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Recent developments in non-coplanar radiotherapy

Smyth, Gregory, Evans, Philip M., Bamber, Jeffrey C. and Bedford, James L. (2019) Recent developments in non-coplanar radiotherapy The British Journal of Radiology, 92 (1097), 20180908.

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This paper gives an overview of recent developments in non-coplanar intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT). Modern linear accelerators are capable of automating motion around multiple axes, allowing efficient delivery of highly non-coplanar radiotherapy techniques. Novel techniques developed for C-arm and non-standard linac geometries, methods of optimization, and clinical applications are reviewed. The additional degrees of freedom are shown to increase the therapeutic ratio, either through dose escalation to the target or dose reduction to functionally important organs at risk, by multiple research groups. Although significant work is still needed to translate these new non-coplanar radiotherapy techniques into the clinic, clinical implementation should be prioritized. Recent developments in non-coplanar radiotherapy demonstrate that it continues to have a place in modern cancer treatment.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Electronic Engineering
Authors :
Smyth, Gregory
Evans, Philip
Bamber, Jeffrey C.
Bedford, James L.
Date : 1 February 2019
Funders : National Institute for Health Research (NIHR), Cancer Research UK
DOI : 10.1259/bjr.20180908
Grant Title : Cancer Research UK
Copyright Disclaimer : © 2019 The Authors. Published by the British Institute of Radiology under the terms of the Creative Commons Attribution 4.0 Unported License http:// creativecommons. org/ licenses/ by/ 4. 0/, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited
Additional Information : Embargo OK Metadata OK No Further Action
Depositing User : James Marshall
Date Deposited : 24 Aug 2020 14:51
Last Modified : 24 Aug 2020 14:51

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