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Cooperative development of logical modelling standards and tools with CoLoMoTo

Naldi, A., Monteiro, P.T., Müssel, C., Kestler, H.A., Thieffry, D., Xenarios, I., Saez-Rodriguez, J., Helikar, T., Chaouiya, C., Albert, R. , Barberis, M., Calzone, L., Chasapi, A., Cokelaer, T., Crespo, I., Dorier, J., Dräger, A., Hernandez, C., Hucka, M., De Jong, H., Keating, S.M., Klamt, S., Klarner, H., Laubenbacher, R., Le Novère, N., Niknejad, A., Rodriguez, N., Siebert, H., Stoll, G. and Zañudo, J.G.T. (2015) Cooperative development of logical modelling standards and tools with CoLoMoTo Bioinformatics, 31 (7). pp. 1154-1159.

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The identification of large regulatory and signalling networks involved in the control of crucial cellular processes calls for proper modelling approaches. Indeed, models can help elucidate properties of these networks, understand their behaviour and provide (testable) predictions by performing in silico experiments. In this context, qualitative, logical frameworks have emerged as relevant approaches, as demonstrated by a growing number of published models, along with new methodologies and software tools. This productive activity now requires a concerted effort to ensure model reusability and interoperability between tools. Following an outline of the logical modelling framework, we present the most important achievements of the Consortium for Logical Models and Tools, along with future objectives. Our aim is to advertise this open community, which welcomes contributions from all researchers interested in logical modelling or in related mathematical and computational developments. © The Author 2014.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
Naldi, A.
Monteiro, P.T.
Müssel, C.
Kestler, H.A.
Thieffry, D.
Xenarios, I.
Saez-Rodriguez, J.
Helikar, T.
Chaouiya, C.
Albert, R.
Calzone, L.
Chasapi, A.
Cokelaer, T.
Crespo, I.
Dorier, J.
Dräger, A.
Hernandez, C.
Hucka, M.
De Jong, H.
Keating, S.M.
Klamt, S.
Klarner, H.
Laubenbacher, R.
Le Novère, N.
Niknejad, A.
Rodriguez, N.
Siebert, H.
Stoll, G.
Zañudo, J.G.T.
Date : 1 April 2015
DOI : 10.1093/bioinformatics/btv013
Copyright Disclaimer : © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail:
Additional Information : No further action
Depositing User : Clive Harris
Date Deposited : 12 Apr 2019 11:53
Last Modified : 03 Oct 2019 10:59

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