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Jones matrix-based speckle-decorrelation angiography using polarization-sensitive optical coherence tomography

Gong, Peijun, Li, Qingyun, Karnowski, Karol and Sampson, David (2020) Jones matrix-based speckle-decorrelation angiography using polarization-sensitive optical coherence tomography Journal of Biophotonics.

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Abstract

We show that polarization-sensitive optical coherence tomography angiography (PS-OCTA) based on full Jones matrix assessment of speckle decorrelation offers improved contrast and depth of vessel imaging over conventional OCTA. We determine how best to combine the individual Jones matrix elements and compare the resulting image quality to that of a conventional OCT scanner by co-locating and imaging the same skin locations with closely matched scanning setups. Vessel projection images from finger and forearm skin demonstrate the benefits of Jones matrix-based PS-OCTA. Our study provides a promising starting point and a useful reference for future pre-clinical and clinical applications of Jones matrix-based PS-OCTA.

Item Type: Article
Divisions : Surrey research (other units)
Authors :
NameEmailORCID
Gong, Peijun
Li, Qingyun
Karnowski, Karol
Sampson, Davidd.sampson@surrey.ac.uk
Date : 16 May 2020
Funders : Australian Government International Research Training Program
DOI : 10.1002/jbio.202000007
Copyright Disclaimer : This article is protected by copyright. All rights reserved.
Uncontrolled Keywords : angiography; Jones matrix; polarization-sensitive optical coherence tomography; skin microvasculature; speckle decorrelation
Additional Information : Article is currently undergoing final revisions and has a version online on the publisher's website, but that is not the final version.
Depositing User : James Marshall
Date Deposited : 16 Jun 2020 09:03
Last Modified : 16 Jun 2020 09:03
URI: http://epubs.surrey.ac.uk/id/eprint/857985

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