Common-path diffraction optical tomography with a low-coherence illumination for reducing speckle noise

Shin, Seungwoo, Kim, Youngchan, Lee, KyeoReh, Kim, Kyoohyun, Kim, Young-Jin, Park, HyunJoo and Park, YongKeun (2015) Common-path diffraction optical tomography with a low-coherence illumination for reducing speckle noise In: SPiE BIOS, 2015, San Francisco, California, United States.

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Abstract

Common-path diffraction optical tomography (cDOT) is a non-invasive and label-free optical holographic technique for measuring both the three-dimensional refractive index (RI) tomograms and two-dimensional dynamic phase images of a sample. Due to common-path geometry, cDOT provides quantitative phase imaging with high phase sensitivity. However, the image quality of the cDOT suffers from speckle noise; the use of a monochromatic laser inevitably results in the formation of parasitic fringe patterns in measured quantitative phase images. Here, we present a technique to reduce speckle noise in the cDOT using a low-coherence illumination source. Utilizing a Ti-sapphire pulsed laser in the cDOT, we achieved the reduction of speckle noise in both the three-dimensional RI tomograms and two-dimensional dynamic phase images.

Item Type:	Conference or Workshop Item (Conference Paper)
Divisions :	Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :	Name Email ORCID Shin, Seungwoo Kim, Youngchan youngchan.kim@surrey.ac.uk Lee, KyeoReh Kim, Kyoohyun Kim, Young-Jin Park, HyunJoo Park, YongKeun
Date :	11 March 2015
DOI :	10.1117/12.2175845
Copyright Disclaimer :	© (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Depositing User :	James Marshall
Date Deposited :	29 Jun 2020 10:16
Last Modified :	06 Jul 2020 08:47
URI:	http://epubs.surrey.ac.uk/id/eprint/858082

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