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Peri-operative renal dysfunction: Prevention and management

Golden, D., Corbett, J. and Forni, Lui G. (2016) Peri-operative renal dysfunction: Prevention and management Anaesthesia, 71 (S1). pp. 51-57.

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Postoperative increases in serum creatinine concentration, by amounts historically viewed as trivial, are associated with increased morbidity and mortality. Acute kidney injury is common, affecting one in five patients admitted with acute medical disease and up to four in five patients admitted to intensive care, of whom one in two have had operations. This review is focused principally on the identification of patients at risk of acute kidney injury and the prevention of injury. In the main, there are no interventions that directly treat the damaged kidney. The management of acute kidney injury is based on correction of dehy dration, hypotension, and urinary tract obstruction, stopping nephrotoxic drugs, giving antibiotics for bacterial infection, and commencing renal replacement therapy if necessary.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
Golden, D.
Corbett, J.
Forni, Lui
Date : 1 December 2016
DOI : 10.1111/anae.13313
Copyright Disclaimer : © 2015 The Association of Anaesthetists of Great Britain and Ireland
Depositing User : Diane Maxfield
Date Deposited : 23 Sep 2019 13:57
Last Modified : 23 Sep 2019 13:57

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