Organ-specific production of alkaloids from bulbs and seeds of Crinum stuhlmannii subsp. delagoense (Amaryllidaceae)

Moodley, N., Crouch, N.R. Crouch, Bastida, J., Mas-Claret, E., Houghton, P. and Mulholland, D.A. (2020) Organ-specific production of alkaloids from bulbs and seeds of Crinum stuhlmannii subsp. delagoense (Amaryllidaceae) South African Journal of Botany.

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Abstract

The phytochemistry of both bulbs and seeds of the ethnomedicinal Crinum stuhlmannii subsp. delagoense (Amaryllidaceae) was studied, sourced from a single location simultaneously. Eight alkaloids, including two previously unreported ones, N-methyl-haemanthamide (nivanine), and N-methyl-ent-delagoenine, were isolated along with lycorine, 8,9-methylenedioxophenanthridine, 6-hydroxycrinamine, 6-ethoxycrinamine, haemanthamine and hamayne. Compounds isolated were tested for acetylcholinesterase inhibition.

Item Type:	Article
Divisions :	Faculty of Engineering and Physical Sciences > Chemistry
Authors :	Name Email ORCID Moodley, N. Crouch, N.R. Crouch Bastida, J. Mas-Claret, E. e.masclaret@surrey.ac.uk Houghton, P. Mulholland, D.A. D.Mulholland@surrey.ac.uk
Date :	2020
Copyright Disclaimer :	© 2020. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
Uncontrolled Keywords :	Acetylcholinesterase inhibition; Amaryllidaceae; Crinum stuhlmannii subsp. delagoense; N-methyl-haemanthamide; 6β-ethoxycrinamine; Hamayne; Haemanthamine; 6-hydroxycrinamine; Lycorine; N-methyl-ent-delagoenine; 8,9-methylenedioxophenanthridine; Nivanine
Related URLs :	Publisher
Depositing User :	Clive Harris
Date Deposited :	02 Sep 2020 13:55
Last Modified :	02 Sep 2020 13:55
URI:	http://epubs.surrey.ac.uk/id/eprint/858526

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