butenyl isothiocyanate derived from glucoraphasatin is a potent inducer of rat hepatic phase II enzymes and a potential chemopreventive agent. Arch Toxicol.

Abdull Razis, AF, Bagatta, M, De Nicola, GR, Iori, R and Ioannides, C (2011) Induction of epoxide hydrolase and glucuronosyl transferase by isothiocyanates and intact glucosinolates in precision-cut rat liver slices: importance of side-chain substituent and chirality. Arch Toxicol, 85 (8). pp. 919-927.

Razis, AFA, Iori, R and Ioannides, C (2011) The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer INTERNATIONAL JOURNAL OF CANCER, 128 (12). pp. 2775-2782.

Razis, AFA, Bagatta, M, De Nicola, GR, Iori, R and Ioannides, C (2011) Up-regulation of cytochrome P450 and phase II enzyme systems in rat precision-cut rat lung slices by the intact glucosinolates, glucoraphanin and glucoerucin LUNG CANCER, 71 (3). pp. 298-305.

Hanlon, N, Konsue, N, Coldham, N, Sauer, MJ and Ioannides, C (2011) Exposure to Isothiocyanates Suppresses Urinary Mutagenicity in Rats Treated With Heterocyclic Amine IQ: Lack of Association With CYP1 Activity NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 63 (2), PII 93. pp. 300-305.

Konsue, N and Ioannides, C (2010) Differential response of four human livers to modulation of phase II enzyme systems by the chemopreventive phytochemical phenethyl isothiocyanate MOLECULAR NUTRITION & FOOD RESEARCH, 54 (10). pp. 1477-1485.

Konsue, N and Ioannides, C (2010) Phenethyl isocyanate is not the metabolite of phenethyl isothiocyanate responsible for mechanism-based inhibition of cytochrome P450 ARCHIVES OF TOXICOLOGY, 84 (10). pp. 751-759.

Razis, AFA, Bagatta, M, De Nicola, GR, Iori, R and Ioannides, C (2010) Intact Glucosinolates Modulate Hepatic Cytochrome P450 and Phase II Conjugation Activities and can Contribute Directly to the Chemopreventive Activity of Cruciferous Vegetables DRUG METABOLISM REVIEWS, 42. p. 135.

Konsue, N, Kirkpatrick, J, Kuhnert, N, King, LJ and Ioannides, C (2010) Repeated oral administration modulates the pharmacokinetic behavior of the chemopreventive agent phenethyl isothiocyanate in rats MOLECULAR NUTRITION & FOOD RESEARCH, 54 (3). pp. 426-432.

Konsue, N and Ioannides, C (2010) Modulation of carcinogen-metabolising cytochromes P450 in human liver by the chemopreventive phytochemical phenethyl isothiocyanate, a constituent of cruciferous vegetables TOXICOLOGY, 268 (3). pp. 184-190.

Abdull Razis, AF, Bagatta, M, De Nicola, GR, Iori, R and Ioannides, C (2010) Intact glucosinolates modulate hepatic cytochrome P450 and phase II conjugation activities and may contribute directly to the chemopreventive activity of cruciferous vegetables Toxicology, 277 (1-3). pp. 74-85.

Hanlon, N, Coldham, N, Gielbert, A, Sauer, MJ and Ioannides, C (2009) Repeated intake of broccoli does not lead to higher plasma levels of sulforaphane in human volunteers CANCER LETTERS, 284 (1). pp. 15-20.

Hanlon, N, Poynton, CL, Coldham, N, Sauer, MJ and Ioannides, C (2009) The aliphatic isothiocyanates erucin and sulforaphane do not effectively up-regulate NAD(P)H:quinone oxidoreductase (NQO1) in human liver compared with rat MOLECULAR NUTRITION & FOOD RESEARCH, 53 (7). pp. 836-844.

Lopez-Mendez, C, Bermudez-Fajardo, A, Ioannides, C and Oviedo-Orta, E (2009) Effect of 2-amino-9H-pyrido[2,3-b]indole (A alpha C), a carcinogenic heterocyclic amine present in food, on atherosclerotic plaque development in apoE deficient mice TOXICOLOGY LETTERS, 185 (2). pp. 73-78.

Hanlon, N, Coldham, N, Sauer, MJ and Ioannides, C (2009) Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and sulforaphane CHEMICO-BIOLOGICAL INTERACTIONS, 177 (2). pp. 115-120.

Ioannides, C and Plant, NJ (2009) Professor George Gordon Gibson (1949-2008) XENOBIOTICA, 39 (8). p. 557.

Konsue, N and Ioannides, C (2008) Tissue differences in the modulation of rat cytochromes P450 and phase II conjugation systems by dietary doses of phenethyl isothiocyanate FOOD AND CHEMICAL TOXICOLOGY, 46 (12). pp. 3677-3683.

Staal, YCM, Pushparajah, DS, van Herwijnen, MHM, Gottschalk, RWH, Maas, LM, Ioannides, C, van Schooten, FJ and van Delft, JHM (2008) Interactions between polycyclic aromatic hydrocarbons in binary mixtures: Effects on gene expression and DNA adduct formation in precision-cut rat liver slices MUTAGENESIS, 23 (6). pp. 491-499.

Hanlon, N, Coldham, N, Sauer, MJ and Ioannides, C (2008) Up-regulation of the CYP1 family in rat and human liver by the aliphatic isothiocyanates erucin and sulforaphane TOXICOLOGY, 252 (1-3). pp. 92-98.

Hanlon, N, Okpara, A, Coldham, N, Sauer, MJ and Ioannides, C (2008) Modulation of rat hepatic and pulmonary cytochromes P450 and phase II enzyme systems by erucin, an lsothiocyanate structurally related to sulforaphane JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 56 (17). pp. 7866-7871.

Pushparajah, DS, Umachandran, M, Plant, KE, Plant, N and Ioannides, C (2008) Up-regulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung MUTAGENESIS, 23 (4). pp. 299-308.

Bermudez-Fajardo, A, Lopez-Mendez, C, Ioannides, C and Oviedo-Orta, E (2008) EFFECT OF 2-AMINO-9H-PYRIDO [2,3-B] INDOLE (AAC) ON ATHEROSCLEROTIC PLAQUE DEVELOPMENT IN APOE DEFICIENT MICE ATHEROSCLEROSIS SUPP, 9 (1). p. 45.

Pushparajah, DS, Umachandran, M, Plant, KE, Plant, N and Ioannides, C (2008) Differential response of human and rat epoxide hydrolase to polycyclic aromatic hydrocarbon exposure: Studies using precision-cut tissue slices MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 640 (1-2). pp. 153-161.

Hanlon, N, Coldham, N, Gielbert, A, Kuhnert, N, Sauer, MJ, Kingi, LJ and Ioannides, C (2008) Absolute bioavailability and dose-dependent pharmacokinetic behaviour of dietary doses of the chemopreventive isothiocyanate sulforaphane in rat BRITISH JOURNAL OF NUTRITION, 99 (3). pp. 559-564.

Pushparajah, DS, Umachandran, M, Nazir, T, Plant, KE, Plant, N, Lewis, DFV and Ioannides, C (2008) Up-regulation of CYP1A/B in rat lung and liver, and human liver precision-cut slices by a series of polycyclic aromatic hydrocarbons; association with the Ah locus and importance of molecular size TOXICOLOGY IN VITRO, 22 (1). pp. 128-145.

Pushparajah, DS, Umachandran, M, Plant, KE, Plant, N and Ioannides, C (2007) Evaluation of the precision-cut liver and lung slice systems for the study of induction of CYP1, epoxide hydrolase and glutathione S-transferase activities TOXICOLOGY, 231 (1). pp. 68-80.

Staal, YCM, van Herwijnen, MHM, Pushparajah, DS, Umachandran, M, Ioannides, C, van Schooten, FJ and van Delft, JHM (2007) Modulation of gene expression and DNA-adduct formation in precision-cut liver slices exposed to polycyclic aromatic hydrocarbons of different carcinogenic potency MUTAGENESIS, 22 (1). pp. 55-62.

Umachandran, M and Ioannides, C (2006) Stability of cytochromes P450 and phase II conjugation systems in precision-cut rat lung slices cultured up to 72h TOXICOLOGY, 224 (1-2). pp. 14-21.

Skene, DJ, Timbers, SE, Middleton, B, English, J, Kopp, C, Tobler, I and Ioannides, C (2006) Mice convert melatonin to 6-sulphatoxymelatonin GENERAL AND COMPARATIVE ENDOCRINOLOGY, 147 (3). pp. 371-376.

Ioannides, C (2006) Cytochrome P450 expression in the liver of food-producing animals CURRENT DRUG METABOLISM, 7 (4). pp. 335-348.

Yoxall, V, Kentish, P, Coldham, N, Kuhnert, N, Sauer, MJ and Ioannides, C (2005) Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity INTERNATIONAL JOURNAL OF CANCER, 117 (3). pp. 356-362.

Yoxall, V, Umachandran, M, Wilson, J, Kentish, P and Ioannides, C (2005) Black tea intake modulates the excretion of urinary mutagens in rats exposed to 6-aminochrysene: induction of cytochromes P450 by 6-aminochrysene in the rat MUTAGENESIS, 20 (1). pp. 23-28.

Yoxall, VR, Bishop, J and Ioannides, C (2004) Effect of black tea intake on the excretion of mutagens in the urine of volunteers taking a beef meal CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 13 (12). pp. 2196-2202.

Umachandran, M, Howarth, J and Ioannides, C (2004) Metabolic and structural viability of precision-cut rat lung slices in culture XENOBIOTICA, 34 (8). pp. 771-780.

Yoxall, VR, Parker, DA, Kentish, PA and Ioannides, C (2004) Short-term black tea intake modulates the excretion of urinary mutagens in rats treated with 2-amino-3-methylimidazo-[4,5-f]quinoline (IQ): role of CYP1A2 upregulation ARCHIVES OF TOXICOLOGY, 78 (8). pp. 477-482.

Yoxall, V, Wilson, J and Ioannides, C (2004) An improved method for the extraction of mutagens from human urine and cooked meat using blue rayon MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 559 (1-2). pp. 121-130.

Sivapathasundaram, S, Howells, LC, Sauer, MJ and Ioannides, C (2004) Functional integrity of precision-cut liver slices from deer and cattle JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 27 (2). pp. 79-84.

Ioannides, C and Lewis, DFV (2004) Cytochromes P450 in the bioactivation of chemicals CURRENT TOPICS IN MEDICINAL CHEMISTRY, 4 (16). pp. 1767-1788.

Ioannides, C and Yoxall, V (2003) Antimutagenic activity of tea: role of polyphenols CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 6 (6). pp. 649-656.

Catterall, F, Kassimi, AI, Clifford, MN and Ioannides, C (2003) Influence of milk on the antimutagenic potential of green and black teas ANTICANCER RESEARCH, 23 (5A). pp. 3863-3867.

Catterall, F, McArdle, NJ, Mitchell, L, Papayanni, A, Clifford, MN and Ioannides, C (2003) Hepatic and intestinal cytochrome P450 and conjugase activities in rats treated with black tea theafulvins and theaflavins FOOD AND CHEMICAL TOXICOLOGY, 41 (8). pp. 1141-1147.

Catterall, F, King, LJ, Clifford, MN and Ioannides, C (2003) Bioavailability of dietary doses of H-3-labelled tea antioxidants (+)-catechin and (-)-epicatechin in rat XENOBIOTICA, 33 (7). pp. 743-753.

Sivapathasundaram, S, Magnisali, P, Coldham, NG, Howells, LC, Sauer, MJ and Ioannides, C (2003) Cytochrome P450 expression and testosterone metabolism in the liver of deer TOXICOLOGY, 187 (1). pp. 49-65.

Catterall, F, Copeland, E, Clifford, MN and Ioannides, C (2003) Effects of black tea theafulvins on aflatoxin B-1 mutagenesis in the Ames test MUTAGENESIS, 18 (2). pp. 145-150.

Ioannides, C (2003) Dennis Vernon William Parke, Ph.D., D.S.c, C.Chem., F.R.S.C, F.I.Biol., F.R.C.Path. (November 1922-november 2002) - In memoriam DRUG METABOLISM REVIEWS, 35 (1). V-VI.

Sivapathasundaram, S, Sauer, MJ and Ioannides, C (2003) Xenobiotic conjugation systems in deer compared with cattle and rat COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 134 (1), PII S1532-. pp. 169-173.

Lewis, DFV, Ioannides, C and Parke, DV (2003) A quantitative structure-activity relationship (QSAR) study of mutagenicity in several series of organic chemicals likely to be activated by cytochrome P450 enzymes TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS. pp. 187-193.

Ioannides, C (2003) Drug-phytochemical interactions. Inflammopharmacology, 11 (1). pp. 7-42.

Catterall, F, King, LJ and Ioannides, C (2002) Mutagenic activity of the glutathione S-transferase substrate 1-chloro-2,4-dinitrobenzene (CDNB) in the Salmonella mutagenicity assay MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 520 (1-2), PII S1383-. pp. 119-124.

Ioannides, C (2002) Topics in Xenobiochemistry - Pharmacokinetic interactions between herbal remedies and medicinal drugs XENOBIOTICA, 32 (6). pp. 451-478.

Ioannides, C (2002) Pharmacokinetic interactions between herbal remedies and medicinal drugs. Xenobiotica, 32 (6). pp. 451-478.

Dhawan, A, Anderson, D, de Pascual-Teresa, S, Santos-Buelga, C, Clifford, MN and Ioannides, C (2002) Evaluation of the antigenotoxic potential of monomeric and dimeric flavanols, and black tea polyphenols against heterocyclic amine-induced DNA damage in human lymphocytes using the Comet assay MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 515 (1-2), PII S1383-. pp. 39-56.

Skene, DJ, Papagiannidou, E, Hashemi, E, Snelling, J, Lewis, DFV, Fernandez, M and Ioannides, C (2001) Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices JOURNAL OF PINEAL RESEARCH, 31 (4). pp. 333-342.

Sivapathasundaram, S, Magnisali, P, Coldham, NG, Howells, LC, Sauer, MJ and Ioannides, C (2001) A study of the expression of the xenobiotic-metabolising cytochrome P450 proteins and of testosterone metabolism in bovine liver BIOCHEMICAL PHARMACOLOGY, 62 (5). pp. 635-645.

Ioannides, C (2001) Effect of phytochemicals on cytochrome P450 expression: Clinical implications. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 222. U47-U47.

Catterall, FS, Coombs, MM, Ioannides, C, Sepiol, JJ and Wilson, J (2001) Mutagenicity of bay-region amino-substituted cyclopenta[a]phenanthrenes and 2-and 5-aminochrysene MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 492 (1-2). pp. 7-11.

Walton, K, Coombs, MM, Walker, R and Ioannides, C (2001) The metabolism and bioactivation of agaritine and of other mushroom hydrazines by whole mushroom homogenate and by mushroom tyrosinase TOXICOLOGY, 161 (3). pp. 165-177.

Anderson, D, Dhawan, A, Yardley-Jones, A, Ioannides, C and Webb, J (2001) Effect of antioxidant flavonoids and a food mutagen on lymphocytes of a thalassemia patient without chelation therapy in the comet assay TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS, 21 (2). pp. 165-174.

Lewis, DFV, Ioannides, C, Parke, DV and Schulte-Hermann, R (2000) Quantitative structure-activity relationships in a series of endogenous and synthetic steroids exhibiting induction of CYP3A activity and hepatomegaly associated with increased DNA synthesis JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 74 (4). pp. 179-185.

Hashemi, E, Till, C and Ioannides, C (2000) Stability of cytochrome P450 proteins in cultured precision-cut rat liver slices TOXICOLOGY, 149 (2-3). pp. 51-61.

Catterall, FS, Coombs, MM, Ioannides, C and Walton, K (2000) Bioactivation of the carcinogen 11-methoxy-16,17-dihydro-15H-cyclopenta[a]phenanthrene MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 465 (1-2). pp. 85-90.

Catteral, F, Souquet, JM, Cheynier, V, de Pascual-Teresa, S, Santos-Buelga, C, Clifford, MN and Ioannides, C (2000) Differential modulation of the genotoxicity of food carcinogens by naturally occurring monomeric and dimeric polyphenolics ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 35 (2). pp. 86-98.

Walton, K, Coombs, MM, King, LJ, Walker, R and Ioannides, C (2000) Fate of the mushroom hydrazine agaritine in the rat and mouse NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 37 (1). pp. 55-64.

Catterall, F, Souquet, JM, Cheynier, V, Clifford, MN and Ioannides, C (2000) Modulation of the mutagenicity of food carcinogens by oligomeric and polymeric procyanidins isolated from grape seeds: synergistic genotoxicity with N-nitrosopyrrolidine JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 80 (1). pp. 91-101.

Barnett, CR and Ioannides, C (2000) Xenobiotic-metabolizing enzyme systems and aging. Methods Mol Med, 38. pp. 119-130.

Bu-Abbas, A, Dobrota, M, Copeland, E, Clifford, MN, Walker, R and Ioannides, C (1999) Proliferation of hepatic peroxisomes in rats following the intake of green or black tea TOXICOLOGY LETTERS, 109 (1-2). pp. 69-76.

Marczylo, T and Ioannides, C (1999) Evidence for the presence of a microsomal NADH-dependent enzyme system that can bioactivate aromatic amines in the liver of rats and mice TOXICOLOGY, 134 (2-3). pp. 127-141.

Hashemi, E, Till, C and Ioannides, C (1999) Stability of Phase II conjugation systems in cultured precision-cut rat hepatic slices TOXICOLOGY IN VITRO, 13 (3). pp. 459-466.

McArdle, NJ, Clifford, MN and Ioannides, C (1999) Consumption of tea modulates the urinary excretion of mutagens in rats treated with IQ. Role of caffeine MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 441 (2). pp. 191-203.

Bu-Abbas, A, Clifford, MN, Walker, R and Ioannides, C (1999) Modulation of hepatic cytochrome P450 activity and carcinogen bioactivation by black and decaffeinated black tea ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 7 (1). pp. 41-47.

Bu-Abbas, A, Clifford, MN, Walker, R and Ioannides, C (1999) Modulation of hepatic cytochrome P450 activity and carcinogen bioactivation by black and decaffeinated black tea. Environ Toxicol Pharmacol, 7 (1). pp. 41-47.

Ioannides, C (1999) Effect of diet and nutrition on the expression of cytochromes P450 XENOBIOTICA, 29 (2). pp. 109-154.

Blouin, RA, Farrell, GC, Ioannides, C, Renton, K and Watlington, CO (1999) Impact of diseases on detoxication JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 13 (3-4). 215-+.

Hashemi, E, Dobrota, M, Till, C and Ioannides, C (1999) Structural and functional integrity of precision-cut liver slices in xenobiotic metabolism: a comparison of the dynamic organ and multiwell plate culture procedures XENOBIOTICA, 29 (1). pp. 11-25.

Bu-Abbas, A, Clifford, MN, Walker, R and Ioannides, C (1998) Contribution of caffeine and flavanols in the induction of hepatic phase II activities by green tea (vol 36, pg 617, 1998) FOOD AND CHEMICAL TOXICOLOGY, 36 (12). I-I.

Bu-Abbas, A, Clifford, MN, Walker, R and Ioannides, C (1998) Erratum: Contribution of caffeine and flavanols in the induction of hepatic phase II activities by green tea (Food and Chemical Toxicology 36 (8) (617-621) (1998)) Food and Chemical Toxicology, 36 (12).

Catterall, F, Copeland, E, Clifford, MN and Ioannides, C (1998) Contribution of theafulvins to the antimutagenicity of black tea: their mechanism of action MUTAGENESIS, 13 (6). pp. 631-636.

Lewis, DFV, Ioannides, C and Parke, DV (1998) Cytochromes P450 and species differences in xenobiotic metabolism and activation of carcinogen ENVIRONMENTAL HEALTH PERSPECTIVES, 106 (10). pp. 633-641.

Lewis, DFV, Ioannides, C and Parke, DV (1998) A combined COMPACT and HazardExpert study of 40 chemicals for which information on mutagenicity and carcinogenicity is known, including the results of human epidemiological studies HUMAN & EXPERIMENTAL TOXICOLOGY, 17 (10). pp. 577-586.

Bu-Abbas, A, Clifford, MN, Walker, R and Ioannides, C (1998) Contribution of caffeine and flavanols in the induction of hepatic phase II activities by green tea FOOD AND CHEMICAL TOXICOLOGY, 36 (8). pp. 617-621.

Marczylo, T and Ioannides, C (1998) The substrate specificity of the rat hepatic cytosolic arylamine oxidase catalyzing the bioactivation of aromatic amines CANCER LETTERS, 127 (1-2). pp. 141-146.

Irizar, A and Ioannides, C (1998) Marked inhibition of hepatic cytochrome P450 activity in cholesterol-induced atherosclerosis in rabbits TOXICOLOGY, 126 (3). pp. 179-193.

Walton, K, Walker, R and Ioannides, C (1998) Effect of baking and freeze-drying on the direct and indirect mutagenicity of extracts from the edible mushroom Agaricus bisporus FOOD AND CHEMICAL TOXICOLOGY, 36 (4). pp. 315-320.

Di Bello, MG, Masini, E, Ioannides, C, Ndisang, JF, Raspanti, S, Sacchi, TB and Mannaioni, PF (1998) Histamine release from rat mast cells induced by the metabolic activation of drugs of abuse into free radicals INFLAMMATION RESEARCH, 47 (3). pp. 122-130.

Anderson, D, Yu, TW, Wright, J and Ioannides, C (1998) An examination of DNA strand breakage in the comet assay and antioxidant capacity in diabetic patients MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 398 (1-2). pp. 151-161.

Lewis, DFV, Ioannides, C and Parke, DV (1998) Further evaluation of COMPACT, the molecular orbital approach for the prospective safety evaluation of chemicals MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 412 (1). pp. 41-54.

Lewis, DFV, Ioannides, C and Parke, DV (1998) An improved and updated version of the compact procedure for the evaluation of P450-mediated chemical activation DRUG METABOLISM REVIEWS, 30 (4). pp. 709-737.

Ioannides, C (1997) Chapter 53 Activation mechanisms of chemical toxicity Principles of Medical Biology, 8 (C). pp. 1013-1032.

BuAbbas, A, Copeland, E, Clifford, MN, Walker, R and Ioannides, C (1997) Fractionation of green tea extracts: Correlation of antimutagenic effect with flavanol content JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 75 (4). pp. 453-462.

Walton, K, Coombs, MM, Walker, R and Ioannides, C (1997) Bioactivation of mushroom hydrazines to mutagenic products by mammalian and fungal enzymes MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, 381 (1). pp. 131-139.

Walton, K, Coombs, MM, Catterall, FS, Walker, R and Ioannides, C (1997) Bioactivation of the mushroom hydrazine, agaritine, to intermediates that bind covalently to proteins and induce mutations in the Ames test CARCINOGENESIS, 18 (8). pp. 1603-1608.

Marczylo, T and Ioannides, C (1997) Induction of the rat hepatic cytosolic arylamine oxidase by a series of polychlorinated biphenyls: Association with the Ah locus TOXICOLOGY LETTERS, 92 (2). pp. 81-91.

Cheung, YL, Lewis, DFV, Ridd, TI, Gray, TJB and Ioannides, C (1997) Diaminonaphthalenes and related aminocompounds: Mutagenicity, CYP1A induction and interaction with the Ah receptor TOXICOLOGY, 118 (2-3). pp. 115-127.

Lewis, DFV, Brantom, PG, Ioannides, C, Walker, R and Parke, DV (1997) Nitrosamine carcinogenesis: Rodent assays, quantitative structure-activity relationships, and human risk assessment DRUG METABOLISM REVIEWS, 29 (4). pp. 1055-1078.

Clarke, J, Snelling, J, Ioannides, C, Flatt, PR and Barnett, CR (1996) Effect of vitamin C supplementation on hepatic cytochrome P450 mixed-function oxidase activity in streptozotocin-diabetic rats TOXICOLOGY LETTERS, 89 (3). pp. 249-256.

BuAbbas, A, Nunez, X, Clifford, MN, Walker, R and Ioannides, C (1996) A comparison of the antimutagenic potential of green, black and decaffeinated teas: Contribution of flavanols to the antimutagenic effect MUTAGENESIS, 11 (6). pp. 597-603.

Lewis, DFV, Ioannides, C and Parke, DV (1996) COMPACT and molecular structure in toxicity assessment: A prospective evaluation of 30 chemicals currently being tested for rodent carcinogenicity by the NCI/NTP ENVIRONMENTAL HEALTH PERSPECTIVES, 104. pp. 1011-1016.

Patrineli, A, Clifford, MN and Ioannides, C (1996) Contribution of phenols, quinones and reactive oxygen species to the mutagenicity of white grape juice in the Ames test FOOD AND CHEMICAL TOXICOLOGY, 34 (9). pp. 869-872.

Cheung, YL, Snelling, J, Mohammed, NND, Gray, TJB and Ioannides, C (1996) Interaction with the aromatic hydrocarbon receptor, CYP1A induction, and mutagenicity of a series of diaminotoluenes: Implications for their carcinogenicity TOXICOLOGY AND APPLIED PHARMACOLOGY, 139 (1). pp. 203-211.

Patrineli, A, Clifford, MN, Walker, R and Ioannides, C (1996) Mutagenicity of white grape juice in the Ames test FOOD AND CHEMICAL TOXICOLOGY, 34 (6). pp. 559-562.

Machala, M, Nezveda, K, Irizar, A, Bu-Abbas, A and Ioannides, C (1996) Expression and inducibility of cytochrome P450 proteins in the liver of chick embryo. Arch Toxicol, 71 (1-2). pp. 57-63.

Bu-Abbas, A, Clifford, MN, Ioannides, C and Walker, R (1995) Stimulation of rat hepatic UDP-glucuronosyl transferase activity following treatment with green tea. Food Chem Toxicol, 33 (1). pp. 27-30.

Ioannides, C and Parke, DV (1994) Erratum: Induction of cytochrome P4501 as an indicator of potential chemical carcinogenesis (Drug Metabolism Reviews, Volume 25, Number 4) Drug Metabolism Reviews, 26 (1-2).

Ioannides, C and Parke, DV (1993) Glutathione. Xenobiotica, 23 (8). pp. 821-822.

Ioannides, C, Lewis, DF and Parke, DV (1993) Computer modelling in predicting carcinogenicity. Eur J Cancer Prev, 2 (3). pp. 275-282.

Ioannides, C and Parke, DV (1993) Editorial Xenobiotica, 23 (8). pp. 821-822.

Cheung, YL, Gray, TJB and Ioannides, C (1992) Interaction of chyrsene and methylchrysenes with cytochrome P450 and its relationship to their carcinogenic potential Human and Experimental Toxicology, 11 (6).

Powell, CJ and Ioannides, C (1992) Nephrotoxicity is closely correlated with mutagenicity for a series of analogues of 2-bromoethanamine, suggesting a mechanistic relationship Human and Experimental Toxicology, 11 (6). pp. 588-589.

Parke, AL, Ioannides, C, Lewis, DFV and Parke, DV (1991) Molecular pathology of drug-disease interactions in chronic autoimmune inflammatory diseases Inflammopharmacology, 1 (1). pp. 3-36.

Barnett, CR, Flatt, PR and Ioannides, C (1990) Induction of hepatic microsomal P450 I and IIB proteins by hyperketonaemia. Biochem Pharmacol, 40 (2). pp. 393-397.

Parke, DV, Ioannides, C, Lewis, DF and Obrebska-Parke, MJ (1990) Current problems in the evaluation of chemical safety. Pol J Occup Med, 3 (1). pp. 15-41.

Ioannides, C (1989) Metabolic activation of chemical carcinogens: The polycyclic aromatic hydrocarbons Review of Clinical Pharmacology and Pharmacokinetics, International Edition, 3 (2). pp. 115-122.

Ioannides, C, Lewis, DF, Trinick, J, Neville, S, Sertkaya, NN, Kajbaf, M and Gorrod, JW (1989) A rationale for the non-mutagenicity of 2- and 3-aminobiphenyls. Carcinogenesis, 10 (8). pp. 1403-1407.

Hayes, PC, Jenkins, D, Vavianos, P, Dagap, K, Johnston, A, Ioannides, C, Thomas, P and Williams, R (1987) Single oral dose pharmacokinetics of bisoprolol 10 mg in liver disease. Eur Heart J, 8 Supp. pp. 23-29.

Payton, CD, Fox, JG, Pauleau, NF, Boulton-Jones, JM, Ioannides, C, Johnston, A and Thomas, P (1987) The single dose pharmacokinetics of bisoprolol (10 mg) in renal insufficiency: the clinical significance of balanced clearance. Eur Heart J, 8 Supp. pp. 15-22.

Lewis, DF, Ioannides, C and Parke, DV (1987) Structural requirements for substrates of cytochromes P-450 and P-448. Chem Biol Interact, 64 (1-2). pp. 39-60.

Gibson, GG, Tamburini, PP, Masson, H and Ioannides, C (1982) Multiple forms of hepatic cytochrome P-450: Catalytic activity of a highly purified haemoprotein induced by clofibrate pretreatment in the rat Biochemical Society Transactions, 10 (6). pp. 447-448.

Delaforge, M, Ioannides, C and Parke, DV (1980) Ligand binding of safrole to cytochrome P-450. Arch Toxicol Suppl, 4. pp. 45-48.

Ioannides, C, Okine, L and Parke, DV (1979) Effects of β-adrenoceptor antagonists on the hepatic mixed-function oxygenases in the rat British Journal of Pharmacology, 67 (3).

Ioannides, C, Okine, L and Parke, DV (1979) Effects of beta-adrenoceptor antagonists on the hepatic mixed-function oxygenases in the rat [proceedings]. Br J Pharmacol, 67 (3). 451P-452P.

Tong, S, Ioannides, C and Parke, DV (1977) Enhancement of 2-hydroxylation in vitro of biphenyl by organochlorine insecticides [proceedings]. Biochem Soc Trans, 5 (5). pp. 1374-1377.

Tong, S, Ioannides, C and Parke, DV (1977) Possible pitfalls of the biphenyl test for chemical carcinogens [proceedings]. Biochem Soc Trans, 5 (5). pp. 1372-1374.

Ioannides, C, Chakraborty, J and Parke, DV (1974) Improvement of barbiturate gas chromatography by formic acid: Possible mechanism Chromatographia, 7 (7). pp. 351-356.

Ioannides, C and Parke, DV (1973) The effect of ethanol administration on drug oxidations and possible mechanism of ethanol barbiturate interactions Biochemical Society Transactions, 1 (3). pp. 716-720.

Conference or Workshop Item

Ioannides, C and Konsue, N (2008) Effect of phenethyl isothiocyanate (PEITC) on the urinary excretion of mutagens in rats treated with IQ (2-amino-3-methyl-3H-imidazo[4,5-f] quinoline) In: 45th Congress of the European-Societies-of-Toxicology, 2008-10-05 - 2008-10-08, Rhodes, GREECE.

Ioannides, C and Konsue, N (2008) Influence of phenethyl isothiocyanate (PEITC) on carcinogen-metabolising enzymes in human liver: Studies with precision-cut slices In: 45th Congress of the European-Societies-of-Toxicology, 2008-10-05 - 2008-10-08, Rhodes, GREECE.

Ioannides, C and Konsue, N (2008) Modulation of carcinogen-metabolising enzyme systems in the liver and lung of rats treated with dietary doses of phenethyl isothiocyanate (PEITC) In: 45th Congress of the European-Societies-of-Toxicology, 2008-10-05 - 2008-10-08, Rhodes, GREECE.

Konsue, N and Ioannides, C (2007) Chemoprevention effect of phenethyl isothiocyanate In: Annual Congress of the British-Toxicological-Society, 2007-04-15 - 2007-04-18, Univ Surrey, Guildford, ENGLAND.

Umachandran, M and Ioannides, C (2007) Interactions between polycyclic aromatic hydrocarbons in precision-cut rat lung slices In: Annual Congress of the British-Toxicological-Society, 2007-04-15 - 2007-04-18, Univ Surrey, Guildford, ENGLAND.

Arya, N, Ioannides, C, Kuhnert, N, Kirkpatrick, J and Stevenson, D (2007) Metabolism of 2-amino-3-methylimidazol [4,5,f]quinoline by precision-cut rat liver slices In: Annual Congress of the British-Toxicological-Society, 2007-04-15 - 2007-04-18, Univ Surrey, Guildford, ENGLAND.

Efferson, C, Kawano, K, Sellappan, S, Yu, DH, Babaian, R, Palese, P, Garcia-Sastre, A, Ioannides, C and Murray, J (2004) Prostate tumor cells infected with a recombinant influenza virus with truncated NS1 gene NS1 (1-126) activate cytolytic CD8+ cells which recognize non-infected tumors In: 19th Annual Scientific Meeting of the International-Society-for-Biological-Therapy-of-Cancer, 2004-11-04 - 2004-11-07, San Francisco, CA.

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