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Cost effectiveness of endosonography versus surgical staging in potentially resectable lung cancer: a health economics analysis of the ASTER trial from a European perspective

Rintoul, Robert C, Glover, Matthew J, Jackson, Christopher, Hughes, Victoria, Tournoy, Kurt G, Dooms, Christophe, Annema, Jouke T and Sharples, Linda D (2014) Cost effectiveness of endosonography versus surgical staging in potentially resectable lung cancer: a health economics analysis of the ASTER trial from a European perspective Thorax, 69 (7). pp. 679-681.

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Abstract

In the ASTER study, mediastinal staging was more accurate for patients randomised to combined endobronchial and endoscopic ultrasound, followed by surgical staging if endoscopy was negative, versus surgical staging alone. Here, we report survival, quality of life and cost effectiveness up to 6 months, for the UK, The Netherlands and Belgium, separately. Survival in the two arms of the study was similar. In all three countries, the endosonography strategy had slightly higher quality-adjusted life years over 6 months, and was cheaper. Therefore, based on clinical accuracy and cost effectiveness, we conclude that mediastinal staging should commence with endosonography.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
NameEmailORCID
Rintoul, Robert C
Glover, Matthew Jmatthew.glover@surrey.ac.uk
Jackson, Christopher
Hughes, Victoria
Tournoy, Kurt G
Dooms, Christophe
Annema, Jouke T
Sharples, Linda D
Date : 10 June 2014
Funders : National Health Service, Medical Research Council (MRC), National Institute for Health Research (NIHR)
DOI : 10.1136/thoraxjnl-2013-204374
Grant Title : R&D Health Technology Assessment programme
Depositing User : Clive Harris
Date Deposited : 29 Apr 2020 15:47
Last Modified : 29 Apr 2020 15:47
URI: http://epubs.surrey.ac.uk/id/eprint/855409

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