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Profiling individual human red blood cells using common-path diffraction optical tomography

Kim, Youngchan, Shim, Hyoeun, Kim, Kyoohyun, Park, HyunJoo, Jang, Seongsoo and Park, YongKeun (2014) Profiling individual human red blood cells using common-path diffraction optical tomography Scientific Reports, 4 (1), 6659.

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Abstract

Due to its strong correlation with the pathophysiology of many diseases, information about human redblood cells (RBCs) has a crucial function in hematology. Therefore, measuring and understanding themorphological, chemical, and mechanical properties of individual RBCs is a key to understanding thepathophysiology of a number of diseases in hematology, as well as to opening up new possibilities fordiagnosing diseases in their early stages. In this study, we present the simultaneous and quantitativemeasurement of the morphological, chemical, and mechanical parameters of individual RBCs employingoptical holographic microtomography. In addition, it is demonstrated that the correlation analyses of theseRBC parameters provide unique information for distinguishing and understanding diseases.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
NameEmailORCID
Kim, Youngchanyoungchan.kim@surrey.ac.uk
Shim, Hyoeun
Kim, Kyoohyun
Park, HyunJoo
Jang, Seongsoo
Park, YongKeun
Date : 17 October 2014
DOI : 10.1038/srep06659
Copyright Disclaimer : This work is licensed under a Creative Commons Attribution-Non Commercial-ShareAlike 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/
Projects : Global Ph.D. Fellowship
Depositing User : James Marshall
Date Deposited : 29 Jun 2020 10:30
Last Modified : 29 Jun 2020 10:30
URI: http://epubs.surrey.ac.uk/id/eprint/858083

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