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Exploring a route to a selective and sensitive portable system for explosive detection– swab spray ionisation coupled to of high-field assisted waveform ion mobility spectrometry (FAIMS)

Costa, Catia, van Es, E.M., Sears, P., Bunch, J., Palitsin, Vladimir, Cooper, H. and Bailey, M.J. (2019) Exploring a route to a selective and sensitive portable system for explosive detection– swab spray ionisation coupled to of high-field assisted waveform ion mobility spectrometry (FAIMS) Forensic Science International: Synergy, 1. pp. 214-220.

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Abstract

Paper spray mass spectrometry is a rapid and sensitive tool for explosives detection but has so far only been demonstrated using high resolution mass spectrometry, which bears too high a cost for many practical applications. Here we explore the potential for paper spray to be implemented in field applications with portable mass spectrometry. This involved (a) replacing the paper substrate with a swabbing material (which we call “swab spray”) for compatibility with standard collection materials; (b) collection of explosives from surfaces; (c) an exploration of interferences within a ± 0.5 m/z window; and (d) demonstration of the use of high-field assisted waveform ion mobility spectrometer (FAIMS) for enhanced selectivity. We show that paper and Nomex® are viable collection materials, with Nomex providing cleaner spectra and therefore greater potential for integration with portable mass spectrometers. We show that sensitive detection using swab spray will require a mass spectrometer with a mass resolving power of 4000 or more. We show that by coupling the swab spray ionisation source with FAIMS, it is possible to reduce background interferences, thereby facilitating the use of a low resolving power (e.g. quadrupole) mass spectrometer.

Item Type: Article
Divisions : Faculty of Engineering and Physical Sciences > Chemistry
Authors :
NameEmailORCID
Costa, Catiac.d.costa@surrey.ac.uk
van Es, E.M.
Sears, P.p.sears@surrey.ac.uk
Bunch, J.
Palitsin, VladimirV.Palitsin@surrey.ac.uk
Cooper, H.
Bailey, M.J.M.Bailey@surrey.ac.uk
Date : 2019
Funders : UK Government's CONTEST strategy, Engineering and Physical Sciences Research Council (EPSRC)
DOI : 10.1016/j.fsisyn.2019.07.009
Grant Title : Innovative Research Call in Explosives and Weapons Detection 2016
Copyright Disclaimer : © 2019 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Forensic Science International: Synergy 1 (2019) 214e220
Depositing User : Clive Harris
Date Deposited : 27 Nov 2019 17:48
Last Modified : 27 Nov 2019 17:48
URI: http://epubs.surrey.ac.uk/id/eprint/853210

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