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Renal Effects of SGLT-2 Inhibitors and Other Anti-diabetic Drugs: Clinical Relevance and Potential Risks

Lioudaki, E, Whyte, M, Androulakis, ES, Stylianou, KG, Daphnis, EK and Ganotakis, ES (2017) Renal Effects of SGLT-2 Inhibitors and Other Anti-diabetic Drugs: Clinical Relevance and Potential Risks Clinical Pharmacology & Therapeutics, 102 (3). pp. 470-480.

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Abstract

Type 2 diabetes mellitus (T2DM) is a metabolic disease affecting an increasing percentage of general population worldwide. Patients with T2DM are frequently characterized by impaired renal function, primarily as a result of diabetic kidney injury, but also by other contributing factors, such as hypertension, atherosclerosis, and medications. Sodium‐glucose cotransporter (SGLT)‐2 inhibitors have emerged as a new, promising class of antidiabetic agents with actions that seem to extend beyond their hypoglycemic effect.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
NameEmailORCID
Lioudaki, E
Whyte, Mm.b.whyte@surrey.ac.uk
Androulakis, ES
Stylianou, KG
Daphnis, EK
Ganotakis, ES
Date : 21 July 2017
DOI : 10.1002/cpt.731
Copyright Disclaimer : © 2017 American Society for Clinical Pharmacology and Therapeutics
Depositing User : Clive Harris
Date Deposited : 25 Sep 2019 09:53
Last Modified : 25 Sep 2019 09:53
URI: http://epubs.surrey.ac.uk/id/eprint/852785

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