Porcine Dendritic Cells and Viruses: An Update

Franzoni, Giulia, Graham, Simon P., Dei Giudici, Silvia and Oggiano, Annalisa (2019) Porcine Dendritic Cells and Viruses: An Update Viruses, 11 (5).

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Abstract

Several viral infections of swine are responsible for major economic losses and represent a threat to the swine industry worldwide. New tools are needed to prevent and control endemic, emerging, and re-emerging viral diseases. Dendritic cells (DC) play a central role in linking the innate and adaptive arms of the immune system, so knowledge regarding their interaction with pathogens is necessary to understand the mechanisms underlying diseases pathogenesis and protection. In the first part of this review, we provide an update on the heterogeneous cell subsets that comprise the porcine DC family. In the second part of this review, we provide an overview of how three viruses, affecting pork production at a global level, African swine fever virus (ASFV), classical swine fever virus (CSFV), and porcine circovirus 2 (PCV2), modulate DC function.

Item Type:	Article
Divisions :	Faculty of Health and Medical Sciences > School of Veterinary Medicine
Authors :	Name Email ORCID Franzoni, Giulia Graham, Simon P. s.graham@surrey.ac.uk Dei Giudici, Silvia Oggiano, Annalisa
Date :	16 May 2019
DOI :	10.3390/v11050445
Copyright Disclaimer :	© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Uncontrolled Keywords :	Pig; Dendritic cells; ASFV; CSFV; PCV2
Depositing User :	Clive Harris
Date Deposited :	23 May 2019 08:46
Last Modified :	23 May 2019 08:46
URI:	http://epubs.surrey.ac.uk/id/eprint/851880

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