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Items where Author is "Hall, B"

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Number of items: 17.

Article

Ogbechi, J, Ruf, MT, Hall, BS, Bodman-Smith, K, Vogel, M, Wu, HL, Stainer, A, Esmon, CT, Ahnström, J, Pluschke, G and Simmonds, RE (2015) Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions. PLoS Pathog, 11 (7).

de Carvalho, AS, Salomao, K, de Castro, SL, Conde, TR, da Silva Zamith, HP, Caffarena, ER, Hall, BS, Wilkinson, SR and Boechat, N (2014) Megazol and its bioisostere 4H-1,2,4-triazole: comparing the trypanocidal, cytotoxic and genotoxic activities and their in vitro and in silico interactions with the Trypanosoma brucei nitroreductase enzyme MEMORIAS DO INSTITUTO OSWALDO CRUZ, 109 (3). pp. 315-323.

Hall, BS, Hill, K, McKenna, M, Ogbechi, J, High, S, Willis, AE and Simmonds, RE (2014) The Pathogenic mechanism of the mycobacterium ulcerans virulence factor, mycolactone, deends on blockade of protein translocation intot he ER PLOS PATHOGENS, 10 (4).

Hall, B and Simmonds, R (2014) Pleiotropic molecular effects of the Mycobacterium ulcerans virulence factor mycolactone underlying the cell death and immunosuppression seen in Buruli ulcer. Biochem Soc Trans, 42 (1). pp. 177-183.

Roussaki, M, Hall, B, Lima, SC, da Silva, AC, Wilkinson, S and Detsi, A (2013) Synthesis and anti-parasitic activity of a novel quinolinone-chalcone series BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 23 (23). pp. 6436-6441.

Voak, AA, Gobalakrishnapillai, V, Seifert, K, Balczo, E, Hu, L, Hall, BS and Wilkinson, SR (2013) An essential type I nitroreductase from Leishmania major can be used to activate leishmanicidal prodrugs. J Biol Chem.

Bot, C, Hall, BS, Alvarez, G, Di Maio, R, González, M, Cerecetto, H and Wilkinson, SR (2013) Evaluating 5-nitrofurans as trypanocidal agents. Antimicrob Agents Chemother.

Hall, BS, Meredith, EL and Wilkinson, SR (2012) Targeting the substrate preference of a type I nitroreductase to develop anti-trypanosomal quinone-based prodrugs. Antimicrob Agents Chemother.

Mejia, AM, Hall, BS, Taylor, MC, Gómez-Palacio, A, Wilkinson, SR, Triana-Chávez, O and Kelly, JM (2012) Benznidazole-Resistance in Trypanosoma cruzi Is a Readily Acquired Trait That Can Arise Independently in a Single Population. J Infect Dis.

Hall, BS and Wilkinson, SR (2012) Activation of Benznidazole by Trypanosomal Type I Nitroreductases Results in Glyoxal Formation ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 56 (1). pp. 115-123.

Wilkinson, SR, Bot, C, Kelly, JM and Hall, BS (2011) Trypanocidal Activity of Nitroaromatic Prodrugs: Current Treatments and Future Perspectives CURRENT TOPICS IN MEDICINAL CHEMISTRY, 11 (16). pp. 2072-2084.

Hu, L, Wu, X, Han, J, Chen, L, Vass, SO, Browne, P, Hall, BS, Bot, C, Gobalakrishnapillai, V, Searle, PF, Knox, RJ and Wilkinson, SR (2011) Synthesis and structure-activity relationships of nitrobenzyl phosphoramide mustards as nitroreductase-activated prodrugs BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 21 (13). pp. 3986-3991.

Hall, BS, Bot, C and Wilkinson, SR (2011) Nifurtimox Activation by Trypanosomal Type I Nitroreductases Generates Cytotoxic Nitrile Metabolites JOURNAL OF BIOLOGICAL CHEMISTRY, 286 (15). pp. 13088-13095.

Bot, C, Hall, BS, Bashir, N, Taylor, MC, Helsby, NA and Wilkinson, SR (2010) Trypanocidal Activity of Aziridinyl Nitrobenzamide Prodrugs ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 54 (10). pp. 4246-4252.

Hall, BS, Wu, X, Hu, L and Wilkinson, SR (2010) Exploiting the Drug-Activating Properties of a Novel Trypanosomal Nitroreductase ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 54 (3). pp. 1193-1199.

Hall, BS, Gabernet-Castello, C, Voak, A, Goulding, D, Natesan, SK and Field, MC (2006) TbVps34, the trypanosome orthologue of Vps34, is required for Golgi complex segregation JOURNAL OF BIOLOGICAL CHEMISTRY, 281 (37). pp. 27600-27612.

Book Section

Hall, BS, Simmonds, R, Benbow, ME, Mosi, L, Roberts, S and Williamso Jordan, H (2015) Mycobacterium ulcerans and Buruli Ulcer In: Human Emerging and Re-emerging Infections: Viral and Parasitic Infections, Volume I. John Wiley and Sons, Hoboken, NJ, USA.

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