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Morgan, R, Simpson, G, Gray, S, Gillett, C, Tabi, Z, Spicer, J, Harrington, KJ and Pandha, HS (2016) HOX transcription factors are potential targets and markers in malignant mesothelioma BMC CANCER, 16, ARTN 85.

Relph, KL, Pandha, H, Simpson, GR, Melcher, A and Harrington, K (2016) Cancer immunotherapy via combining oncolytic virotherapy with chemotherapy: recent advances Oncolytic Virotherapy, 2016 (5). pp. 1-13.

Rajani, K, Parrish, C, Kottke, T, Thompson, J, Zaidi, S, Ilett, L, Shim, KG, Diaz, R-M, Pandha, H, Harrington, K, Coffey, M, Melcher, A and Vile, R (2016) Combination Therapy With Reovirus and Anti-PD-1 Blockade Controls Tumor Growth Through Innate and Adaptive Immune Responses MOLECULAR THERAPY, 24 (1). pp. 166-174.

Blanchard, M, Shim, KG, Grams, MP, Rajani, K, Diaz, RM, Furutani, KM, Thompson, J, Olivier, KR, Park, SS, Markovic, SN, Pandha, H, Melcher, A, Harrington, K, Zaidi, S and Vile, R (2015) Definitive Management of Oligometastatic Melanoma in a Murine Model Using Combined Ablative Radiation Therapy and Viral Immunotherapy INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 93 (3). pp. 577-587.

Roulstone, V, Pedersen, M, Kyula, J, Mansfield, D, Khan, AA, McEntee, G, Wilkinson, M, Karapanagiotou, E, Coffey, M, Marais, R, Jebar, A, Errington-Mais, F, Melcher, A, Vile, R, Pandha, H, McLaughlin, M and Harrington, KJ (2015) BRAF- and MEK-Targeted Small Molecule Inhibitors Exert Enhanced Antimelanoma Effects in Combination With Oncolytic Reovirus Through ER Stress MOLECULAR THERAPY, 23 (5). pp. 931-942.

Zaidi, S, Blanchard, M, Shim, K, Ilett, E, Rajani, K, Parrish, C, Boisgerault, N, Kottke, T, Thompson, J, Celis, E, Pulido, J, Selby, P, Pandha, H, Melcher, A, Harrington, K and Vile, R (2015) Mutated BRAF Emerges as a Major Effector of Recurrence in a Murine melanoma Model After Treatment With Immunomodulatory Agents MOLECULAR THERAPY, 23 (5). pp. 845-856.

Roulstone, V, Khan, K, Pandha, HS, Rudman, S, Coffey, M, Gill, GM, Melcher, AA, Vile, R, Harrington, KJ, de Bono, J and Spicer, J (2015) Phase I Trial of Cyclophosphamide as an Immune Modulator for Optimizing Oncolytic Reovirus Delivery to Solid Tumors CLINICAL CANCER RESEARCH, 21 (6). pp. 1305-1312.

Seth, R, Khan, AA, Pencavel, TD, Wilkinson, MJ, Kyula, JN, Simpson, G, Pandha, H, Melcher, A, Vile, R, Harris, PA and Harrington, KJ (2015) Adenovirally Delivered Enzyme Prodrug Therapy with Herpes Simplex Virus-Thymidine Kinase in Composite Tissue Free Flaps Shows Therapeutic Efficacy in Rat Models of Glioma PLASTIC AND RECONSTRUCTIVE SURGERY, 135 (2). pp. 475-487.

Appleton, ES, Turnbull, S, Ralph, C, West, E, Scott, K, Harrington, K, Pandha, H and Melcher, A (2015) Talimogene laherparepvec in the treatment of melanoma EXPERT OPINION ON BIOLOGICAL THERAPY, 15 (10). pp. 1517-1530.

Alonso-Camino, V, Rajani, K, Kottke, T, Rommelfanger-Konkol, D, Zaidi, S, Thompson, J, Pulido, J, Ilett, E, Donnelly, O, Selby, P, Pandha, H, Melcher, A, Harrington, K, Diaz, RM and Vile, R (2014) The Profile of Tumor Antigens Which Can be Targeted by Immunotherapy Depends Upon the Tumor's Anatomical Site MOLECULAR THERAPY, 22 (11). pp. 1936-1948.

Ilett, E, Kottke, T, Donnelly, O, Thompson, J, Willmon, C, Diaz, R, Zaidi, S, Coffey, M, Selby, P, Harrington, K, Pandha, H, Melcher, A and Vile, R (2014) Cytokine Conditioning Enhances Systemic Delivery and Therapy of an Oncolytic Virus MOLECULAR THERAPY, 22 (10). pp. 1851-1863.

Morgan, R, Gray, S, Gillett, C, Tabi, Z, Launchbury, F, Spicer, J, Harrington, K and Pandha, HS (2014) HOX TRANSCRIPTION FACTORS ARE POTENTIAL TARGETS AND MARKERS IN MALIGNANT MESOTHELIOMA ANTICANCER RESEARCH, 34 (10). pp. 6069-6071.

Kyula, JN, Khan, AA, Mansfield, D, Karapanagiotou, EM, Mclaughlin, M, Roulstone, V, Zaidi, S, Pencavel, T, Touchefeu, Y, Seth, R, Chen, NG, Yu, YA, Zhang, Q, Melcher, AA, Vile, RG, Pandha, HS, Ajaz, M, Szalay, AA and Harrington, KJ (2014) Synergistic cytotoxicity of radiation and oncolytic Lister strain vaccinia in V600D/EBRAF mutant melanoma depends on JNK and TNF-α signaling Oncogene, 33 (13). pp. 1700-1712.

Jennings, VA, Ilett, EJ, Scott, KJ, West, EJ, Vile, R, Pandha, H, Harrington, K, Young, A, Hall, GD, Coffey, M, Selby, P, Errington-Mais, F and Melcher, AA (2014) Lymphokine-activated killer and dendritic cell carriage enhances oncolytic reovirus therapy for ovarian cancer by overcoming antibody neutralization in ascites INTERNATIONAL JOURNAL OF CANCER, 134 (5). pp. 1091-1101.

Morgan, R, Boxall, A, Harrington, KJ, Simpson, GR, Michael, A and Pandha, HS (2014) Targeting HOX transcription factors in prostate cancer BMC UROLOGY, 14, ARTN 1.

Kottke, T, Boisgerault, N, Diaz, RM, Donnelly, O, Rommelfanger-Konkol, D, Pulido, J, Thompson, J, Mukhopadhyay, D, Kaspar, R, Coffey, M, Pandha, H, Melcher, A, Harrington, K, Selby, P and Vile, R (2013) Detecting and targeting tumor relapse by its resistance to innate effectors at early recurrence NATURE MEDICINE, 19 (12). pp. 1625-1631.

Boisgerault, N, Kottke, T, Pulido, J, Thompson, J, Diaz, RM, Rommelfanger-Konkol, D, Embry, A, Saenz, D, Poeschla, E, Pandha, H, Harrington, K, Melcher, A, Selby, P and Vile, R (2013) Functional Cloning of Recurrence-specific Antigens Identifies Molecular Targets to Treat Tumor Relapse MOLECULAR THERAPY, 21 (8). pp. 1507-1516.

Donnelly, O, Harrington, K, Melcher, A and Pandha, H (2013) Live viruses to treat cancer JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, 106 (8). pp. 310-314.

Comins, C, Simpson, GR, Relph, K, Harrington, KJ, Melcher, A and Pandha, H (2013) Reoviral Therapy for Cancer: Strategies for Improving Antitumor Efficacy Using Radio- and Chemotherapy pp. 185-198.

Adair, RA, Scott, KJ, Fraser, S, Errington-Mais, F, Pandha, H, Coffey, M, Selby, P, Cook, GP, Vile, R, Harrington, KJ, Toogood, G and Melcher, AA (2012) Cytotoxic and immune-mediated killing of human colorectal cancer by reovirus-loaded blood and liver mononuclear cells. Int J Cancer.

Morgan, Richard, Boxall, A, Simpson, Guy, Michael, Agnieszka, Pandha, Hardev, Harrington, KJ and Gillett, C (2012) Targeting the HOX/PBX dimer in breast cancer Breast Cancer Research and Treatment, 136 (2). pp. 389-398.

Morgan, R, Boxall, A, Harrington, KJ, Simpson, GR, Gillett, C, Michael, A and Pandha, HS (2012) Targeting the HOX/PBX dimer in breast cancer. Breast Cancer Res Treat, 136 (2). pp. 389-398.

Mansfield, D, Pencavel, T, Kyula, JN, Zaidi, S, Roulstone, V, Thway, K, Karapanagiotou, L, Khan, AA, McLaughlin, M, Touchefeu, Y, Seth, R, Melcher, AA, Vile, RG, Pandha, HS and Harrington, KJ (2012) Oncolytic Vaccinia virus and radiotherapy in head and neck cancer. Oral Oncol.

Roulstone, V, Twigger, K, Zaidi, S, Pencavel, T, Kyula, JN, White, C, McLaughlin, M, Seth, R, Karapanagiotou, EM, Mansfield, D, Coffey, M, Nuovo, G, Vile, RG, Pandha, HS, Melcher, AA and Harrington, KJ (2012) Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin-paclitaxel doublet chemotherapy. Gene Ther.

Donnelly, O, Vile, R, Pandha, H, Harrington, K and Melcher, A (2012) The hitchhiker's guide to virotherapy. Oncotarget, 3 (8). pp. 735-736.

Adair, RA, Roulstone, V, Scott, KJ, Morgan, R, Nuovo, GJ, Fuller, M, Beirne, D, West, EJ, Jennings, VA, Rose, A, Kyula, J, Fraser, S, Dave, R, Anthoney, DA, Merrick, A, Prestwich, R, Aldouri, A, Donnelly, O, Pandha, H, Coffey, M, Selby, P, Vile, R, Toogood, G, Harrington, K and Melcher, AA (2012) Cell carriage, delivery, and selective replication of an oncolytic virus in tumor in patients. Sci Transl Med, 4 (138).

Karapanagiotou, EM, Roulstone, V, Twigger, K, Ball, M, Tanay, M, Nutting, C, Newbold, K, Gore, ME, Larkin, J, Syrigos, KN, Coffey, M, Thompson, B, Mettinger, K, Vile, RG, Pandha, HS, Hall, GD, Melcher, AA, Chester, J and Harrington, KJ (2012) Phase I/II Trial of Carboplatin and Paclitaxel Chemotherapy in Combination with Intravenous Oncolytic Reovirus in Patients with Advanced Malignancies CLINICAL CANCER RESEARCH, 18 (7). pp. 2080-2089.

Pulido, J, Kottke, T, Thompson, J, Galivo, F, Wongthida, P, Diaz, RM, Rommelfanger, D, Ilett, E, Pease, L, Pandha, H, Harrington, K, Selby, P, Melcher, A and Vile, R (2012) Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma Nature Biotechnology, 30 (4). pp. 337-343.

Simpson, GR, Horvath, A, Annels, NE, Pencavel, T, Metcalf, S, Seth, R, Peschard, P, Price, T, Coffin, RS, Mostafid, H, Melcher, AA, Harrington, KJ and Pandha, HS (2012) Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for superficial bladder cancer BRITISH JOURNAL OF CANCER, 106 (3). pp. 496-507.

Hall, K, Scott, KJ, Rose, A, Desborough, M, Harrington, K, Pandha, H, Parrish, C, Vile, R, Coffey, M, Bowen, D, Errington-Mais, F and Melcher, AA (2012) Reovirus-mediated cytotoxicity and enhancement of innate immune responses against acute myeloid leukemia. Biores Open Access, 1 (1). pp. 3-15.

Twigger, K, Roulstone, V, Kyula, J, Karapanagiotou, EM, Syrigos, KN, Morgan, R, White, C, Bhide, S, Nuovo, G, Coffey, M, Thompson, B, Jebar, A, Errington, F, Melcher, AA, Vile, RG, Pandha, HS and Harrington, KJ (2012) Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway. BMC Cancer, 12.

Donnelly, OG, Errington-Mais, F, Steele, L, Hadac, E, Jennings, V, Scott, K, Peach, H, Phillips, RM, Bond, J, Pandha, H, Harrington, K, Vile, R, Russell, S, Selby, P and Melcher, AA (2011) Measles virus causes immunogenic cell death in human melanoma. Gene Ther.

Donnelly, OG, Errington-Mais, F, Prestwich, R, Harrington, K, Pandha, H, Vile, R and Melcher, AA (2011) Recent Clinical Experience With Oncolytic Viruses. Curr Pharm Biotechnol.

Kottke, T, Errington, F, Pulido, J, Galivo, F, Thompson, J, Wongthida, P, Diaz, RM, Chong, H, Ilett, E, Chester, J, Pandha, H, Harrington, K, Selby, P, Melcher, A and Vile, R (2011) Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors. Nat Med, 17 (7). pp. 854-859.

Ilett, EJ, Barcena, M, Errington-Mais, F, Griffin, S, Harrington, KJ, Pandha, HS, Coffey, M, Selby, PJ, Limpens, RWAL, Mommaas, M, Hoeben, RC, Vile, RG and Melcher, AA (2011) Internalization of Oncolytic Reovirus by Human Dendritic Cell Carriers Protects the Virus from Neutralization CLINICAL CANCER RESEARCH, 17 (9). pp. 2767-2776.

Steele, L, Errington, F, Prestwich, R, Ilett, E, Harrington, K, Pandha, H, Coffey, M, Selby, P, Vile, R and Melcher, A (2011) Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-kappa B mediated and supports innate and adaptive anti-tumour immune priming MOLECULAR CANCER, 10, ARTN 20.

Heinemann, L, Simpson, GR, Boxall, A, Kottke, T, Relph, KL, Vile, R, Melcher, A, Prestwich, R, Harrington, KJ, Morgan, R and Pandha, HS (2011) Synergistic effects of oncolytic reovirus and docetaxel chemotherapy in prostate cancer. BMC Cancer, 11.

Heinemann, L, Simpson, GR, Annels, NE, Vile, R, Melcher, A, Prestwich, R, Harrington, KJ and Pandha, HS (2010) The Effect of Cell Cycle Synchronization on Tumor Sensitivity to Reovirus Oncolysis MOLECULAR THERAPY, 18 (12). pp. 2085-2093.

Ismail, M, Morgan, R, Harrington, K, Davies, J and Pandha, H (2010) Immunoregulatory effects of freeze injured whole tumour cells on human dendritic cells using an in vitro cryotherapy model CRYOBIOLOGY, 61 (3). pp. 268-274.

Comins, C, Spicer, J, Protheroe, A, Roulstone, V, Twigger, K, White, CM, Vile, R, Melcher, A, Coffey, MC, Mettinger, KL, Nuovo, G, Cohn, DE, Phelps, M, Harrington, KJ and Pandha, HS (2010) REO-10: A Phase I Study of Intravenous Reovirus and Docetaxel in Patients with Advanced Cancer CLINICAL CANCER RESEARCH, 16 (22). pp. 5564-5572.

Hingorani, M, White, CL, Zaidi, S, Pandha, HS, Melcher, AA, Bhide, SA, Nutting, CM, Syrigos, KN, Vile, RG, Vassaux, G and Harrington, KJ (2010) Therapeutic Effect of Sodium Iodide Symporter Gene Therapy Combined With External Beam Radiotherapy and Targeted Drugs That Inhibit DNA Repair MOLECULAR THERAPY, 18 (9). pp. 1599-1605.

Pencavel, T, Seth, R, Hayes, A, Melcher, A, Pandha, H, Vile, R and Harrington, KJ (2010) Locoregional intravascular viral therapy of cancer: precision guidance for Paris's arrow? GENE THERAPY, 17 (8). pp. 949-960.

Harrington, KJ, Karapanagiotou, EM, Roulstone, V, Twigger, KR, White, CL, Vidal, L, Beirne, D, Prestwich, R, Newbold, K, Ahmed, M, Thway, K, Nutting, CM, Coffey, M, Harris, D, Vile, RG, Pandha, HS, DeBono, JS and Melcher, AA (2010) Two-Stage Phase I Dose-Escalation Study of Intratumoral Reovirus Type 3 Dearing and Palliative Radiotherapy in Patients with Advanced Cancers CLINICAL CANCER RESEARCH, 16 (11). pp. 3067-3077.

Karapanagiotou, EM, Chester, JD, Pandha, HS, Gill, GM, Coffey, MC, Mettinger, K and Harrington, KJ (2010) A phase I/II study of oncolytic reovirus plus carboplatin/paclitaxel in patients with advanced solid cancers with emphasis on squamous cell carcinoma of the head and neck(SCCHN) JOURNAL OF CLINICAL ONCOLOGY, 28 (15).

Kottke, T, Hall, G, Pulido, J, Diaz, RM, Thompson, J, Chong, H, Selby, P, Coffey, M, Pandha, H, Chester, J, Melcher, A, Harrington, K and Vile, R (2010) Antiangiogenic cancer therapy combined with oncolytic virotherapy leads to regression of established tumors in mice JOURNAL OF CLINICAL INVESTIGATION, 120 (5). pp. 1551-1560.

Harrington, KJ, Vile, RG, Melcher, A, Chester, J and Pandha, HS (2010) Clinical trials with oncolytic reovirus: Moving beyond phase I into combinations with standard therapeutics CYTOKINE & GROWTH FACTOR REVIEWS, 21 (2-3). pp. 91-98.

Morgan, Richard, Plowright, L, Harrington, KJ, Michael, Agnieszka and Pandha, Hardev (2010) Targeting HOX and PBX transcription factors in ovarian cancer BMC CANCER, 10, ARTN 8.

Hingorani, M, Spitzweg, C, Vassaux, G, Newbold, K, Melcher, A, Pandha, H, Vile, R and Harrington, K (2010) The Biology of the Sodium Iodide Symporter and its Potential for Targeted Gene Delivery CURR CANCER DRUG TAR, 10 (2). pp. 242-267.

Prestwich, RJ, Errington, F, Diaz, RM, Pandha, HS, Harrington, KJ, Melcher, AA and Vile, RG (2009) The Case of Oncolytic Viruses Versus the Immune System: Waiting on the Judgment of Solomon HUMAN GENE THERAPY, 20 (10). pp. 1119-1132.

Ismail, M, Morgan, R, Harrington, K, Davies, J and Pandha, H (2009) Enhancing prostate cancer cryotherapy using tumour necrosis factor related apoptosis-inducing ligand (TRAIL) sensitisation in an in vitro cryotherapy model CRYOBIOLOGY, 59 (2). pp. 207-213.

Prestwich, RJ, Errington, F, Steele, LP, Ilett, EJ, Morgan, RSM, Harrington, KJ, Pandha, HS, Selby, PJ, Vile, RG and Melcher, AA (2009) Reciprocal Human Dendritic Cell-Natural Killer Cell Interactions Induce Antitumor Activity Following Tumor Cell Infection by Oncolytic Reovirus JOURNAL OF IMMUNOLOGY, 183 (7). pp. 4312-4321.

Pandha, Hardev, Heinemann, Lucy, Simpson, Guy, Melcher, A, Prestwich, R, Errington, F, Coffey, M, Harrington, KJ and Morgan, Richard (2009) Synergistic Effects of Oncolytic Reovirus and Cisplatin Chemotherapy in Murine Malignant Melanoma Clinical Cancer Research, 15 (19). pp. 6158-6166.

Prestwich, RJ, Ilett, EJ, Errington, F, Diaz, RM, Steele, LP, Kottke, T, Thompson, J, Galivo, F, Harrington, KJ, Pandha, HS, Selby, PJ, Vile, RG and Melcher, AA (2009) Immune-Mediated Antitumor Activity of Reovirus Is Required for Therapy and Is Independent of Direct Viral Oncolysis and Replication CLINICAL CANCER RESEARCH, 15 (13). pp. 4374-4381.

Ismail, M, Bokaee, S, Morgan, R, Davies, J, Harrington, KJ and Pandha, H (2009) Inhibition of the aquaporin 3 water channel increases the sensitivity of prostate cancer cells to cryotherapy (vol 100, pg 1889, 2009) BRITISH JOURNAL OF CANCER, 101 (3). p. 549.

Ismail, M, Bokaee, S, Davies, J, Harrington, KJ and Pandha, H (2009) Inhibition of the aquaporin 3 water channel increases the sensitivity of prostate cancer cells to cryotherapy BRITISH JOURNAL OF CANCER, 100 (12). pp. 1889-1895.

Pandha, H, Melcher, A, Harrington, K and Vile, R (2009) Oncolytic Viruses: Time to Compare, Contrast, and Combine? MOLECULAR THERAPY, 17 (6). pp. 934-935.

Ilett, EJ, Prestwich, RJ, Kottke, T, Errington, F, Thompson, JM, Harrington, KJ, Pandha, HS, Coffey, M, Selby, PJ, Vile, RG and Melcher, AA (2009) Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity GENE THERAPY, 16 (5). pp. 689-699.

Pandha, H, D'Ambrosio, C, Heenan, S, Hyde, N, Di Palma, S, Nutting, C, Relph, K and Harrington, K (2009) Indium-labelled Autologous Dendritic Cells Migrate to Local Lymph Nodes after Intratumoural Injection in Head and Neck Cancer Patients CLINICAL ONCOLOGY, 21 (4). pp. 363-364.

Plowright, L, Harrington, KJ, Pandha, HS and Morgan, R (2009) HOX transcription factors are potential therapeutic targets in non-small-cell lung cancer (targeting HOX genes in lung cancer) BRITISH JOURNAL OF CANCER, 100 (3). pp. 470-475.

Agrawal, VK, Copeland, KM, Barbachano, Y, Rahim, A, Seth, R, White, CL, Hingorani, M, Nutting, CM, Kelly, M, Harris, P, Pandha, H, Melcher, AA, Vile, RG, Porter, C and Harrington, KJ (2009) Microvascular free tissue transfer for gene delivery: in vivo evaluation of different routes of plasmid and adenoviral delivery GENE THERAPY, 16 (1). pp. 78-92.

Plowright, L, Harrington, K, Pandha, HS and Morgan, R (2009) HOX transcription factors are potential therapeutic targets in non-small cell lung cancer British Journal of Cancer.

Hingorani, M, White, CL, Merron, A, Peerlinck, I, Gore, ME, Slade, A, Scott, SD, Nutting, CM, Pandha, HS, Melcher, AA, Vile, RG, Vassaux, G and Harrington, KJ (2008) Inhibition of Repair of Radiation-Induced DNA Damage Enhances Gene Expression from Replication-Defective Adenoviral Vectors CANCER RESEARCH, 68 (23). pp. 9771-9778.

Yap, TA, Brunetto, A, Pandha, H, Harrington, K and de Bono, JS (2008) Reovirus therapy in cancer: has the orphan virus found a home? EXPERT OPINION ON INVESTIGATIONAL DRUGS, 17 (12). pp. 1925-1935.

Prestwich, RJ, Errington, F, Ilett, EJ, Morgan, RSM, Scott, KJ, Kottke, T, Thompson, J, Morrison, EE, Harrington, KJ, Pandha, HS, Selby, PJ, Vile, RG and Melcher, AA (2008) Tumor Infection by Oncolytic Reovirus Primes Adaptive Antitumor Immunity CLINICAL CANCER RESEARCH, 14 (22). pp. 7358-7366.

Vidal, L, Pandha, HS, Yap, TA, White, CL, Twigger, K, Vile, RG, Melcher, A, Coffey, M, Harrington, KJ and DeBono, JS (2008) A Phase I Study of Intravenous Oncolytic Reovirus Type 3 Dearing in Patients with Advanced Cancer CLINICAL CANCER RESEARCH, 14 (21). pp. 7127-7137.

Shears, L, Plowright, L, Harrington, K, Pandha, HS and Morgan, R (2008) Disrupting the Interaction Between HOX and PBX Causes Necrotic and Apoptotic Cell Death in the Renal Cancer Lines CaKi-2 and 769-P J UROLOGY, 180 (5). pp. 2196-2201.

Prestwich, RJ, Harrington, KJ, Pandha, HS, Vile, RG, Melcher, AA and Errington, F (2008) Oncolytic viruses: a novel form of immunotherapy EXPERT REVIEW OF ANTICANCER THERAPY, 8 (10). pp. 1581-1588.

Errington, F, White, CL, Twigger, KR, Rose, A, Scott, K, Steele, L, Ilett, LJ, Prestwich, R, Pandha, HS, Coffey, M, Selby, P, Vile, R, Harrington, KJ and Melcher, AA (2008) Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma GENE THERAPY, 15 (18). pp. 1257-1270.

Comins, C, Heinemann, L, Harrington, K, Melcher, A, De Bono, J and Pandha, H (2008) Reovirus: Viral therapy for cancer 'as nature intended' CLINICAL ONCOLOGY, 20 (7). pp. 548-554.

Harrington, KJ, Melcher, A, Vassaux, G, Pandha, HS and Vile, RG (2008) Exploiting synergies between radiation and oncolytic viruses CURRENT OPINION IN MOLECULAR THERAPEUTICS, 10 (4). pp. 362-370.

Hingorani, M, White, CL, Zaidi, S, Merron, A, Peerlinck, I, Gore, ME, Nutting, CM, Pandha, HS, Melcher, AA, Vile, RG, Vassaux, G and Harrington, KJ (2008) Radiation-mediated up-regulation of gene expression from replication-defective adenoviral vectors: Implications for sodium iodide symporter gene therapy CLINICAL CANCER RESEARCH, 14 (15). pp. 4915-4924.

White, CL, Twigger, KR, Vidal, L, De Bono, JS, Coffey, M, Heinemann, L, Morgan, R, Merrick, A, Errington, F, Vile, RG, Melcher, AA, Pandha, HS and Harrington, KJ (2008) Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial GENE THERAPY, 15 (12). pp. 911-920.

Errington, F, Steele, L, Prestwich, R, Harrington, KJ, Pandha, HS, Vidal, L, de Bono, J, Selby, P, Coffey, M, Vile, R and Melcher, A (2008) Reovirus activates human dendritic cells to promote innate antitumor immunity JOURNAL OF IMMUNOLOGY, 180 (9). pp. 6018-6026.

White, CL, Menghistu, T, Twigger, KR, Searle, PF, Bhide, SA, Vile, RG, Melcher, AA, Pandha, HS and Harrington, KJ (2008) Escherichia coli nitroreductase plus CB1954 enhances the effect of radiotherapy in vitro and in vivo GENE THERAPY, 15 (6). pp. 424-433.

Twigger, K, Vidal, L, White, CL, De Bono, JS, Bhide, S, Coffey, M, Thompson, B, Vile, RG, Heinemann, L, Pandha, HS, Errington, F, Melcher, AA and Harrington, KJ (2008) Enhanced in vitro and in vivo cytotoxicity of combined reovirus and radiotherapy CLINICAL CANCER RESEARCH, 14 (3). pp. 912-923.

Qiao, J, Wang, H, Kottke, T, White, C, Twigger, K, Diaz, RM, Thompson, J, Selby, P, de Bono, J, Melcher, A, Pandha, H, Coffey, M, Vile, R and Harrington, K (2008) Cyclophosphamide facilitates antitumor efficacy against subcutaneous tumors following intravenous delivery of reovirus CLINICAL CANCER RESEARCH, 14 (1). pp. 259-269.

Prestwich, RJ, Errington, F, Harrington, KJ, Pandha, HS, Selby, P and Melcher, A (2008) Oncolytic viruses: do they have a role in anti-cancer therapy? Clin Med Oncol, 2. pp. 83-96.

Gore, ME, Nutting, CM, Pandha, HS, Melcher, AA, Vile, RG and Harrington, KJ (2008) T-cell responses to survivin in cancer patients undergoing radiation therapy Clinical Cancer Research, 14 (15). p. 4883.

Harris, D, Vidal, L, Melcher, A, Newbold, K, Anthony, A, Karavasilis, V, Agarwal, R, White, C, Twigger, K, Coffey, M, Mettinger, K, Thompson, B, Pandha, H, De-Bono, J and Harrington, K (2007) A Phase I study to evaluate the feasibility, safety and biological effects of intratumoural administration of wild-type Reovirus (REOLYSIN (R)) in combination with radiation in patients with advanced malignancies. MOLECULAR CANCER THERAPEUTICS, 6 (12). 3458S-3458S.

Hu, JC, Coffin, RS, Graham, NJ, Groves, N, Guest, PJ, Harrington, KJ, James, ND, Love, CA, McNeish, I, Medley, LC, Michael, A, Nutting, CM, Pandha, HS, Shorrock, CA, Simpson, J, Steiner, J, Steven, NM, Wright, D and Coombes, RC (2006) A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor Clin Cancer Res, 12 (22). pp. 6737-6747.

Pandha, H, Birchall, L, Meyer, B, Wilson, N, Relph, K, Anderson, C and Harrington, K (2006) Antitumor effects of aminobisphosphonates on renal cell carcinoma cell lines JOURNAL OF UROLOGY, 176 (5). pp. 2255-2261.

Yap, TA, Vidal, L, Pandha, H, Spicer, J, Digue, L, Coffey, M, Thompson, B, Kaye, SB, Harrington, KJ and De-Bono, JS (2006) A phase I study of wild-type reovirus, which selectively replicates in cells expressing activated Ras, administered intravenously to patients with advanced cancer EJC SUPPLEMENTS, 4 (12). p. 108.

Relph, KL, Harrington, KJ and Pandha, H (2005) Adenoviral strategies for the gene therapy of cancer SEMINARS IN ONCOLOGY, 32 (6). pp. 573-582.

Relph, KL, Harrington, K and Pandha, H (2004) Gene Therapy using viral vectors; recent developments and current status in the United Kingdom British Medical Journal.

Book Section

Pandha, HS, Harrington, KJ and Vile, RG (2008) Poxviruses as immunomodulatory cancer therapeutics. In: Viral Therapy of Cancer. UNSPECIFIED. ISBN 0470019220

Conference or Workshop Item

Rajani, K, Shim, K, Parrish, C, Ilett, L, Kottke, T, Pulido, J, Thompson, J, Pandha, H, Harrington, K, Melcher, A, Errington, F, Diaz, R, Coffey, M, Zaidi, S and Vile, R (2015) Combination Therapy of Reovirus and PD-1 Blockade Effectively Establishes Tumor Control Via Innate and Adaptive Immune Responses In: 18th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), 2015-05-13 - 2015-05-16, New Orleans, LA.

Jebar, A, Bentham, M, Errington-Mais, F, Scott, K, Peckham-Cooper, A, Dave, R, Toogood, G, Swinson, D, Ralph, C, Anthoney, A, Coffey, M, Harrington, K, Pandha, H, Vile, R, Selby, P, Melcher, A and Griffin, S (2014) Combined anti-viral and anti-tumour therapy for virus-associated liver cancer In: 8th International Conference on Oncolytic Virus Therapeutics, 2014-04-10 - 2014-04-13, Lincoln Coll & Examinat Sch, Oxford, ENGLAND.

Simpson, GR, Ajaz, M, Launchbury, FA, Bolton, G, Melcher, AA, Harrington, KJ, Au, GG, Shafren, DR and Pandha, HS (2014) Major synergy between Coxsackievirus A21 (CAVATAK (TM)) and radiotherapy or chemotherapy in bladder cancer In: 8th International Conference on Oncolytic Virus Therapeutics, 2014-04-10 - 2014-04-13, Lincoln Coll & Examinat Sch, Oxford, ENGLAND.

Bolton, GC, Simpson, GR, Coffey, M, Harrington, K, Morgan, R, Annels, N, Launchbury, FA, Ajaz, M and Pandha, H (2014) Resistance to Oncolytic Reovirus is associated with high expression of Yes-Associated Protein-1 (YAP-1) in Head and Neck Cancer In: 8th International Conference on Oncolytic Virus Therapeutics, 2014-04-10 - 2014-04-13, Lincoln Coll & Examinat Sch, Oxford, ENGLAND.

Simpson, GR, Annels, N, Ajaz, M, Launchbury, F, Bolton, G, Melcher, AA, Harrington, KJ, Au, G, Shafren, D and Pandha, H (2014) Major synergy between Coxsackievirus A21 (CAVATAK (TM)) and radiotherapy or chemotherapy in bladder cancer In: 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, 2014-11-18 - 2014-11-21, European Org Res & Treatment Canc, Barcelona, SPAIN.

Jebar, A, West, E, Scott, K, Thomson, S, Corns, R, Coffey, MC, Rose, A, Nuovo, G, Ryan, M, Errington-Mais, F, Ralph, C, Twelves, C, Griffin, S, Harrington, KJ, Pandha, HS, Donnely, O, Selby, PJ, Vile, R, Short, S and Melcher, A (2014) Oncolytic wild-type reovirus infection in brain tumors following intravenous administration in patients. In: 50th Annual Meeting of the American-Society-of-Clinical-Oncology, 2014-05-30 - 2014-06-03, Chicago, IL.

Zaidi, S, Blanchard, M, Shim, K, Ilett, E, Kottke, T, Thompson, J, Celis, E, Pandha, H, Selby, P, Melcher, A, Harrington, K and Vile, R (2014) Acquisition of Mutated BRAF Is as a Major Effector of Melanoma Recurrence Which Can Be Targeted By Immuno- or Chemo-Therapy In: 17th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), 2014-05-21 - 2014-05-24, Washington, DC.

Ilett, E, Kottke, T, Donnelly, O, Thompson, J, Willmon, C, Diaz, R, Zaidi, S, Coffey, M, Selby, P, Harrington, K, Pandha, H, Melcher, A and Vile, R (2014) Direct, Cytokine-Conditioned, In Vivo Cell Loading for Systemic Delivery of Oncolytic Viruses In: 17th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), 2014-05-21 - 2014-05-24, Washington, DC.

Alonso-Camino, V, Rajani, K, Kottke, T, Rommelfanger-Konkol, D, Zaidi, S, Thompson, J, Pulido, J, Ilett, L, Selby, P, Pandha, H, Melcher, A, Harrington, K, Diaz, R and Vile, R (2014) The Profile of Tumor Antigens Which Can Be Targeted By Immunotherapy Depends Upon the Tumor's Anatomical Site In: 17th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), 2014-05-21 - 2014-05-24, Washington, DC.

Kottke, T, Donnelly, O, Ilett, E, Thompson, J, Diaz, R, Coffey, M, Selby, P, Pandha, H, Harrington, K, Melcher, A and Vile, R (2013) In Vivo Expansion of a Recipient Population of Cell Carriers Allows for Highly Effective Systemic Delivery of Oncolytic Reovirus Even in the Presence of Neutralizing Antibody In: 16th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), 2013-05-15 - 2013-05-18, Salt Lake City, UT.

Boisgerault, N, Pulido, J, Kottke, T, Donnelly, O, Celis, E, Thompson, J, Diaz, R, Harrington, K, Pandha, H, Selby, P, Melcher, A and Vile, R (2013) Tumor Recurrences Share Immunogenic Antigens across Both Tumor Types and Primary Treatments Which Can Be Therapeutically Targeted with VSV-cDNA Libraries In: 16th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), 2013-05-15 - 2013-05-18, Salt Lake City, UT.

Kottke, T, Donnelly, O, Boisgerault, N, Diaz, R, Rommelfanger-Konkol, D, Pulido, J, Thompson, J, Mukhopadhyay, D, Knutson, K, Behrens, M, Kaspar, R, Coffey, M, Selby, P, Harrington, K, Melcher, A, Pandha, H and Vile, R (2013) Tumor Relapse Is Associated with an Innate Immune Resistant Phenotype across Tumor and Treatment Types Which Can Be Targeted with Rational Second Line Therapies In: 16th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), 2013-05-15 - 2013-05-18, Salt Lake City, UT.

Kottke, T, Donnelly, O, Boisgerault, N, Diaz, R, Thompson, J, Chester, J, Pandha, H, Harrington, K, Melcher, A and Vile, R (2012) Characterization of the Mechanisms of Tumor Dormancy and Recurrence Following Front Line Immuno-, Viro- or Suicide Gene-, Therapy In: 15th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), 2012-05-16 - 2012-05-19, Philadelphia, PA.

Pandha, S, Simpson, GR, Horvath, A, Coffin, RS, Pencavel, T and Harrington, K (2011) Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for superficial bladder cancer (visualised by micro CT) In: Annual Meeting of the Society-of-Academic-and-Research-Surgery, 2011-01-05 - 2011-01-06, Royal Coll Surgery, Dublin, IRELAND.

Karapanagiotou, E, Pandha, HS, Hall, G, Chester, J, Melcher, A, Coffey, M, de Bono, J, Gore, ME, Nutting, CM and Harrington, KJ (2009) Phase I/II trial of oncolytic reovirus (Reolysin) in combination with carboplatin/paclitaxel in patients (pts) with advanced solid cancers In: 45th Annual Meeting of the American-Society-of-Clinical-Oncology, 2009-05-29 - 2009-06-02, Orlando, FL.

Rudman, SM, Comins, C, Mukherji, D, Coffey, M, Mettinger, K, Protheroe, A, Harrington, KJ, Pandha, H and Spicer, JF (2009) Results of a phase I study to evaluate the feasibility, safety, and biological effects of intravenous administration of wild-type reovirus with docetaxel to patients with advanced malignancies In: 45th Annual Meeting of the American-Society-of-Clinical-Oncology, 2009-05-29 - 2009-06-02, Orlando, FL.

Comins, C, Spicer, J, Protheroe, A, Mukherji, D, Coffey, M, Thompson, B, Harrington, K and Pandha, H (2008) A Phase I Study to Evaluate Systemic Wild-type Reovirus (REOLYSIN)(R) in Combination With Docetaxel in Patients With Advanced Malignancies In: 23rd Annual Scientific Meeting of the International-Society-for-Biological-Therapy-of-Cancer, 2008-10-31 - 2008-11-02, San Diego, CA.

Karapanagiotou, E, Pandha, H, Hall, G, Chester, J, Melcher, A, De Bono, J, Gore, M, Nutting, C and Harrington, K (2008) Phase I Trial of Oncolytic Reovirus (Reolysin) in Combination With Carboplatin/Paclitaxel in Patients With Advanced Solid Cancers In: 23rd Annual Scientific Meeting of the International-Society-for-Biological-Therapy-of-Cancer, 2008-10-31 - 2008-11-02, San Diego, CA.

Heinemann, L, Kottke, T, Vile, R, Coffey, MC, Harrington, K, Melcher, A and Pandha, HS (2008) Synergistic Anti-Tumor Activity of Oncolytic Reovirus and Docetaxel in a PC-3 Prostate Cancer Mouse Model In: 23rd Annual Scientific Meeting of the International-Society-for-Biological-Therapy-of-Cancer, 2008-10-31 - 2008-11-02, San Diego, CA.

Simpson, GR, Horvath, A, Harrington, K, Coffin, RS and Pandha, H (2008) Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for superficial bladder cancer In: 20th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, 2008-10-21 - 2008-10-24, Geneva, SWITZERLAND.

Heinemann, L, Simpson, G, Harrington, K, Melcher, A, Coffey, MC and Pandha, HS (2008) Synergistic anti-tumour activity of oncolytic Reovirus and cisplatin in a B16.F10 mouse melanoma model In: 20th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, 2008-10-21 - 2008-10-24, Geneva, SWITZERLAND.

Vidal, L, Pandha, H, Spicer, J, Harrington, KJ, Allen, S, Leader, D, Coffey, M, Thompson, B, Kaye, S and De-Bono, J (2006) A phase I study of reolysin given intravenously to patients with advanced malignancies. In: 42nd Annual Meeting of the American-Society-of-Clinical-Oncology, 2006-06-02 - 2006-06-06, Atlanta, GA.

Vidal, L, Twigger, K, White, C, Coffey, M, Thompson, B, De-Bono, J, Pandha, HS, Melcher, A, Kaye, S and Harrington, KJ (2005) Reovirus enhances radiation cytotoxicity in vitro and in vivo. In: AACR/NCI/EORTC International Conference on Molecular Targets and Cancer Therapeutics, 2005-11-14 - 2005-11-18, Philadelphia, PA.

Vidal, L, Pandha, H, Harrington, K, Fong, P, Shaw, H, Barrett, M, Leader, D, White, C, Twigger, K, Coffey, M, Thompson, B, Kaye, S and De-Bono, J (2005) A phase I study of a wild-type reovirus (Reolysin) given intravenously to patients with advanced malignancies. In: AACR/NCI/EORTC International Conference on Molecular Targets and Cancer Therapeutics, 2005-11-14 - 2005-11-18, Philadelphia, PA.

Book

Pandha, HS, Relph, K and Harrington, K (2008) Treatment of Cancer 5th Edition Chapter Gene Therapy UNSPECIFIED. ISBN 0340912219

Pandha, HS, Harrington, KJ and Vile, RG (2008) Viral Therapy of Cancer John Wiley. ISBN 0470019220

This list was generated on Sun Sep 24 05:18:58 2017 UTC.

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