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The COVID-19 MS Coalition—accelerating diagnostics, prognostics, and treatment

Struwe, Weston, Emmott, Edward, Bailey, Melanie, Sharon, Michal, Sinz, Andrea, Corrales, Fernando J, Thalassinos, Kostas, Braybrook, Julian, Mills, Clare and Barran, Perdita (2020) The COVID-19 MS Coalition—accelerating diagnostics, prognostics, and treatment The Lancet, 395 (10239). pp. 1761-1762.

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Rapid and comprehensive genetic sequencing has shed light on the origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and allowed timely implementation of PCR tests to determine the presence of viral RNA. PCR tests for SARS-CoV-2 are some way from being reliably qualitative and will never indicate how the disease might progress in an individual. As COVID-19 becomes endemic, there is a concomitant need for accurate serological assays to detect antibodies to SARS-CoV-2 antigens and ultimately tests for prognostic markers to target treatment options.1,2 With this considerable genetic insight, and the emerging structural information, comes associated questions regarding the molecular descriptors that contribute to disease progression, especially when we consider spread across different populations. The power of mass spectrometry to generate rapid, precise, and reproducible diagnostic information that complements genomic information and accelerates our understanding of the disease, is now becoming a reality.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Chemistry
Authors :
Struwe, Weston
Emmott, Edward
Sharon, Michal
Sinz, Andrea
Corrales, Fernando J
Thalassinos, Kostas
Braybrook, Julian
Mills, Clare
Barran, Perdita
Date : 27 May 2020
DOI : 10.1016/S0140-6736(20)31211-3
Copyright Disclaimer : © 2020 Elsevier Ltd. All rights reserved.
Depositing User : Clive Harris
Date Deposited : 12 Jun 2020 14:17
Last Modified : 12 Jun 2020 14:17

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