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Items where Author is "Dorling, A"

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Article

Karegli, J, Melchionna, T, Farrar, CA, Greenlaw, R, Smolarek, D, Horsfield, C, Charif, R, McVey, John, Dorling, A, Sacks, SH and Smith, RAG (2017) Thrombalexins: Cell-Localized Inhibition of Thrombin and its Effects in a Model of HighRisk Renal Transplantation American Journal of Transplantation, 17 (1). pp. 272-280.

Chen, D, Xia, M, Hayford, C, Tham, E-L, Semik, V, Hurst, S, Chen, Y, Tam, HH, Pan, J, Wang, Y, Tan, X, Lan, H-Y, Shen, H, Kakkar, VV, Xu, Q, McVey, JH and Dorling, A (2015) Expression of Human Tissue Factor Pathway Inhibitor on Vascular Smooth Muscle Cells Inhibits Secretion of Macrophage Migration Inhibitory Factor and Attenuates Atherosclerosis in ApoE(-/-) Mice CIRCULATION, 131 (15). 1350-U101.

Chen, D, McVey, JH and Dorling, A (2013) Enhanced effect of inhibition of thrombin on endothelium in murine endotoxaemia: Specific inhibition of thrombocytopenia Thrombosis Research, 132 (6). pp. 750-756.

Shrivastava, S, Ma, L, Tham, E-L, McVey, JH, Chen, D and Dorling, A (2013) Protease-activated receptor-2 signalling by tissue factor on dendritic cells suppresses antigen-specific CD4(+) T-cell priming IMMUNOLOGY, 139 (2). pp. 219-226.

Chen, D, Ma, L, Tham, E-L, Maresh, S, Lechler, RI, Mcvey, JH and Dorling, A (2013) Fibrocytes mediate intimal hyperplasia post-vascular injury and are regulated by two tissue factor-dependent mechanisms JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 11 (5). pp. 963-974.

Chen, D, Shrivastava, S, Ma, L, Tham, ELL, Abrahams, J, Coe, JD, Scott, D, Lechler, RI, McVey, JH and Dorling, A (2012) Inhibition of thrombin receptor signaling on α-smooth muscle actin(+) CD34(+) progenitors leads to repair after murine immune vascular injury. Arterioscler Thromb Vasc Biol, 32 (1). pp. 42-49.

Lin, CC, Chen, D, McVey, JH, Cooper, DKC and Dorling, A (2008) Expression of tissue factor and initiation of clotting by human platelets and monocytes after incubation with porcine endothelial cells TRANSPLANTATION, 86 (5). pp. 702-709.

Chen, D, Carpenter, A, Abrahams, J, Chambers, RC, Lechler, RI, McVey, JH and Dorling, A (2008) Protease-activated receptor 1 activation is necessary for monocyte chemoattractant protein 1-dependent leukocyte recruitment in vivo JOURNAL OF EXPERIMENTAL MEDICINE, 205 (8). pp. 1739-1746.

Chen, D, Abrahams, JM, Smith, LM, Mcvey, JH, Lechler, RI and Dorling, A (2008) Regenerative repair after endoluminal injury in mice with specific antagonism of protease activated receptors on CD34(+) vascular progenitors BLOOD, 111 (8). pp. 4155-4164.

Shrivastava, S, McVey, JH and Dorling, A (2007) The interface between coagulation and immunity AMERICAN JOURNAL OF TRANSPLANTATION, 7 (3). pp. 499-506.

Chen, D, Weber, M, Shiels, PG, Dong, R, Webster, Z, Mcvey, JH, Kemball-Cook, G, Tuddenham, EGD, Lechler, RI and Dorling, A (2006) Postinjury vascular intimal hyperplasia in mice is completely inhibited by CD34+bone marrow-derived progenitor cells expressing membrane-tethered anticoagulant fusion proteins JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 4 (10). pp. 2191-2198.

Mumford, AD, Chen, D, Dorling, A, Kemball-Cook, G and McVey, JH (2005) Generation of a polyclonal rabbit anti-mouse tissue factor antibody by nucleic acid immunisation. Thromb Haemost, 93 (1). pp. 160-164.

Chen, DX, Weber, M, McVey, JH, Kemball-Cook, G, Tuddenham, EGD, Lechler, RI and Dorling, A (2004) Complete inhibition of acute humoral rejection using regulated expression of membrane-tethered anticoagulants on xenograft endothelium AMERICAN JOURNAL OF TRANSPLANTATION, 4 (12). pp. 1958-1963.

Chen, DX, Giannopoulos, K, Shiels, PG, Webster, Z, McVey, JH, Kemball-Cook, G, Tuddenham, E, Moore, M, Lechler, R and Dorling, A (2004) Inhibition of intravascular thrombosis in murine endotoxemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium BLOOD, 104 (5). pp. 1344-1349.

Chen, DX, Riesbeck, K, McVey, JH, Kemball-Cook, G, Tuddenham, EGD, Lechler, RI and Dorling, A (2001) Human thrombin and FXa mediate porcine endothelial cell activation; modulation by expression of TFPI-CD4 and hirudin-CD4 fusion proteins XENOTRANSPLANTATION, 8 (4). pp. 258-265.

Dorling, A, Chen, D, Riesbeck, K, McVey, J, Kemball-Cook, G, Tuddenham, EG and Lechler, RI (2000) Regulated endothelial cell expression of novel anticoagulants: a strategy for the prevention and therapy of intravascular thrombosis. Transplant Proc, 32 (5).

Chen, DX, Riesbeck, K, McVey, JH, Kemball-Cook, G, Tuddenham, EGD, Lechler, RI and Dorling, A (1999) Regulated inhibition of coagulation by porcine endothelial cells expressing: P-selectin-tagged hirudin and tissue factor pathway inhibitor fusion proteins TRANSPLANTATION, 68 (6). pp. 832-839.

Chen, DX, Riesbeck, K, Kemball-Cook, G, McVey, JH, Tuddenham, EGD, Lechler, RI and Dorling, A (1999) Inhibition of tissue factor-dependent and -independent coagulation by cell surface expression of novel anticoagulant fusion proteins TRANSPLANTATION, 67 (3). pp. 467-474.

Riesbeck, K, Chen, DX, Kemball-Cook, G, McVey, JH, George, AJT, Tuddenham, EGD, Dorling, A and Lechler, RI (1998) Expression of hirudin fusion proteins in mammalian cells - A strategy for prevention of intravascular thrombosis CIRCULATION, 98 (24). pp. 2744-2752.

Riesbeck, K, Dorling, A, KemballCook, G, McVey, JH, Jones, M, Tuddenham, EGD and Lechler, RI (1997) Human tissue factor pathway inhibitor fused to CD4 binds both FXa and TF/FVIIa at the cell surface THROMBOSIS AND HAEMOSTASIS, 78 (6). pp. 1488-1494.

Conference or Workshop Item

Melchionna, T, Karegli, J, Farrar, CA, McVey, JH, Dorling, A, Sacks, SH and Smith, RAG (2010) Integrating cytotopic strategy in transplantation: (1) Design of locally-acting coagulation inhibitors for use with anti-complement therapeutics In: 23rd International National Complement Workshop, 2010-08-01 - 2010-08-05, New York, NY.

Smith, RAG, Karegli, J, Melchionna, T, Farrar, CA, McVey, JH, Dorling, A and Sacks, SH (2009) Towards an integrated cytotopic strategy for graft modification in transplantation-Complement and coagulation In: 12th European Meeting on Complement in Human Disease, 2009-09-05 - 2009-09-08, Visegrad, HUNGARY.

Lin, CC, McVey, JH and Dorling, A (2007) Expression of tissue factor and initiation of clotting by human platelets and monocytes after incubation with porcine endothelial cells In: Joint Meeting of the International-Xenotransplantation-Association/International-Pancrcas-and-Islet-Transplant-Association/Cell-Transplant-Society, 2007-09-15 - 2007-09-20, Minneapolis, MN.

Daxin, C, Riesbeck, K, McVey, J, Kembell-Cook, G, Tuddenham, EGD, Lechler, RI and Dorling, A (2000) Expression of novel anticoagulant fusion proteins inhibits factor Xa- and thrombin-induced activation of porcine vascular endothelial cells.

Chen, D, Riesbeck, K, McVey, JH, Kemball-Cook, G, Tuddenham, EGD, Lechler, RI and Dorling, A (1999) Regulated endothelial cell expression of novel molecules with anticoagulant properties: A strategy for the prevention and therapy of vascular rejection

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