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Reconstructed human epidermis: A model to study the barrier function

Barbotteau, Y., Gontier, E., Barbaret, P., Cappadoro, M., De Wever, B., Cappadoro, M., Habchi, C., Incerti, S., Mavon, A., Moretto, P. , Pouthier, T., Smith, Richard and Ynsa, M.D (2005) Reconstructed human epidermis: A model to study the barrier function Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 231 (1-4).

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Abstract

The use of in vitro reconstructed human epidermis (RHE) by the cosmetic and pharmaceutical industries is increasing because of its similar physiological mechanisms to native human skin. With the advent of ethic laws on animal experimentation, RHE provides an helpful alternative for the test of formulations. The aim of this study is to check that the RHE mineral status is comparable to that of human native skin by investigating the elemental distributions in the epidermis strata. In addition, possible deleterious effects of the transport on the epidermis ionic content were studied by nuclear microscopy.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Electronic Engineering
Authors :
NameEmailORCID
Barbotteau, Y.
Gontier, E.
Barbaret, P.
Cappadoro, M.
De Wever, B.
Cappadoro, M.
Habchi, C.
Incerti, S.
Mavon, A.
Moretto, P.
Pouthier, T.
Smith, Richardr.w.smith@surrey.ac.uk
Ynsa, M.D
Date : 9 April 2005
DOI : 10.1016/j.nimb.2005.01.07
Copyright Disclaimer : © 2005 Elsevier B.V. All rights reserved.
Uncontrolled Keywords : Reconstructed human epidermis; Skin; Nuclear microscopy; Micro-PIXE
Depositing User : James Marshall
Date Deposited : 23 Mar 2020 12:10
Last Modified : 23 Mar 2020 12:10
URI: http://epubs.surrey.ac.uk/id/eprint/854070

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