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Adaptive Multiphoton Endomicroscope Incorporating a Polarization-Maintaining Multicore Optical Fibre

Kim, Youngchan, Warren, Sean C., Stone, James M., Knight, Jonathan C., Neil, Mark A. A., Paterson, Carl, Dunsby, Chris W. and French, Paul M. W. (2015) Adaptive Multiphoton Endomicroscope Incorporating a Polarization-Maintaining Multicore Optical Fibre IEEE Journal of Selected Topics in Quantum Electronics, 22 (3). pp. 171-178.

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Abstract

We present a laser scanning multiphoton endomicro-scope with no distal optics or mechanical components that incor-porates a polarization-maintaining (PM) multicore optical fibre todeliver, focus, and scan ultrashort pulsed radiation for two-photonexcited fluorescence imaging. We show theoretically that the use ofa PM multicore fibre in our experimental configuration enhancesthe fluorescence excitation intensity achieved in the focal spot com-pared to a non-PM optical fibre with the same geometry and con-firm this by computer simulations based on numerical wavefrontpropagation. In our experimental system, a spatial light modulator(SLM) is utilised to program the phase of the light input to each ofthe cores of the endoscope fibre such that the radiation emergingfrom the distal end of the fibre interferes to provide the focusedscanning excitation beam. We demonstrate that the SLM can en-able dynamic phase correction of path-length variations across themulticore optical fibre whilst the fibre is perturbed with an updaterate of 100 Hz

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
NameEmailORCID
Kim, Youngchanyoungchan.kim@surrey.ac.uk
Warren, Sean C.
Stone, James M.
Knight, Jonathan C.
Neil, Mark A. A.
Paterson, Carl
Dunsby, Chris W.
French, Paul M. W.
Date : 7 October 2015
DOI : 10.1109/JSTQE.2015.2488283
Copyright Disclaimer : This work is licensed under a Creative Commons Attribution 3.0 License. For more information, see http://creativecommons.org/licenses/by/3.0/
Depositing User : James Marshall
Date Deposited : 29 Jun 2020 09:06
Last Modified : 29 Jun 2020 09:06
URI: http://epubs.surrey.ac.uk/id/eprint/858080

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